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6. Neurology (Medical Knowledge) > [Myaesthenia Gravis] > Flashcards

[Myaesthenia Gravis] Flashcards

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USMLE® Step 1 flashcards
1
Q
A

Myaesthenic snarl
(preserved vertical but decreased horizontal excursion of lips)

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2
Q
A

voice fades on counting to 50

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3
Q
A

Tendon reflexes normal

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4
Q
A

Females
Thymic hyperplasia

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5
Q
A

Males
thymic atrophy/tumours

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6
Q
A

nicotinic acetylcholine receptors

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7
Q
A

ocular muscle fatigue
difficulty swallowing/speaking

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8
Q
A

Shows orbicularis fatigue

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9
Q
A

Anti-AchR

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10
Q
A

70

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11
Q
A

MuSK (muscle specific tyrosine kinase)

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12
Q
A

Decremental muscle response

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13
Q
A

> 2mm

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14
Q
A

CT of thymus

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15
Q
A

Pyridostigmine (anticholinesterase)

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16
Q
A

Prednisolone
+ azathioprine/d
OR
Methotrexate /week

17
Q
A

alternate days

18
Q
A

Osteoporotic prophylaxis

19
Q
A

methotrexate

20
Q
A

azothioprine

21
Q
A

Thymectomy

22
Q
A

respiratory muscle fatigue during relapse

23
Q
A

Forced vital capacity

24
Q
A

FBC
LFT

25
Q
A

ocular
(bulbar, face, neck, limb)
Truck

26
Q
A

salivation
lacrimation
miosis

27
Q
A

IV Immunoglobulin

28
Q
A

life threatening weakness of respiratory muscles in relapse

29
Q
A

<20mL/Kg

30
Q
A

plasmapheresis
or
IV Ig

31
Q

[lambert-eaton}: what is the difference in presentation between MG and LE myasthenic syndrome?

A

gait difficulty before eye signs

32
Q

[lambert-eaton}: what is the pathophysiological cause of LES?

A

Antibodys against pre-synaptic membrane Calcium voltage channels

33
Q

[lambert-eaton}:LES can be autoimmune or caused by …

A

small cell lung cancer (paraneoplastic)

6. Neurology (Medical Knowledge) (24 decks)

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