Parkinson/Huntington

Question 1

Sudden Jerky, purposeless movments? What disease?

Answer 1

Chorea

Huntington

Question 2

Huntington has a deficiency in?

Answer 2

Caudate loses Ach and GABA

Ach and GABA

Question 3

What are Slow, writhing movements that are snake like? What disease

Answer 3

Athetosis

Huntington

Question 4

Sudden, wild flailing of 1 arm? What disease?

Answer 4

Hemiballismus
Half-of-body ballistic
Contralateral subthalamic nucleus (e.g., lacunar stroke)

Question 5

zigzag motion when pointing/extending toward a target?

Answer 5

Intention Tremor

Cerebellar dysfunction

Question 6

Uncontrolled movement of distal appendages?

Answer 6

Resting Tremor

Parkinson

Question 7

What are two bodies of Parkinson?

Answer 7

Lewy Bodies

å synucleins

Question 8

In Parkinson you lose?

Answer 8

Depigmentation of substantia nigra pars compacta.

Question 9

Parkinson TRAPS?

Answer 9

Tremor (pill-rolling tremor at rest) 
Rigidity (cogwheel)
Akinesia (or bradykinesia) 
Postural instability
Shuffling gait

Question 10

Huntington’s Disease in chromosome??

Answer 10

Autosomal dominant CAG repeat disorder on chromosome 4.

Question 11

Symptoms of Huntington?

Answer 11

aggression, depression, dementia

Question 12

Neuronal Death is due to?

Answer 12

NMDA binds to glutamate and cause death