Meningitis Flashcards
Name the top 3 MCC of meningitis in the newborn.
Group B streptococci
E. Coli
Listeria
MCC of meningitis in 6 months to 6 years?
N. Meningitidis
How does N. Meningitidis enter into the brain?
Enters via nasopharynx=>blood=>Brain
MCC of meningitis in Teens?
N. Meningitidis
For adults, MCC of Meningitis?
S. Pneumoniae
MCC of viral meningitis?
Enteroviruses (esp. coxsackievirus)
MCC of HIV meningitis?
Cryptococcus
MCC of unimmunized children?
H. Influ
What has reduced greatly with introduction of conjugate H. Influ vaccine?
H. Influ Meningitis
Stick Needle in between where?
L3-L5
For bacterial, CSF would show?
Low Sugar
High Protein
Increased PMNs
For Fungal, CSF would show?
Low Sugar
High Protein
Increased Lymphocytes
For Viral, CSF would show?
All are normal except increased Lymphocytes
Complications of meninigitis is most likely seen in?
Bacterial meningitis
What are these complications?
Herniation, Hydrocephalus, hearing loss
Treatment of Meningitis?
Ceftriaxone, vancomycin and add ampillcin if listeria is present
L3-L5 is at the level of
Cauda equina
Neisseria meningitidis can lead to wide spread?
DIC, Petechial rash, Adrenal Hemorrhage
Meningitis vaccine cover all capsules except?
B
Does Meningitidis ferment just glucose?
No, Maltose and Glucose
Two main virulence factor of Meningitidis?
IgA protease
Capsular
NessierCIA
HIV patient with headache and fever?
Cryptococcus
Cryptococcus is most commonly found in?
pigeon poop
Virulence factor of Cryptococcus?
Thick Polysaccharide capsule (repeating antigen)
Budding yeast with thick capsule?
Cryptococcus
Sarcophagus
Where does Cryptococcus first affect?
Lungs
Coughing
What do you see in an x-ray with Cryptococcus?
SOAP Bubble lesions
SOAP BUBBLE on mummy
Two tests to get Cryptococcus?
Latex Agglutinins (Latex gloves) India Ink (Milwaukee Bucks)
Tx of Cryptococcus?
Amphotericin B+Flucytosine
Collection of students/Army recruits?
Nessieria Meningiditis
Kidney Bean-Shaped Gram neg. Cocci?
Nessieria Meningiditis
What in Nessieria Meningitidis causes death?
LOS outer membrane lipooligosaccharide
MCC of bacterial meningitis?
S. pneumoniae
Narrow Zone of ß-Hemolysis?
Listeria Monocytogenes
Listeria Monocytogenes description?
Tumbling motility
Does Listeria grow well in Cold Temperatures?
Yes
In what way does Listeria get into the body?
Cheese, unpasteurized milk
Tx of Meningitis?
Ceftriaxone (think Meningitidis) and ampicillin
Why do you add ampicillin to the Tx?
For Listeria