parkinson and huntingtons Flashcards
parkinson
gradual onset/ progressive worsen/ older
2 types
postural instability gait difficulty
tremor domain
causes of parkinson
oxidative hypothesis
genetic PARK gene
prodromal phase
sleep disorder
anxiety
90 percent can’t smell
parkinson symptoms
bradykenesia- slow move
hypokinesia- low amp movement
rigidty
rest tremor
what occurs during parkinson
degeneration of substantia nigra- release of dopamine
intraneuronal changes- lewie body- accumulation of protein
vagus nerve/ olfactory nerve
autonomic disturbances
slept motor disturbance
emotional cognitive disturbance
impairment of parkinson
resting hand tremor
akinesia
impaired recall memory
apathy
anxiety
depression
dystonia
difficulty comprehension
management pharmacological parkinson
dopamine replacement- Levodopa -= reverse some movement disorders
dopamine agonist- minimise dopamine effects
side effects
= dyskineia
hallucination
impulse control disorders
deep brain stimulation
electrode implanted in brain to target the subthalamic nucelus
globus pallidus internus
ventral intermediate thalamus
huntingtons disease
genetic disorder = 50 percent getting it if your parent has it
huntingtons disease structural changes
CAG- expansion on 4th chromosme huntingtons proteins
Death of neurons in caudate/ putamen
go pathway- overactive
increase output of motor cortex
unwanted movements- twtiches
voluntary movements- poor control
extraneous movements
impairments of huntingtons
movement disorders- bradykinesia/ hypokinesia, dysathria, swallowing
cognitive- attention deficet/ difficult with dual task
emotional- apathy, initable, impulsive
communication- decrease iniative
metabolic- weight loss
neural biasis rehab motor early stage
Task-specific training for rate of
speech and breathing, gait, mobility
and upper limb training
functional restortative
neural biasis rehab motor mid stage
Training gait and postural
stability to reduce frequency of
falls. Environment modification
to increase safety.
compensatory
neural biasis rehab motor late stage
Management of mobility, seating,
self-care, prevention of
contracture, maintenance of safe
swallow
pallitive
cognition neural baisis early stage
Strategies to assist memory,
planning, problem solving, attention
cognition neural biasis mid stage
Compensatory strategies in
place to assist with memory,
task initiation
cognition neural biasis late stage
Assistance with cognitive tasks
emotional neural biasis early stage
Management of depressions,
apathy and fatigu
emotional neural biasis mid stage
Management of depression and
anxiety, irritability and
impulsiveness
emotional neural baisis late stage
Cognitive impairments may mask
emotional impairments
