basal ganglia Flashcards

1
Q

basal ganglia

A

collection of deep nuclei- grey matter because deep

  • caudate
    -putamen

-globus palidus- internus and externus

-subthalamic nucleus

-substania nigra

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2
Q

basal ganglia function

A

goal directed behaviour loop - non motor
social behaviour loop- non motor
emotional loop- non motor
motor loop

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3
Q

basal ganglia movement

A

regulates desired movements and inhibits undesired movements

e.g voluntary movement, postural muscle, rythmic

regulates muscle tone and force

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4
Q

3 pathways for motor loop

A

hyper direct
direct
indirect

cortico-basal ganglia-thalmic loop

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5
Q

accelerator pathway

A

direct allows movement

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6
Q

brake pathway

A

indirect- inhibits movements

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7
Q

direct pathway

A

cerebellum sends exitory info from motor cortex to
caudate and putamen
substantia nigra (pars compacta)
sends dopamine as well

striatum sends inhibitory neurotransmitters- GABBA

Globus pallidus internus-
this doesn’t then send output and inhibit the thalmus

thalamus excites motor cortex

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8
Q

indirect pathway

A

globus pallidus externus gets GABBA from the striatum

will not inhibit the subthalamus

subthalamus releases glutamine which is excitory

then the globus pallidus internus is excited and will inhibit the thalamus

and so inhibits the motor cortex

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9
Q

motor control relies on

A

dopamine releasing neurons found in substantia nigra

  • direct- dopamine- D1- receptors= inhibit
    indirect- dopamine- d2 receptors- excite
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10
Q

dopamine

A

neurotransmitter found in substania nigra

will enhance the direct pathway

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