Parathyroid disease Flashcards
What are the parathyroid glands derived from embryologically?
Superior pair - 4th branchial pouch
Inferior pair - 3rd branchial pouch
Which pair of parathyroid glands position is variable and why?
Inferior because they migrate further
Name symptoms of hypoparathyroidism
Hypocalcemia!
Chvostek sign Trousseau sign Tetanic muscle spasm Coma Convulsions Death
What is the most common cause of hypoparathyroidism?
Thyroidectomy
Name causes of hyperparathyroidism
Parathyroid adenoma (most common) Parathyroid hyperplasia - chronic renal failure - short bowel syndrome - MEN syndrome
Name the symptoms of hypercalcemia
Stones, bones, moans and groans
What is calcium normally bound to?
Albumin
Name blood findings in primary hyperparathyroidism
Increased serum calcium
Increased PTH
Decreased phosphate
Increased urinary calcium excretion
How can parathyroid glands be localized for surgery?
MIBI radioisotope