Parathyroid disease Flashcards

1
Q

What are the parathyroid glands derived from embryologically?

A

Superior pair - 4th branchial pouch

Inferior pair - 3rd branchial pouch

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2
Q

Which pair of parathyroid glands position is variable and why?

A

Inferior because they migrate further

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3
Q

Name symptoms of hypoparathyroidism

A

Hypocalcemia!

Chvostek sign
Trousseau sign 
Tetanic muscle spasm
Coma
Convulsions
Death
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4
Q

What is the most common cause of hypoparathyroidism?

A

Thyroidectomy

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5
Q

Name causes of hyperparathyroidism

A
Parathyroid adenoma (most common) 
Parathyroid hyperplasia 
- chronic renal failure
- short bowel syndrome
- MEN syndrome
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6
Q

Name the symptoms of hypercalcemia

A

Stones, bones, moans and groans

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7
Q

What is calcium normally bound to?

A

Albumin

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8
Q

Name blood findings in primary hyperparathyroidism

A

Increased serum calcium
Increased PTH
Decreased phosphate
Increased urinary calcium excretion

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9
Q

How can parathyroid glands be localized for surgery?

A

MIBI radioisotope

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