parasitology lecture 5 Flashcards
kinetoplasts, 3 clinically relevant
leischmania
trypanasome brucei (sleeping sickness)
trapanasome cruzi (chagas)
leishmania transmitted by _
most are _ (location)
requires _ bites
replicates inside _
sandfly
cutaneous
two bites
replicates inside macrophage
cutaneous _
leishmaniasis
visceral _
leishmaniasis
onset at 2-12 months
fever and wasting
splenomegaly and or hepatomegaly
chemotherapeutic cure leads to immunity
African trypanosomiasis
T. brucei brucei affects _
T. brucei rhodesiense _
T. Brucei gambiense _
cattle
humans acute
humans chronic
trypanosomiasis vector
tsetse fly
trypanosomiasis is a good example of a _ infectious disease
reemerging
wars caused public health to decline
pattern of parasitemia in T brucei
waves. impossible to make a vaccine. changes often.
what is winterbottoms sign?
enlargement of the posterior cervical nodes
T brucei
Trypanasoma cruzi (chagas disease) south america
reservoir
location in body
transmission vector
rats, cats, dogs, opossums, etc
blood, lymphatics, tissues (intracellular)
transmission- vector borne- reduvid bugs. transfusion, transplant, iv drug use
parasite STD
trichomonas vaginalis
trichomoniasis symptoms
immunity?
frothy discharge, smell, otherwise asymptompatic
no immunity
