Parasitology

Question 1

Common intestinal parasites in saudi arabia

Answer 1

Entamoeba histolytica
Giardia lambila
Ascaris
Schistosoma manoni

Question 2

Common parasitic skin infection in saudi arabia

Answer 2

Leishmania major
leishmania tropica

Question 3

Categorization of parasites according to affecting tissue

Answer 3

Blood and tissue protoza
intestinal and vaginal protozoa
interstinal helminths
Blood and tissute helminths

Question 4

Parasite of rbc (protozoa)

Answer 4

Plasmodium
Babesia

Question 5

Plasmodium (PROTOZOA) which can infect rbc . what is the mode of entery and symptoms

Answer 5

MOE: mosquito vector (f) Anopheles . Symptoms develop after 8-30 days

S:
-fever , chill (Malarrial paroxysm)
-Lysis of Rbc and cause anemia
-Surge IL-1 and GDPI.

Question 6

what are the diffrent types of plasmodium

Answer 6

p.falciparum
p.knowlesi
p.vivax
p.ovale
p.malariae

Question 7

Sypmptos of , P.Falc P.know P.vivax

Answer 7

all fever - chill

P.falc : Nausea and vomationg , diarrhea progressing to tertian (every 2 days a fever ) with filminating diseases (malignant tertian)

P.know:Headache , rigors (sudden feeling of cold ) ,abdominal pain , cough (severe symptoms in 7 % of cases ; respiratory and hepatorenal failure)

P.vivax : (benign tertian malaria ) - life threatiening syndromes similar to p.falc may be seen . A LIVER STAGE MAY CAUSE RELAPSES AND RECRUDESCENSCES

Question 8

SYMPTOMS OF P.ovale - P.malariae

Answer 8

P.ovale ; cause (benign tertian malaria ) like p vivax with both relapeses and recuarance

P.malariae : Has a long incubation period , fever in intreval 3 to 4 days (quartan or malarial malaria )

Question 9

Lab diagnosis of Parasite of rbc, what stain , what we see in the microscopic picture of P.falc , P.vivax

Answer 9

Giemsa - stain (thin for species - thick for if it is there )

P.falc :Multipe ring form - applique (see page 11)
P.vivax :Ring withdouble chromatin dots , contain schuffiner dots

Question 10

Babesia species (PROTOZOA) which can infect rbc . what is the mode of entery and symptoms

Answer 10

MOA:Tick vector

Symptoms (Babesiosis) : -Fever - chills - Muscle aches !!! - dark urine . diffcult to diagnose

Question 11

Babesia lab ( what stain) and and what is the dignosing tests AND THE microscopic feature

Answer 11

Giemsa stain , resmable Plasmodium

DT:Antibodes based test ELISA

PCR

MF:Multibe ring like p.falc

Question 12

What are the parasite of tissue

Answer 12

Toxoplasma dondii
Leismanina

Question 13

Entery of Toxoplasma gondii (tissue )

Answer 13

Entery :
uncoocked meet containg cysts
ingesting oocyte found in feces of cats \

Imp to know : cats are required for lifecycle of T.gondi (no cats no toxo )

Question 14

symptoms of toxoplasma 6

Answer 14

Aids patient (mononuleosis - like syndrome , congential infection , infecton of heart and brand (encaplatis)
Body aches
headach
swollen lymh nodes!!!!!!!!
fatigue

Question 15

Lab of Toxoplasma. stain used ? what is the best test used for -Immunocomparmised - not immunecompramised . what the microsopic feature

Answer 15

IgM for normal people - MRI for IC

Microscopic: lostf of cyst which can become actiive in IC ( Like those with immuncesupression drugs who got a trasnplant surgery )

Question 16

Leishmania (tissue protoza) Entery and reserviors

Answer 16

Phelbotomine sand flies vector

reserviors are rodents + dogs

Question 17

Leishmania (tissue protoza) symtomps

Answer 17

Cutanous leishamnaiasis (L.tropica)
Visceral leishmaniasis (L.donovani)
Fever , weight loss , skin lessions

Lession in :
Liver (hepatomegaly )
spleen (spleeomegaly )
bone marrow (anemia , leukopenia and thrombocytopenia )

Question 18

Leishmania (tissue protoza) lab dignosis

Answer 18

Biopsy for (visceral leishmaniasis )
PCR
detection of parasitic Ag in urine

Question 19

what are the Intestinal protoza

Answer 19

Entamoeba histolytica - giardia lambila

Question 20

Entamoeba histolytica (Intestinal protoza ) sympyoms and transmation

Answer 20

Fecal - oral route

Dysenteric stoll (watery&bloody with mucus ) and colonic ulcer

lower abdoman discormfort , flatuelence & tenesmus
Weight loss , fatigue , Amebic abscess of the liver

Question 21

Lab diagnosis for Entamoeba histolytica (Intestinal protoza )

Answer 21

Trophozoite in stool
stool imunnoyassy (E,histolyic Ag)
Serologic testing esp for the abscess

Question 22

symptoms of giardia lamblia (Intestinal protoza ) and trasnmation

Answer 22

Fecoal-oral
Persistent diarrhea !!!!!
Malabsorption —-> greast and foul-smelling non bloody diarrhea!!!!!!!!!!!
weight loss + feficiency of fat vitamins

Question 23

Lab diagnoisis of giardia lamblia (Intestinal protoza )

Answer 23

present in stool
dedtion of cyst
ag detection assy in stool

Question 24

name one Intestinal nematodes and entery

Answer 24

ascaris lumbricoides - page 23

Question 25

Symptoms of Ascaris lumbricoides

Answer 25

The damage is primarly due to larval migration Malnutrition in kids ascaris penumonia ( Eosinphilia) Worm cause obstruction + perfooration and occlusion of appendix (cause appendicitis)

Question 26

Lab diagnonis of Ascaris lumbricoides

Answer 26

Eosinphilia occult blood in stool larva in sputum eggs in stool

Question 27

Name one intersinal trematodes`

Answer 27

Schistosoma

Question 28

How schistosoma enter the body

Answer 28

Snail releases cercariae into fresh water the penetrates intact skin

Question 29

Types of schistosoma and what do they infect

Answer 29

S.mansoni and S.japonicum enter circulation and develop in the mesenteric venuleus and later the reach intestine causeing (intestincal schistosomiasi) S.haematobium in bladder vein later reaching the bladder causing ( vesicular schistosomiasi)

Question 30

Schistosoma symptoms

Answer 30

Skin rash - abdominal pain + diarhhea + hepatomegaly and eosinophilia and leukocytosis (katayama syndrome ) 'sensitivty to egg - acute phase' S.man and S.jap cause hepatospenic and neurological damage S.hae cause hematouria dysuria bladder scarring and uropathy

Question 31

lab diagnosis of schistosoma

Answer 31

urine and feces eggs eosinophilia