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Micro > Mycology > Flashcards

Mycology Flashcards

1
Q

Fungal cell wall is made up of?

A

Glucan :act as endotoxin that may stimulate the immune system
Fungal pigments : protect aginst UV

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2
Q

What make fungal cell wall unique from cellullose based palnts

A

1-Glycoproteinens
2-polysaccharides
3-cell membrane

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3
Q

Polysaccharides(glucan B1.3 B1,6) + chitin which is found in cell wall do what

A

The glucan act like endotoxin

chitin(beta-1,4-linked chan of acetylgucosamine ) cotribute to cell wall integrity to withstand osmotic pressures

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4
Q

function of glycoprotiens

A

Transport and cell to cell atachment

important target of innate immune recognition

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5
Q

What is the primary sterol of cell mebrane

A

ergosterol

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6
Q

what makes the cell wall speical for lap result

A

chitin + ergosterol

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7
Q

Difference in cell wall of yeast vs moulds

A

Filamentous fungus molds
Lacks mannan

lacks b-1,6-glucan and replaced with oligosacrride

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8
Q

Function of fungal cell wall

A

Morphogenesis and sensing enviromental stimuli
wall integrity
adhesion to host
Pamps : chitin and b glucan act as pamps or mamps which help the host PRRs to detect the invading fungus

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9
Q

names of divsion

A

Bainary fissin mostly bacteria

budding mostly in yeast : SPOC stops it

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10
Q

what is a spores

A

Asexual and sexual way of sexing

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11
Q

Enodgenous vs exogenous spores

A

endogenous : have a close membrance call sporongium
exogenous :have a free spore called conidispores

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12
Q

What is the mean diffrence between bacteria and fungi

A

Fungi have thermal dimorphism

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13
Q

classification of fungal diseases

A

Superficial mycosis : cutaneous and subcutaneous
Systemic or deep mycosis
opportunistic infection

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14
Q

Superficial mycosis is caused by a group of fungi called ?

name what they require to grow

and way of transmation

A

Dermatophytes

keration

fomites

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15
Q

Name 3 superficial skin infection caused by dermatophytes

A

Microsporum
Trichophyton
epidermophton

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16
Q

where dose subcuatneous mycosis present in nature

A

Presnt of plant and soil so farmer are affected commonly

17
Q

give me one example of subcuatnous mycosis and what fungi

A

Sporotrichiosis cause my the fungi sporothrix schenkii

18
Q

progression of subcutanous mycosis and how it start and what is the immune respone

A

start is paionless nodule then ulcerate dishchargin serous or purelnt fluid. spred thro lymptics forming nodular lesion

neutrophils

19
Q

look at page 30 for pitcure of spoorothrix schenkii

A
20
Q

Systemic mycosis caused by what and what is the mode of entery and what is the immune defese like

A

affect internal organ + enter by skin of para nasal sinuses or lungs .
fungi causing this is : Histoplasma capulatum
Blastomyces dermatiditis
coccidiodes immitus

morphologicly dimorphic which mean both yeast and mold

cell mediatied immunity

21
Q

Clinical picture pf systemic mycosis

A

fungi have certin geographical distribution. associated with bat and bird dropping
wet areas and forest with decying wood .
more prevleant aroud lakes and rivers

and the clinical picture is chronic pneumonia . present with dry cough then progress to productue cough, hemopytsis and pleurtic chest pain . + pnemonic infiltrates in xray

22
Q

Name 4 opportunistic fungi

A

Yeast :
Candida albican
cryptococcus
Mold:
aspergillus
mucor

23
Q

watch page 35 for candida albicans picture

A
24
Q

Mucor morphology

A

Aseptate branching at 90 degree

25
Q

Mucor generally occur in what type of patient

A

immunocompromised host like those who have diabates

26
Q

They infect which part of body ?

A

para-nasal and the lower repiratory tract , even involving bone and can spread to brain

27
Q

Host risk factor of mucor 5

A

diabetes
neutropenia
sustined immunesuppressive therapy
chronic prednisone use
iron overload

28
Q

Rhinocerebral (sinus and brain )mucor in IC present with5

A

One sided facial pain!!
Headache!
nasal or sinus congestion !!
black lesion on upper side of mouth !!!!!!!!!!!!!!!
fever

29
Q

Pulmonary mucormycosis present with?4

A

fever
cough
cheast pain
shortness of breath

30
Q

The main line of innate host reponse to Mucor is 3

A

Neutrophil(PMNs)
Mononuclear cells MNCs
macrophhage

31
Q

Morphology of Cryptococcus ?

A

yeast resmbling candidia but has capsule

32
Q

capsule of cryptococcus can be staind by what

A

india ink prepartion

33
Q

Cryptococcus causes? and asscoicated with what kind of animal

A

Meniningitis
peumonia in IC

bird droping

34
Q

pneumocystis jiovecii causes what and clinical presention

A

pneumonia

Fever dry cough dyspnea cheast pain bilateral infltratin of lung

associated with cancer patient who went throw chemo

35
Q

pneumocystis jiovecii special feature

A

can exists in two form cyst and trophozoite so antibiotic is used

Micro (8 decks)

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