GIT Flashcards
both vomiting and diarrhea with a short incubation is characteristic of
staphylococcal aureus poisoning WHICH PRODUCE PREFORMD TOXIN
Cl.perfrengens WHICH PRODUCE PREFORMD TOXIN has both diarhea and vomiting but a
longer incubation period
which food caused vomting by bacillus cereus
rice WHICH PRODUCE PREFORMD TOXIN
diarrheas caused by staphlycoccus only in
cooked meat bacillus poisoning
Infection of small bowel non-inflammatory or minimal inflammation CAUSED BY which mecahnism
enterotoxin or adherence / superficial invasion
clinical sign of infection in small bowel and what we found in culture
Watery diarrhea
no fecal leukocytosis
Food poisoning (bacteria) name organisms and there morphology and in which food
1-Staphylococcus aureus G+ve cocci (two packets disease) diarrhea and vomiting also short incubation salad ,tuna fish
2-Bacillus cereus G+ve rod
Diarrhea form cooked meat
Vomiting (Emetic) form Rice
3-Clostridium perfringens G+ve rod diarrhea and little vomiting also longer incubation
4-Clostridium botulinum G+ve rod Botulism disease Flaccid Paralysis Canned food
Viral Gastroenteritis suggestive Features
- Mean incubation period of 24-48 hrs
- Mean duration of 12-60 hours
- Morethan 50% of affected persons have vomiting
no bacteria on culture
Common viruses for viral gastroenteritis
Rotavirus
Human caliciviruses (Noroviruses,Sapovirus)
Astrovirus
Enteric adenovirus
Pathogenesis for viral gastroenteritis
cause diarrhea by destroying or altering function of enterocyte at the villi but no in crypts
Villus cells are sodium-absorbing cells. See decreased sodium and water absorption
and reduced production of disaccharidases leading to carbohydrate malabsorption.
- Some also have proteins that stimulate fluid secretion
Similarities between norovirus and rotavirus
non inflammatory watery diarrhea + no wbc or blood
both seen in cooler months
differences between norovirus and rotavirus
Rota noro
Young adults
fever low grade fever
live oral vaccine no vaccine
rapid antigen assays cant work on it
differences between norovirus and rotavirus
Rota noro
Young adults
fever low grade fever
live oral vaccine no vaccine
rapid antigen assays cant work on it
Name an organism that can cause bacterial infection of small bowel
cholera
ecoli
morphology of cholera
gram negatiave rod
is cholera enterotoxin or exotoxin
enterotoxin
clinical presention , pathogenisis and mangament of cholera
rice water stool
A = Active —> go to cytosol and act on Gs supunit —-> increase cAMP——–> increase protein kinase which will ead to water and elcetrocyte loss
/
B binding
management if adequte water replacement
Ecoli morphology
G-ve bacillus (rod_
How dose ecoli handel ph and how dose it transmit
very sensitve to ph
transmmitted by contaminnated water
What are the types of E.coli that cause watery travelers diarrhea
Enterotoxigenic E.coli (ETEC)
Enteropathogenic E.coli
enteroaggregative E.coli
How dose ecoli cause watery diarrhea in small intestine
By
1-labile toxin —-> stimulate cAMP adenylate cyclase by ADP-ribosylatin;
2-stable toxin stimulates guanylate cyclase
Major pathogenic factor of bloody diarrhea by ecoli(hemolytic uemic syndrome ) and which organ and lap finding
Shiga toxin that inhibit protein synthesis in enterocyte by removing adenine from 28S ribosomal RNA
Large intestine
RBC IN STOOL
Organism that cause bloody diarrhea + gramnegtive rod in large bowel
E.coli
Shigella dysenteriae
Salmonella
campylobacter jejuni
Bloody diarrhea caused by ecoli have a toxin mediated toxin what is it and what the clinical picture of it in large intestine
enterohemorrhagic E.coli (shiga toxin)
dysentery lile picture with pain griping fever .
Blood and mucous + WBCs in stool
Enteroinvaseive E.coli
no blood
