Parasite Flashcards

1
Q

Congenital Toxoplasmosis

A

Deafness, Chorioretinitis, Hydrocephalus, Intracranial calcifications

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2
Q

How does Naegleria fowleri enter the body?

A

It enters via the cribriform plate and goes into the CNS

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3
Q

Associations of Naegleria fowleri

A

Freshwater
Water sports
Nasal irrigation systems and contact solution

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4
Q

Toxoplasmosis on CT/MRI

A

Ring enhancing lesions

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5
Q

Transmission of Toxoplasmosis

A

Cysts in undercooked meat

Oocysts in cat feces

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6
Q

Treatment for Toxoplasmosis

A

Sulfadiazine + Pyrimethamine

Prophylaxis in AIDS patients with CD4 count

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7
Q

Enlarged lymph nodes, recurring fever, somnolence, coma

A

African Sleeping Sickness caused by Trypanosoma brucei

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8
Q

Transmission of Trypanosoma brucei

A

Tsetse fly (painful bite)

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9
Q

Giardia associations

A

Camping

Mountain streams

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10
Q

Treatment for Giardia

A

Metronidazole

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11
Q

Pathogenicity of Giardia

A

Stimulates mucus production that impairs absorptive capacity of intestine

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12
Q

Trophozoites with RBCs in the cytoplasm

A

Entamoeba histolytica

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13
Q

Bloody diarrhea, liver abscess, RUQ pain

A

Entamoeba histolytica

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14
Q

Severe diarrhea in AIDS

A

Cryptosporidium

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15
Q

Each Cryptosporidium oocyst has….

A

4 sporozoites

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16
Q

Pathogenicity of Cryptosporidium

A

Sporozoites attach to intestinal wall causing diarrhea and small intestine damage

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17
Q

Treatment for Crytposporidium

A

Prevention - filtering water supplies
Nitazoxanide in immuncompetent hosts
Spiramycin

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18
Q

Vaginitis - Foul smelling, greenish discharge, itching and burning

A

Trichomonas - a flagellated protozoa (motile)

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19
Q

Strawberry cervix

A

Trichomonas

20
Q

Treatment for Trichomonas

A

Metronidazole for patient AND partner

21
Q

Disease caused by Trypanosoma Cruzi

A

Chagas disease

22
Q

Dilated cardiomyopathy with apical atrophy, megacolon, megaesophagus

A

Chagas disease

23
Q

Characteristic acute sign of Chagas disease

A

Romaña sign - unilateral periorbital swelling characteristic of acute stage

24
Q

Chagas vector

A

Reduviid bug (painless bite)

25
Diagnosis of Chagas disease
Blood smear
26
Treatment for Chagas disease
Benznidazole or Nifurtimox
27
Leishmania donovani disease
Visceral leishmaniasis
28
Spiking fevers, hepatosplenomegaly, pancytopenia in person from South America, Africa or Middle East
Visceral leishmaniasis
29
Transmission of Leishmaniasis
Sandfly
30
Diagnosis of Leishmaniasis
Macrophages containing amastigotes
31
Where does Leishmania donovani multiply? Symptoms because of that?
Multiplies in the reticuloendothelial system; causes pancytopenia, hepatosplenomegaly, fevers`
32
Leishmania braziliensis
CUTANEOUS Leishamaniasis (erythematous papule that expands and boils)
33
Treatment for Leishmaniasis
``` Amphotericin B Sodium Stibogluconate (for cutaneous) ```
34
Intestinal Nematodes
``` Enterobius vermicularis - pinworm Ascaris lumbricoides - giant roundworm Strongyloides stercoralis Necator americanus, Ancylostoma duodenale - hookworms Trichinella spiralis ```
35
Intestinal infection causing anal pruritis (diagnosed by seeing egg via tape test)
Enterobius vermicularis (pinworm)
36
Intestinal infection with possible obstruction at ileocecal valve (blood --> lung --> GI)
Ascaris lumbricoides
37
Transmission of Strongyloides stercoralis
Larvae in soil penetrate the skin
38
Transmission of Necatur americans, Ancylostoma duodenal
Larvae penetrate the skin
39
Intestinal infection causing vomiting, diarrhea, epigastric pain (may feel like peptic ulcer)
Strongyloides stercoralis
40
Auto infects itself --> larvae hatch from eggs laid in the intestinal wall and repenetrate wall, enter blood stream
Strongyloides stercoralis
41
NO eggs in stool, only larvae
Strongyloides stercoralis
42
Intestinal infection causing ANEMIA by sucking blood from intestinal walls
Necator americanus, Ancylostoma duodenale
43
Transmission of Trichinella spiralis
Fecal-oral; undercooked pork
44
Intestinal infection; larvae enter bloodstream and encyst in STRIATED muscle cells --> inflammation of muscle
Trichinella spiralis
45
Fever, vomiting, nausea, PERIORBITAL EDEMA, MYALGIA
Trichinella spiralis
46
Mechanism of Bendazoles
Microtubule inhibitors - they might cause more obstruction with Ascaris and DON'T GIVE to pregnant women (Pyrantel pamoate instead)