Paraneoplastic syndromes affecting nervous system Flashcards

1
Q
  • Assoc. with small cell lung cancer (also breast and ovarian)
  • Ab directed against pre-synaptic voltage gated calcium channel in the peripheral nervous system
A

Lambert-Eaton Syndrome

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2
Q
  • Assoc. with small cell lung cancer and neuroblastomas
  • Sensory neuropathy - may be painful
  • cerebellar syndrome
  • encephalomyelitis
A

Anti-Hu

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3
Q

Associated with ovarian and breast cancer
cerebellar syndrome

A

Anti-Yo

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4
Q

associated with breast, colorectal and small cell lung carcinoma

stiff person’s syndrome or diffuse hypertonia

A

Anti-GAD antibody

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5
Q

associated with breast and small cell lung carcinoma

ocular opsoclonus-myoclonus

A

Anti-Ri

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6
Q
A
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