Papilomavirus Flashcards

1
Q

Célula afectada de papilomavirus

A

Queratinocitos

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2
Q

Verrugas

A

Consecuencia de estímulo vírico de crecimiento celular y engrosamiento de estratos basal, espinoso y granuloso
Proliferación benigna de resolución espontánea

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3
Q

Coilocitos

A

Queratinocitos hipertrofiados con halos transparentes que rodean los núcleos arrugados

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4
Q

Oncogenes

A

E5, E6 y E7 del VPH-16 y el VPH-18

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5
Q

Oncogen E5

A

Favorece crecimiento celular

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6
Q

Oncogen E6 y E7

A

Evitan función de proteínas supresoras

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7
Q

Papilomas laríngeos

A

Tumores epiteliales benignos más comunes de la laringe
VPH-6 y VPH-11

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8
Q

Carcinoma orofaringeo

A

Cáncer en orofaringe
VPH de alto riesgo VPH-16 y VPH-18

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9
Q

Verrugas anogenitales

A

Condilomas acuminados
En epitelio escamoso de genitales externos y región perianal
VPH-6 y VPH-11

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10
Q

Tratamientos

A

Extirpación de verrugas
Estimuladores de respuesta innata e inflamatoria
Cidofovir
Vacunas

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11
Q

Tratamiento con estimuladores de respuesta innata e inflamatoria

A

Imiquimod e interferón
Favorecen curación rápida

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12
Q

Cidofovir

A

Erradicación selectiva de células infectadas
Induce apoptosis por inhibición de ADN polimerasa

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13
Q

Vacunación

A

Vacuna nonavalente (VPH-6, 11, 16, 18, 31, 33, 45, 52 y 58)

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