Paper3: Aggression Flashcards
- Neural Mechanisms of Aggression
What is the difference in hot- and cold-blooded aggression?
And the case studies assossiated with these
Hot (reactive aggression): an impulsive behavior coupled with physiological arousal
- Case:Tony Martin shot 3 intruders, killed one (a 16 year old) following burglaries at his home. Initially, sentenced to life imprisonment.
Cold: a premeditated way of getting what you want
- Rape and murder
- Case: the Moors Murders: Ian Brady and Myra Hindley
- Forensic psychology is primarily concerned with this type.
- Neural Mechanisms of Aggression
What are the brain regions associated with the limbic system?
Includes: Amygdala, hippocampus and thalamus/hypothalamus, OFC
- Neural Mechanisms of Aggression
What is a key role of the limbic circuit?
Maclean: limbic system in the mammalian brain is the centre of emotion and learning
Collection of structures in the centre of the brain.
One of its functions is to processes emotional responses Such as aggression.
- Neural Mechanisms of Aggression
What is the limbic circuit also known as?
Papez circuit as Papez first identified the contents of the limbic system
- Neural Mechanisms of Aggression
What are three key regions of the limbic system involved in aggression?
Orbital frontal cortex - controls executive function (decision making) which tries to control aggression produced by the limbic system.
Amygdala - linked to the production of aggressive behaviour, FMRI’s show increased activity during aggressive responses. (Gospic)
Hypothalamus - role in integrating and expressing emotional responses, it can trigger aggressive behaviours as part of the fight or flight response.
- Neural Mechanisms of Aggression
What evidence is there for a role of serotonin in violent behaviour?
Animal studies:
What is the link between Kluver & Bucy’s (1937) research in animals and Kluver-Bucy syndrome
They discovered that the destruction of the amygdala in a dominant monkey caused it to lose social dominance.
Klüver-Bucy Syndrome, a rare neuropsychiatric disorder from bilateral temporal lobe lesions (affecting the hippocampus and amygdala), leads to symptoms like placidity.
An amygdala-lesioned animal immediately grabbed a grape near a rubber snake (A) and then explored the snake (B), behavior atypical in normal animals, which avoid snakes entirely.
- Neural Mechanisms of Aggression
What did Mark & Ervin (1970) report in a patient receiving stimulation to her amygdala?
Stimulation near the amygdala produces fear, anxiety, defensive, and sometimes violent behaviour.
found a woman receiving painless stimulation to her amygdala became enraged and smashed her guitar against the wall
- Neural Mechanisms of Aggression
Explain the research by Gospic et al. (2011), and how it sheds light on the role of the limbic system in aggression.
Participants played The Ultimatum Game, with Subject A as the Proposer and Subject B as the Responder. Subject B experienced mild provocation.
MRI scans revealed increased amygdala activity when Subject B rejected offers. However, taking benzodiazepines, which reduce anxiety, halved rejections and lowered amygdala activity, suggesting a link between reactive aggression and amygdala function.
- Neural Mechanisms of Aggression
Explain the relationship between serotonin and aggression.
- Serotonin has inhibitory effects on the brain - slowing down neuronal activity
- Aggression in humans and animals is associated with low levels of serotonin
- Normal levels in the OFC reduce the firing of neurons and allow for a greater degree of behavioural self control
- Decreased levels disturb this mechanism reducing self control and increasing impulsive behaviour including aggression
- Neural Mechanisms of Aggression
What evidence is there for a role of serotonin in violent behaviour?
1. Animal Studies
pharmacologically blocking or genetically modifying 5-HT2A receptors.
mice with a deletion of the gene responsible for 5-HT2A expression exhibit less aggressive behaviour compared to typical mice. Stimulation this receptor subtype can lead to aggression, especially when the animal perceives threat or competition
- Neural Mechanisms of Aggression
What evidence is there for a role of serotonin in violent behaviour?
- Anti-psychotics
drugs for schizophrenia block the D2 receptor but some impacts on other receptors. Risperidone and Olanzapine block the 5-Ht2A receptor, and has been shown to reduce aggression in patients with schizophrenia or dementia
- Neural Mechanisms of Aggression
What evidence is there for a role of serotonin in violent behaviour?
- Serotonergic Metabolites
Virkunnen compared levels of serotonin breakdown product (5-HIAA) in the cerebrospinal fluid of violent impulsive and non-impulsive offenders. The levels were significantly lower in the impulsive offenders because the reduction of the 5-H1AA means there’s decreased serotonin activity which effects the control of impulsive (reactive) aggression
So less serotgoneric metabolites so more serotonin levels in non-impulsive offenders.
- Neural Mechanisms of Aggression
What evidence is there for a role of serotonin in violent behaviour?
- Serotonin-Depletion Studies
Passamonti used acute tryptophan depletion (ATD) to temporarily lower serotonin levels by reducing tryptophan, serotonin’s precursor. Results showed ATD decreased connectivity between the PFC and amygdala when participants viewed angry faces, suggesting low serotonin may impair the PFC’s regulation of the amygdala’s aggression-related responses.
- Neural Mechanisms of Aggression
What evidence is there for a role of serotonin in violent behaviour?
5. Post-Mortem Studies
Rosell and Siever reviewed post moretem studies indicating that individuals with histories of impulsive aggression show an upregulation of 5-HT2A receptors (perhaps compensating for low serotonin) in the PFC, particularly in the OFC.
- Neural Mechanisms of Aggression
2 strengths and 1 limit
P: A strength of the limbic system’s involvement in aggression is case study evidence showing that damage to it can lead to aggressive behaviors.
Eg: Burns & Swerdlow reported a case where pedophilia developed after a tumor in the orbitofrontal cortex, resolving after surgery.
Ex: Similarly, Sumer’s case of a 14-year-old girl’s extreme aggression was linked to a tumor pressing on her amygdala.
C: However, case studies may not be generalizable, and it’s important to identify the specific amygdala connections affected.
L: Overall, while case studies support the link between limbic activity and aggression, they should be interpreted with caution and corroborated by other research.
P: A strength of the serotonin explanation for aggression comes from drug research showing that increasing serotonin reduces aggression.
Eg: Berman (2009) found that participants given paroxetine (boosting serotonin) gave fewer and less intense shocks in a lab game, especially those with a history of aggression.
Ex: This suggests increased serotonin reduces aggression in a controlled setting, providing evidence beyond correlational studies.
C: However, the lack of direct measures of serotonergic activity limits interpretation, as it’s unclear if the reduction in aggression is due to serotonin or other effects of paroxetine.
L: These findings don’t conclusively establish a causal link between serotonin and aggression so may lower the internal validity. Future studies should use neuroimaging or biochemical assays to measure serotonin receptor activity.
P: A limitation of research on the neural basis of aggression is that much of it is correlational, limiting causality.
Eg: Correlational studies are often necessary due to ethical constraints, as directly provoking aggression would risk harm to participants. Researchers rely on brain scans to observe links between aggression and brain structures like the amygdala or OFC.
Ex: However, without experimental manipulation, it’s unclear if changes in these areas cause aggression or result from it.
L: This raises the possibility of a third variable, such as fluctuating neurotransmitter levels, influencing both aggression and neural changes. Consequently, the correlational nature limits conclusions about causality so lowers the internal validity
- Hormonal mechanisms of aggression
What is androgen?
A male sex hormone responsible for masculine features eg: testosterone
- Hormonal mechanisms of aggression
Suggest 3 reasons why testosterone is thought to have a role in aggression in males.
males are generally more aggressive than females
-testosterone has a role for regulating social behaviour via its influence on the brain implicated with aggression
-Daly and Wilson: Aggression is highest in males 20+ years old when testosterone peaks
- Hormonal mechanisms of aggression
What animal data (causation) support the role of testosterone in aggression?
Giammanco: experimental increases in testosterone increased aggression and the removal of testes decreased aggression
- Hormonal mechanisms of aggression
What did Dolan et al.’s (2001) study find with regard to testosterone and aggression?
positive correlation between testosterone levels and aggression in 60 male offenders in UK maximum security hospitals. The men mostly had personality disorders and a history of impulsive (reactive) violent behaviour
- Hormonal mechanisms of aggression
What evidence is there for the role of hormones in female aggression?
progesterone plays a role in aggression in women
Levels of progesterone vary during ovulation cycle are lowest after menstruation
Ziomkiewick found a negative correlation between progesterone and aggression in women
- Hormonal mechanisms of aggression
1 strength and 1 limit
P: A strength of the hormonal explanation of aggression is supporting empirical evidence.
Eg: Mehta and Josephs (2006) measured testosterone levels before and after a competitive game loss. Following the loss, 73% of those with increased testosterone chose to re-challenge the winners (operationalized as aggression), compared to only 22% of those whose testosterone levels decreased.
Ex: This highlights that increased testosterone after a status loss can lead to more aggressive actions, supporting its role in context-dependent aggression.
Cou: The study implies a narrow definition of aggression, as real-world aggression includes verbal and physical confrontations, which may not be fully captured here.
L: Thus, while testosterone may influence aggression in competitive contexts, its effect might differ in more diverse social situations.
P: A limitation of the explanation that increased testosterone levels increase aggression is that it seems incomplete.
Eg: Carre and Mehta (2011) proposed the dual-hormone hypothesis, which suggests high testosterone only promotes aggression when cortisol levels are low. When cortisol is high, it inhibits testosterone’s effect on aggression.
Ex: Explaining aggression through a single hormone may be overly reductionist, as multiple hormonal and social factors interact to influence behavior.
L: This limits the validity of testosterone-based explanations, as it overlooks cortisol’s moderating role. A more nuanced, multi-hormone approach, accounting for environmental factors, may better reflect the biological basis of aggression.
- Genetic factors of aggression
What are the 4 broad approaches to the study of the influence of genetics and environment on behaviour (such as aggression)
1) twin studies
2) adoption studies
3) candidate studies
4) family studies
- Genetic factors of aggression
Explain the rationale for twin studies
- MZ twins share all their genes, so differences between them are assumed to be due to environmental factors.
- If both MZ twins are highly aggressive, it suggests a genetic influence.
- The degree of similarity between twins on a trait is called the concordance rate.
- Concordance rates measure the presence of the same trait in both members of a twin pair.
- These rates are often compared with DZ twins, who are 50% genetically related.
- Higher concordance rates in MZ twins suggest a heritable component to the trait being measured.
- Genetic factors of aggression
What did Coccaro et al. (1997) show in their twin studies
Studied aggressive behaviours (Physical assault) in adult twins
He found that MZ twins had concordance rates of 50% and DZ at 19% suggesting because MZ twins share the same DNA there’s certainly a genetic component to aggression and DZ twins share only 50% of their DNA
Verbal aggression was also 28% in MZ and 7% DZ.
- Genetic factors of aggression
How is this study different than other twin studies that have looked at the influence of genetics on aggression?
- A child is biologically related to their biological parents (genetic component) and shares an environment with adoptive parents (environmental component).
- Higher concordance with adoptive parents suggests the trait is influenced by the environment.
- Higher concordance with biological parents suggests a genetic component to the trait.
- Genetic factors of aggression
Describe the findings of 2 studies that have examined the role of genetics on aggressions using adoptions.
Rhee and Waldman: Conducted a meta-analysis of adoption studies on aggression and antisocial behavior, finding genetic influences accounted for 41% of the variance in aggression, similar to twin study findings.
Hutchings and Mednick: Studied 14,000 adoptions in Denmark and found a higher incidence of criminal convictions in adopted boys whose biological fathers had criminal records. However, criminal convictions don’t always indicate aggression, limiting internal validity.
- Genetic factors of aggression
Which gene has been implicated in aggression, and what is the mechanism thought to be?
Monoamine Oxidase A (MAOA gene)
-controls production of MAO-A enzyme
-this enzyme regulations the metabolism of monoamines – breaks these down
- Genetic factors of aggression
Which allele of the gene has been associated with aggression?
The MAOA-L (low activity allele) – called the warrior gene - results in low activity of the MAO-A enzyme
This gene has been linked to high levels of aggression.
Which contradicts previous research which shows low levels of serotonin is associated with high aggression not high levels of serotonin.
- Genetic factors of aggression
Which neurotransmitters does the MAO enzyme metabolise (break down)?
Monoamines – serotonin, dopamine, noradrenaline
- Genetic factors of aggression
Explain the relationship between a dysfunction of the gene that codes for the enzyme, and the levels of each of these transmitters and how this impacts behaviour.
Low activity allele of a gene produces less or low activity of a protein eg: enzyme
Less enzyme being synthesised means less neurotransmitter is broken down/metaboised so means there’s higher levels of neurotransmitter at the synapse.
- Genetic factors of aggression
Why is this referred to a the ‘warrior gene’?
MAOA has been dubbed the “warrior gene” because the low-activity variant is more common in populations with a history of warfare, with 2/3 of these populations carrying the low-activity version.
Lea and Chambers (2007) found that 56% of New Zealand Maori men carried the MAOA-L variant, compared to 34% of Caucasians. Maori people are known for their warrior culture.
- Genetic factors of aggression
How did Brunner et al’s(1993) study implicate the MOAO-L gene variant in aggression?
Brunner et al (1993) studied a Dutch family in which 28 of the males behaved very aggressively and violently (e.g. rape, attempted murder and assault).
These men were found to have abnormally low levels of MAO-A enzyme and the MAOA-L gene variant (sometimes referred to a Brunner Syndrome).
- Genetic factors of aggression
How did Stuart’s (2014) study suggest that the MAOA-L variant is implicated in aggression?
Found that of 97 men convicted of intimate partner violence (IPV) those with the MAOA-L variant gene were the most violent perpetrators and this resulted in the worst injuries on their partners.
- Genetic factors of aggression
4: environmental interactions
How did Caspi et al. (2000) suggest that there may be a gene x environment interaction with MAOA-L?
The MAOA-L gene is linked to adult aggression only when combined with traumatic life experiences, as explained by the diathesis-stress model.
Studied of 500 male children found that those with MAOA-L were more likely to behave antisocially if mistreated as children. However, children with MAOA-H or those with MAOA-L who were not mistreated did not show antisocial behavior. This combination of genetic vulnerability and environmental stress leads to aggression. These findings were also replicated by Frazzetto et al. (2007).
- Genetic factors of aggression
1 strength
A strength of the genetic explanation for aggression is the empirical support for its heritability.
Eg: Rhee & Waldman (2002) conducted a meta-analysis of twin and adoption studies, finding that genetic factors account for 41% of aggression variance, suggesting a substantial hereditary influence.
Ex: This implies that aggression is partly genetic, reflecting a diathesis-stress model.
C: However, the 41% variance highlights the role of other factors, such as family dynamics and social experiences, which interact with genetic predispositions.
L: This approach is valid as it considers both genetic and environmental influences, aligning with evidence that aggression results from their complex interplay.
- Genetic factors of aggression
2 limitations of the genetic explanation
of aggression
P: difficulty measuring the effects of genetics alone and separating them from the environment.
Eg: McDermott (2009) found that participants with MAOA-L behaved aggressively in a money-allocation experiment only when provoked; otherwise, they acted similarly to MAOA-H participants.
Ex: This suggests aggression is better explained by an interactionist approach, where both genetic vulnerability (MAOA-L) and environmental factors (provocation) interact, complicating measurement.
L: While the diathesis-stress model explains this interaction, it doesn’t clarify the relative contribution of genetics and the environment, undermining the validity of a purely genetic explanation.
P: there are likely to be multiple genes involved in aggression which makes it difficult to research.
Eg: Stuart (2014) found that intimate partner violence in men was associated with both the MAOA-L gene and the serotonin transporter gene (5-HTT), with the combination of both being most linked to IPV.
Ex: This indicates that isolating one gene is reductionist. Research is increasingly focusing on multiple genes; Vassos (2014) found no association between a single gene and aggression, while Tielbeek (2018) identified 40 genes linked to aggression in a study of 30,000 individuals.
L: This challenges the idea that a single gene causes aggression, questioning the validity of a one-gene explanation.
Moral-l less of it to break down serotonin so higher levels of seoritin but 5htt reuptake presynaptic neuron So low levels of serotonin as they’re assossiated with High levels of aggression
4 - Ethological Explanation of Aggression
What is Lorenz’s definition of aggression
‘the fighting instinct in beasts and man that is directed against members of the same species’
4 - Ethological Explanation of Aggression
What assumptions does Lorenz make that make the study of aggression in animals relevant to that in humans?
- Aggression is an instinct. It occurs in all members of a species without the need for learning. It is innate and mostly genetically determined.
- We can study non-human animals and extrapolate to humans because we are all subject to the same laws of natural selection.
4 - Ethological Explanation of Aggression
What is meant by an ‘adaptive’ behaviour?
refers to behavior that enables a person to get along in his or her environment with greatest success and least conflict with others.
- Help survival
- Protect resources (land/food)
- Establish dominance hierarchies
- Access to females
4 - Ethological Explanation of Aggression
Give 2 reasons why aggression may be adaptive
Ethological explanations suggest that the main function of aggression is adaptive.
Adaptive Function 1:
After an aggressive encounter, the loser is not killed but forced to move, reducing competition for resources by spreading individuals across an area.
Adaptive Function 2:
Aggression helps form a dominance hierarchy, which offers benefits like mating rights and reduces future aggression once established.
4 - Ethological Explanation of Aggression
What is a dominance hierarchy, and why might it be adaptive?
Many species establish dominance hierarchies through aggressive, often ritualized interactions, suggesting this behavior is adaptive.
Doves, as non-hunters, lack this inhibition but can simply fly away to avoid conflict.
Lorenz believes humans, like doves, are naturally inclined to avoid aggression but, with the ability to develop weapons of mass destruction, lack instinctive inhibitions.
4 - Ethological Explanation of Aggression
What evidence is there of dominance hierarchies in humans?
Pettit et al (1988) studied play groups of young children and observed that aggressive interactions were an important aspect of how some children gain dominance over others.
4 - Ethological Explanation of Aggression
What is a ritual?
A series of behaviours carried out in a set order.
4 - Ethological Explanation of Aggression
What does ritualistic aggression typically comprise in animals?
Most aggressive interactions consist of ritualistic signalling (snarling, displaying claws, pushing contests) and rarely becomes physical.
4 - Ethological Explanation of Aggression
What did Lorenz (1966) note about aggression in animals?
Lorenz (1966) observed that in fights between animals, actual injury is rare. Because the adaptive value is to warn off the lower ranking animal by being aggressive beforehand
4 - Ethological Explanation of Aggression
What is an appeasement display, and what is their purpose?
Lorenz (1966) observed that in fights between animals, actual injury is rare.
suggested that in intra-species, aggressive confrontations end with a ritual appeasement display to indicate the acceptance of defeat and stop any further aggression from the victor to preventing actual injury
Adaptive because if aggressive encounters ended with injury or death it could threaten the existence of the species.
4 - Ethological Explanation of Aggression
What was Schenkel’s (1967) opposing view to Lorenz view on appeasement signals?
Lorenz suggested that the wolf showing its jugular vein is an appeasement signal.
argues against this view and suggests that this ‘submissive’ pose is actually a challenge that leads to further fighting.
4 - Ethological Explanation of Aggression
What is an Innate Releasing Mechanism (IRM)?
A biological structure or process which is activated by an external stimulus, in turn triggers a fixed action pattern.
4 - Ethological Explanation of Aggression
What is a fixed action pattern (FAP)?
These are a sequence of stereotyped pre- programmed behaviours triggered by an innate releasing mechanism.
Stimulus -> IRM -> FAP
4 - Ethological Explanation of Aggression
What are the 6 main features of FAPs, according to Lea (1984)?
- Stereotyped (unchanging sequence)
- Universal within the species
- Unaffected by learning
- ‘Ballistic’ (once started they must continue)
- Single Purpose - only occurring in one type of situation
- A response to an identifiable and specific stimulus - called a releaser if intra-specific