Paper 2: Topic 6: Biopsychology Flashcards
What are the 5 divisions of the nervous system
- The Central Nervous System
• Brain (centre of conscious awareness) & Spinal Cord (reflex actions)
• Coordinates incoming sensory information and sends instructions to other parts of the NS
• Cerebral cortex comprises grey and white matter - The Peripheral Nervous System
• Network of nerve fibres (axons) that connects parts of the body with the CNS
• Transmits messages from the CNS to muscles/glands - The Somatic System
• Conscious movement; myelination enables rapid transmission; reflex arc - The Autonomic Nervous System
• Involuntary bodily functions (eg breathing, heartbeat)
• Transmits information between organs; not as fast (unmyelinated) - Sympathetic & Parasympathetic Nervous System
• Fight or flight (sympathetic) and rest & digest (parasympathetic)
What’s the nervous system
The body’s main communication system which is very fast acting.
• It is a complex network of specialised nerve cells (neurons) which pass information around the body using electrical signals and chemicals (neurotransmitters).
What are the 2 divisions of the human nervous system
The central nervous system
The peripheral nervous system
What’s the 2 subdivisions of the peripheral nervous system
The autonomic nervous system
The somatic system
What’s the 2 subdivisions of the autonomic nervous system
Sympathies division
Parasympathetic division
What’s the central nervous system
Brain - centre of conscious awareness
Spinal cord - reflex actions
Function of the central nervous system
-Coordinates incoming sensory information and sends instructions to other parts of the NS.
-This is our store of knowledge and habits.
Structure of the central nervous system
Made up of the brain and spinal cord
• The brain is the centre of conscious awareness
• The cerebral cortex (3mm outer layer) is highly developed in humans and distinguishes our higher mental functions from other animals
• The spinal cord is an extension of the brain. It is responsible for reflex actions
Describe the cerebral cortex of the central nervous system
Outer layer of the brain
Cerebral cortex is also known as grey matter due to the colour of it.
Grey matter is made up of cell bodies.
The white matter is made up of axons which form fibre tracts
Structure of the peripheral nervous system
-made up of a Network of nerve fibres (axons) which are connected to the CNS
-it sends info to the CNS from the outside world and transmits messages from the CNS to muscles and glands (effectors) in the body
Describe the somatic nervous system of the peripheral nervous system
-controls conscious movement as it sends instructions from CNS to effectors in muscles and glands
-transmits info from receptor cells in sense organs to the CNS (takes info from external environ.)
-needs to act quickly as it’s made up of myelinated neurons
Describe the reflex arc of the somatic nervous system
1) stimulus detection: sensory receptor detects a stimulus
2) sensory neuron activation: The sensory receptor sends an electrical impulse along a sensory neuron towards the central nervous system (CNS), typically the spinal cord.
3) relay neuron: In the spinal cord, the action potential reaches an integration centre (usually a synapse) between the sensory neuron and a motor neuron or an interneuron, which then relays the signal.
4) motor neuron activation: The impulse is transmitted to a motor neuron. The motor neuron carries the signal away from the CNS to an effector.
5) effector response: The effector, which is usually a muscle or gland, produces a response. For instance, in the hot object scenario, the effector would be the muscles in your arm, causing you to withdraw your hand quickly
Describe the pathway of the somatic nervous system
Stimulus -> sensory neuron -> relay neuron -> motor neuron -> effector (muscle/gland)
Function of the autonomic nervous system
-controls involuntary boldly functions which aren’t consciously directed eg: breathing, heartbeat, digestive processes and sexual arousal
-only transmits info to and from internal bodily organs (don’t need sensory pathways)
-acts more slowly than the SNS (somatic) and therefore made of unmyleinated nerve fibres
- divided into sympathetic and parasympathetic nervous system
Describe the sympathetic divisions of the autonomic nervous system
works with the endocrine system (comprising glands & hormones) to get the body prepared for fight or flight
Describe the parasympathetic divisions of the autonomic nervous system
works with the endocrine system to return the body to its normal resting state (rest and digest).
Brief:
What does the PNS system consist of and function
Network of nerve fibres
Connects parts of the body with CNS
Brief:
What does the ANS system consist of and function
Network of unmyelinated nerve fibres (slower acting)
Controls the automatic functions of the body e.g. breathing, heart rate Connects the senses and the organs with the CNS
Concerned with emotions, threats and bodily changes
Brief:
What does the SNS system consist of and function
Network of myelinated sensory and motor neurons (quicker acting)
Controls the conscious movement e.g. reflex of touching a hot pan
Carries sensory information from the outside world and internal organs to the CNS (sensory neurons)
Carries instructions for movement from the CNS (motor neurons)
What’s the function of the spinal cord
Responsible for reflex actions
Ensures signals from the brain are transmitted to the rest of the body through the Peritheral nervous system
2: Structure and functions of neurons
What is a neuron?
Specialised nerve cells which are part of the nervous system
80% of neurons are located in the brain and 20% are in the spinal cord, peripheral nervous system, and the gut (gut brain axis)
2: Structure and functions of neurons
How do neurons transmit info?
electrically (through action potentials)
chemically (using neurotransmitters)
2: Structure and functions of neurons
What do all neurons consist of?
Cell body, dendrites, mylien sheath, axon, nodes of ranvier
Dendrites receive signals; action potentials propagate the signal down the axon to the axon terminal, stimulating the release of neurotransmitters
2: Structure and functions of neurons
What are dendrites and what do they do?
Dendirtes protrude (stick out) from the cell body, these carry nerve impulses (action potentials) from neighbouring neurons towards the cell body
2: Structure and functions of neurons
What is the function of the cell body?
Includes a nucleus which contains the genetic material of the cell
Also called the Soma
2: Structure and functions of neurons
What is the axon?
Carries action potential away from the cell body down the length of the neuron. It’s covered in a myelin sheath that protects the axon and speeds up electrical transmission of the action potential
2: Structure and functions of neurons
What is the axon terminal and myelin sheith
Protrude from the axon and form synapses with the dendrites of the neighbouring neuron
Covers the axon, protects the axon and speeds up electrical transmission of the impulse
It’s segmented by gaps called nodes of ranvier which speed up the transmission by forcing it to ‘jump’ across the gaps along the axon
2: Structure and functions of neurons
What disease results from degeneration of the myelin sheath?
Multiple Sclerosis. A chromic autoimmune disorder where the immune system attacks the myelin sheath in the CNS, including the brain and spinal cord, causing slowing of neurotransmissiom, resulting in symptoms like fatigue, numbness, weakness, vision problems, difficulty with coordination and balance and cognitive issues
2: Structure and functions of neurons
Describe the neuron pathway
Stimulus -> sensory neurons -> relay neurons (in brain) -> motor neuron -> response
Sensory input -> integration -> motor output
2: Structure and functions of neurons
What size dendrites and axons do sensory neurons have?
Sensory neuron – afferent (incoming to the brain) neurons
Long dendirtes and short axons. Cell Body is in the middle of the spinal cord.
2: Structure and functions of neurons
Function of sensory neuron
Take sensory information from the environment (pocked with a needle) and sends signals to the brain and convert a specific type of stimulus by their receptors into action potentials
2: Structure and functions of neurons
Do all messages go to the brain from sensory neurons
No. Some end in the spinal cord to allow reflex actions to occur quickly without the delay of sending impulses to the brain
2: Structure and functions of neurons
What size dendrites and axons do motor neurons have?
Efferent (outgoing) neurons
Short dendrites: connect to axons of relay neurons
Long axons: to connect to effector organs
2: Structure and functions of neurons
Function of motor neurons
Take messages from the CNS to effectors like glands and muscles
2: Structure and functions of neurons
Where is its cell body and axon located in motor neurons?
n the spinal cord
Fibre (axon) projects outside the spinal cord to directly or indirectly control effector organs
2: Structure and functions of neurons
What size dendrites and axons do relay neurons have?
Interneuron Neurons
Short dendrites and short axons – as they don’t have to span long distances and aren’t myelinated
2: Structure and functions of neurons
What is the function of relay neurons
Connect sensory neurons to the motor or other relay neurons
Allow motor neurons and sensory neurons to communicate with eachother
Found only in the brain and spinal cord. Make up 97% of all neurons
2: Structure and functions of neurons
Give an example of when relay neurons are used in the reflex arc
Patellar reflex
Reflex arc:
1) Stimulus detection: sensory receptor detects a stimulus
2) Sensory neuron activation:
3) Relay neuron:
4) Motor neuron activation:
5) Effector response:
2: Structure and functions of neurons
Describe the human connectors project
Sensory receptors synapses with inter neuron in spinal cord. Inter neuron synapse with motor neuron which causes contract in quadriceps so leg move
2: Structure and functions of neurons
Define the nodes of ranvier
Gaps between the myelin sheath which speed up transmission by making by action potential ‘jump’ across the gaps along the axon
3: synaptic transmission
What is the process of synaptic transmission?
one neuron communicates with another by releasing neurotransmitters to diffuse across the synapse
Electrochemical transmission of nerve impulses through infra-neuronal propagation of action potentials and inter-neurornal release of neurotransmitters that bind to post-synaptic receptors, affecting the electric charge of the post-synaptic neuron and prosperity to fire and an action potential
3: synaptic transmission
Explain what the synapse is.
The gap between the presynaptic neurons axon terminal and the post synpaic neurons dendrites/cell body where neuronal communication continues via release/uptake of neurotransmitters that diffuses across the gap
3: synaptic transmission
How does a neurotransmitter work?
How neurons communicate chemically
1) The electrical signal arrives at the axon terminal of the presynaptic neuron, the neurotransmitter to be released over supposed
2) Neurotransmitters bind to completely Receptors on the post synaptic neuron
3) This activation of the receptor determines whether the post-synaptic neuron will generate an alectrical signal
3: synaptic transmission
Explain how an action potential works
(Electrical impulse)
When a neuron is in a resting state, it’s negatively charged compared to the outside
When a neuron is activated by a stimulus, if this causes to become more positively charged it caused an action potential to travel down the axon
3: synaptic transmission
How does an action potential cause release of a neurotransmitter?
1) Action potential travels along the axon to the axon terminal of the presynaptic neuron
2) This triggers the vesicles to migrate towards and bind to the presynaptic memebrane and release neurostamnsitters
3) Neurotransmitters diffuse across the synapse and bind with the post synpaic receptors like a lock and key
3: synaptic transmission
Name 4 neurotransmitters
Adrenaline – right or flight
GABA – claiming, reduces anxiety (links to benzodiazepines for treating OCD) – inhibitory
Noradrenaline – concentration
Dopamine – pleasure
3: synaptic transmission
Explain how excitation works, and what is an EPSP?
Excitatory effects facilitate the firing of action potentials, promoting alertness and activity, if a neurotransmitter is excitatory , it leads to the generation of a excitatory postsynaptic potential (EPSP) leading to a positive charge at the postsynaptic membrane.
Makes the inside of the postsynaptic neuron less negitive compared to outside, moving the membrane potential closer to the threshold needed to trigger an action potmetial.
It’s more likely that the neuron will fire an action potential.
3: synaptic transmission
Explain how inhibition works, and what is an IPSP?
help to calm the mind and body and involved in inducing sleep.
When a neurotransmitter caused an inhibitory effect, it leads to the generation of an inhibitory postsynaptic potential (IPSP) leading to a negitive charge at the postsynaptic membrane.
Makes the inside of the postsynaptic neuron more negitive compared to the outside, moving the membrane potential further away form the threshold needed to trigger an action potential.
Making it less likely that the neuron will fire an action potential .
3: synaptic transmission
Explain temporal summation and spatial summation
Temporal: the combined effects of inputs over time
Spatial: the combined effects of inputs across multiple neurons
Summation:
A nerve cell can receive both EPSP and IPSPs at the same time
Summation is the net sum of the total IPSPs and EPSPs which determines whether or not the cell fires. The threshold is -60v for an action potential to be created.
4: endocrine system
What is the endocrine system?
A communication system that instructs glands to release hormones directly into the bloodstream which carry the hormones to the target organs (effectors). It works along side the NS to control vital bodily functions.
4: endocrine system
What speed does the endocrine system pass messages compared to the nervous system?
It acts slower than the NS but still has powerful effects
4: endocrine system
What is a hormone?
A chemical substance that circulates the bloodstream and affects target organs. Produced in large quantities.
They have a slower release but longer action than neurotransmitters
4: endocrine system
Label the diagram on the Cornell notes of the glands
.
4: endocrine system
What does the hypothalamus do?
Brain region connected to the pituitary gland.
Responsible for stimulating or controlling the release of hormones from the pituitary gland.
It’s the control system which regulates the endocrine system
4: endocrine system
What effects do hormones have?
Finish this.
4: endocrine system
What are the 2 adrenal gland regions?
-adrenal cortex (outside)
-adrenal medulla (inside)
4: endocrine system
What is released from the adrenal medulla gland and what impact does it have:
Secretes adrenaline and noradrenaline for the fight or flight response
4: endocrine system
What is released from the testes glands and what impact does it have:
Secretes testosterone which is responsible for the male sex charectaristics during puberty and muscle growth
4: endocrine system
What is released from the adrenal cortex glands and what impact does it have:
Secretes cortisol which stimulates the release of glucose to provide the body with energy whilst suppressing the immune system
4: endocrine system
What is released from the ovaries glands and what impact does it have:
Secretes oestrogen which regulates female reproductive system including menstral cycle and pregnancy
4: endocrine system
What is released from the pineal glands and what impact does it have:
Secretes melatonin which regulates sleep-wake cycle
4: endocrine system
What is released from the pituitary gland and what impact does it have:
Secretes Growth hormone, prolactin, ACTH, TSH, FSH, ADH, oxytocin
(The majority of hormones abreviated into capital letters are secreted by the pituary gland)
It’s the master gland that regulates other endocrine glands, controls growth, lactation, stress response (ACTH) and water balance (ADH)
5: fight or flight response
What is a gland?
Specialised organ that produces and secretes hormones, enzymes and fluids into the bloodstream
5: fight or flight response
What is a hormone?
A chemical messenger produced by glands that regulates various physiological processes in the body by affecting target cells or organs
5: fight or flight response
Name 8 major endocrine glands
Hypothalamus – part of CNS – connects to pituatory gland (the master gland)
Thyroid – metabolism
Testes – testostrione
Ovaries – oestorgen and progesterone
Adrenal glands – fight and flight
Pancreas – controls blood sugar
5: fight or flight response
Which two biological systems combine to implement the fight or flight response?
Endocrine system and nervous system, necessary to sustain arousal
5: fight or flight response
What phrase is used when talking about fight or flight?
‘Make the body prepared’
A sequence of activities within the body that are triggered when the body prepares itself for defending or attacking (fight) or running away to safety (flight)
5: fight or flight response
What’s the evolutionary origin of the fight or flight response
It’s our engrained survival instinct And represents the options our ancient ancestors could choose when dealing with dangerous environments
5: fight or flight response
Which brain region is involved in sensing danger, and what is the name of the pathway which is activated by it?
Amygdala
It’s assossiated with emotional processes and is the body’s ‘threat’ sensor
Part of the limbic system
If it alerts that there’s a threat then it will activate a sequence of events (the sympathomedullary (SAM) pathway)
5: fight or flight response
What are the steps of the activation of the SAM pathway?
Amygdala activates the SAM pathway -> Hypothalamus activates -> sympathetic nervous system triggers -> adrenal medulla ->releases/secretes adrenaline and noradrenaline facilitates -> fight or flight response
5: fight or flight response
In detail, what are the steps of the activation of the SAM pathway
1) The amygdala sends distress signals to the hypothalamus which activates the sympathetic branch of the autonomic nervous system (ANS)
- The ANS changes from resting state (parasympathetic) to the physiologically aroused (sympathetic)
2) This triggers the adrenal medulla to relase the stress hormone adrenaline into the blood stream
- Adrenaline triggers physiological changes in the body eg: increases heart rate which prepares the body for the fight or flight response
3) One the threat has passed the parasympathetic NS return sbody to its resting state and bodily functions (rest and digest). The parasympathetic NS and sympathetic NS work as an antagonistic pair; when one is activates the other isn’t. Eg: Heart rate and blood pressure return to resting level and pupils constrict, bladder control is regained and liver stored glucose in the form of glycogen for future use
5: fight or flight response
List 5 effects of the role of adrenaline
increase your heart rate: pushing blood to the muscles to enable action and to the brain to facilitate rapid response planning to prepare the body for action
-pupillary dilation: allows more light into eyes and to increase awareness of visual information to prepare the body for action
-breathing becomes more rapid to take in more oxygen to provide to the muscles to aid movement to prepare the body for action
-blood sugar (glucose) and fats are released into the bloodstream to provide energy to provide the body for action
-diversion of blood away from the digestive system to conserve energy by constricting blood vessels to provide the body for action
-increase in sweating: to cool your body
5: fight or flight response
Describe the involvement of the HPA Axis in the stress response
1) Detection of stress: when encountering a stressor (physical, emotional or psychological) the hypothalamus senses this and activated the HPA axis
2) Release of CRH: hypothalamus scope creates cortiotropin-releasing hormone (CRH) Into the blood, which travels to the pituitary gland
3) Release of ACTH: in response to CRH, the pituatory gland releases adrenocortiotropic hormone (ACTH) into the blood stream
4) Stimulation of the Adrenal glands: ACTH reaches the adrenal glands and stimulates the adrenal cortex to produce and release the hormone cortisol
5) Effects of cortisol: cortisol helps mobilise energy by increasing glucose in the bloodstream, enhancing brains use of glucose and increasing availability of substances that repairs tissue. It curbs functions thay would be nonessential in the fight ornfligh situation eg: growth, reproduction, digestion
6) Short term and long term effects: ST – enables te body to repsond to threats, but chronic activation can lead to impaired cognition and immunity and has been linked to anxiety, depression and weight gain
5: fight or flight response
Compare the HPA axis and the SAM pathway
HPA axis is activated more slowly (minutes to hours)m releasing cortisol
SAM pathway provides a more rapid and immediate response, releasing adrenaline
HPA Axis: cortisol hormone
SAM pathway: adrenaline hormone