PAPER 1 - Cardiovascular & Respiratory System Flashcards
Define SYSTEMIC CIRCUIT by filling in the gaps
Reponsible for the T——— of O———– B—- around the body from the L— V——- through A——- and A——– and returns D——— B—- to the R—– side of the heart through V—–
Reponsible for the TRANSPORT of OXYGENATED BLOOD around the body from the LEFT VENTRICLE through ARTERIES and ATERIOLES and returns DEOXYGENATED BLOOD to the RIGHT side of the heart through VEINS
Define PULMONARY CIRCUIT by filling in the gaps
D———— B—– leaves the R—– V——— to the L—– via the P———- A—— where it is then R——–with oxygen and returns to the L— side of the heart via the P——— V—
DEOXYGENATED BLOOD leaves the RIGHT VENTRICLE to the LUNGS via the PULMONARY ARTERY where it is then RESATURATED with oxygen and returns to the LEFT side of the heart via the PULMONARY VEIN
Define MYOGENIC
the capacity of the heart to generate its own electrical impulse, which causes the cardiac muscle to contract
Define DIASTOLE
the RELAXATION phase of cardiac muscle where the chambers fill with blood
Define SYSTOLE
the CONTRACTION phase of cardiac muscle where the blood is forcibly ejected into the aorta and pulmonary artery
Explain the Atrial Diastole Phase - 4 pointsto
- Atria fill with blood
- AV valves are closed
- Semi lunar valves are open
- Works together with Ventricular Systole
Explain the Ventricular Systole Phase - 4 points
- Pressure increases in the ventricle
- Ventricles contract
- Blood forced into the aorta and pulmonary artery
- AV valved forced to close as it works with Atrial Diastole
Explain the Atrial Systole Phase - 3 points
- Atria contract forcing blood into the ventricles
- AV valves open
- Semi lunar valves close
Explain the Ventricular Diastole Phase - 3 points
- Rising pressure in the atria causes the AV valves to open
- Ventricles fill with blood
- Semi-lunar valves close
Define CARDIAC OUTPUT
the volume of blood ejected from the left ventricle per minute.
Define STROKE VOLUME
the volume of blood ejected from the left ventricle per beat
How does VENOUS RETURN affect stroke volume?
- more blood to pump out
- greater venous return=greater stroke volume
How does ELASTICITY OF CARDIAC FIBRES affect stroke volume?
- greater the stretch = greater the contraction
- leads to an increase in SV
- AKA Starlings Law
How does CONTRACTILITY OF CARDIAC FIBRES affect stroke volume?
- greater force of contraction = increase in SV
- partly due to Ejection Fraction increase= % of blood activity actually pumped out of LV per contraction can go from 55% to 85%
Define HEART RATE
the number of times the heart beats per minute
What is the pathway of blood ? (VAVA ect)
vena cava right atrium (tricuspid valve) right ventricle pulmonary artery (lungs) pulmonary vein (bicuspid valve) left atrium left ventricle aorta (body)
What is the equation for cardiac output ?
HR x SV = Q
What is the CARDIAC CYCLE ?
Atrial Diastole
Ventricular Diastole
Atrial Systole
Ventricular Systole
What is the CONDUCTION SYSTEM ?
SA Node
AV Node
Bundle of HIS
Purkinje Fibres
Describe the SA Node
- Sinoatrial Node
- Specialised cardiac muscle fibres
- Located in the muscle walls of Right Atrium
- Acts as a pacemaker
Describe the AV Node
- Atrioventricular node
- Recieves impulse and delays passing it on
- Ensures atria contract before ventricles
Describe the Bundle of His
- Where the impulse arrives next via the septum
- In the middle of the chambers
Describe the Purkinje Fibres
- Via these the impulse is sent through the muscular walls of the ventricles
- Causing them to contract to force blood out
- at the bottom of the heart
Describe the structure of veins/venules
- Thin layer of smooth muscle
- Wider lumen
- Passes pocket valves
Describe the structure of pre-capillary sphincters
- Small ring of smooth muscle at the opening of the capillary bed
Describe the structure of capillaries
- Narrow diameter
- One cell thick
Describe the structure of arteries/arterioles
- Thick elastic walls
- Small lumen
- Smooth muscle layer
Describe the function of arteries/arterioles
- Carry blood away from the heart
- Essential to the redistribution of blood
Describe the function of capillaries
- Facilitate the exchange of gases and other nutrients between the blood and tissues
Describe the function of veins/venules
- Essential in the return of blood back to the heart
Complete this passage about the VASCULAR SHUNT MECHANISM
As we begin to exercise the distribution of B—– F— changes dramatically. Through V——– C—— and the S———- N——- S——, blood is diverted away from the non-essential T—— and O—– and redirected towards those which are active during exercise.
As we begin to exercise the distribution of BLOOD FLOW changes dramatically. Through VASOMOTOR CONTROL and the SYMPATHETIC NERVOUS SYSTEM blood is diverted away from the non-essential TISSUES and ORGANS and redirected towards those which are active during exercise.
Complete this process about what happens to the vascular shunt
At R— the P————- S——— are O— and the blood flows easily through them
During exercise the P————- S———– are C—— so blood flow bypasses the O—– and M—– to areas where it is M— N——
At REST the PRE-CAPILLARY SPHINCTERS are OPEN and the blood flows easily through them
During exercise the PRE-CAPILLARY SPHINCTERS are CLOSED so blood flow bypasses the ORGANS and MOVES to areas where it is MOST NEEDED.
Describe the function of pre-capillary sphincters
- Regulate blood flow back into the capillary bed
- Help the vascular shunt process
How do the CARDIAC CYCLE and the CONDUCTION SYSTEM work together?
Atrial Diastole Ventricular Diastole SA Node AV Node Atrial Systole Bundle of HIS Purkinje Fibres Ventricular Systole
Define AUTONOMIC
involuntary or unconscious
Define SYMPATHETIC NERVOUS SYSTEM
part of the autonomic nervous system responsible for increasing HR
Define PARASYMPATHETIC NERVOUS SYSTEM
part of the autonomic nervous system responsible for decreasing HR
Define MEDULLA OBLONGATA
a portion of the hindbrain that controls autonomic functions
Define CCC
Cardiac Contol Centre
Define HORMONAL
containing a hormone or hormones
Define VENOUS RETURN
the return of the blood to the right atria through the veins
Define ADRENALINE
a hormone secreted by the adrenal glands that increases rates of blood circulation, breathing, and carbohydrate metabolism and prepares muscles for exertion
Define FIRING RATE
the amount of neurons firing at a giving time
What are the 3 components of NEURAL FACTORS ?
chemoreceptors - increase in CO2
proprioreceptors - muscle and tendon movement
baroreceptors - blood pressure
What is the one component of HORMONAL FACTORS ?
adrenaline - increases HR
What are the components of INTRINSIC FACTORS ?
temperature
venous return
What are the 5 components in VENOUS RETURN ?
- pocket valve
- smooth muscle
- gravity
- skeletal muscle pump
- respiratory pump
What is RCC ?
Respiratory Control Centre
What are the 2 centres in the RCC ?
- expiratory centre
- inpiratory centre
What nerve is linked with the EXPIRATORY CENTRE and where does it go to ?
INTERCOSTAL NERVE - external intercostal muscles
What nerve is linked with the INSPIRATORY CENTRE and where does it go to ?
PHRENIC NERVE - diaphragm
What 3 components are in the VASCUALR SHUNT ?
- vasoconstriction
- vasodialation
- pre-capillary sphinter
What is VASOCONSTRICTION ?
when the lumen gets smaller - limiting blood flow
What is VASODIALATION ?
when the lumen gets bigger - increasing blood flow
What do PRE-CAPILLARY SPHINTERS do ?
open and close to allow blood to flow through capillaries
How does temperature link to venous return ?
temp increases - viscosity decrease - venous return increase - (SV) stroke volume increase = (Q) cardian output increase.
INSPIRATION REST active or passive ?
active
EXPIRATION REST active or passive ?
passive
INSPIRATION EXERCISE active or passive ?
active
EXPIRATION EXERCISE active or passive ?
active
What muscles are involved with IR ?
diaphragm
external intercostal
What muscles are involved with ER ?
none
What muscles are involved in IE ?
diaphragm
external intercostal
sternocleidomastoid
pectoralis minor
What muscles are involved in EE ?
internal intercostal
rectus abdominalis
IR : DIAPHRAGM
contracts and flattens
IR : RIBS
up and out
ER : DIAPHRAGM
relaxes
ER : RIBS
down and in
IE : RIBS
further up and out
EE : RIBS
forced down and in
IR : RESULT
decrease in pressure in THORATIC CAVITY
air is brought into the lungs
ER : RESULT
increase in pressure in THORATIC CAVITY
air is pushed out
IE : RESULT
decrease in pressure in THORATIC CAVITY
MORE air is brought in
EE : RESULT
increase in pressure in THORATIC CAVITY
air is FORCED OUT
What is PARTIAL PRESSURE ?
concentration of gas in a space
What is DIFFUSION GRADIENT ?
gas moves from high pp to low pp
What is DIFFUSION ?
movement of particles across a partially permeable membrane (1 cell thick) down a diffusion gradient
What are the 2 “features” in the EXTERNAL SITE ?
alveoli and capillary
What are the 2 “features” in the INTERNAL SITE ?
muscle fibre and capillary
How many oxygen can haemoblobin hold ?
4
What is the product of oxygen and haemoglobin ?
oxyhaemoglobin
Where is there a high PP of O2 at the external site ?
in the alveoli / lungs
Where is there a high PP of CO2 at the external site ?
in the capillary
Where is there a low PP of O2 at the external site ?
in the capillary
Where is there a low PP of CO2 at the external site ?
in the alveoli / lungs
What is a partially permeable membrane ?
a membrane that is one cell thick
After the external site, where does the blood go ?
LA / LV / AORTA / MUSCLE
How many oxygen disassociate from the haemoglobin at the internal site ?
2
How many CO2 diffuse out of the muscle fibre ?
an equal amount - PP should always be equal
Where is there a high PP of 02 at the internal site ?
in the capillary
Where is there a high PP of CO2 at the internal site ?
in the muscle fibre
Where is there a low PP of O2 at the internal site ?
in the muscle fibre
Where is there a low PP of CO2 at the internal site ?
in the capillary
Does the capillary only contain O2 ?
no it carries some CO2
HEART RATE : REST : UNTRAINED
avg?
60 - 80
-avg=72bpm
HEART RATE : REST : TRAINED
and define bradycardia
> 60
reduction of resting heart rate to below 60bpm
HEART RATE : MAX
220 - age
STROKE VOLUME : REST : UNTRAINED
75 ml
What 3 factors is stroke volume determined by?
- venous return
- elasticity of cardiac fibres
- contractility of cardiac tissue
STROKE VOLUME : REST : TRAINED
up to 120ml
CARDIAC OUTPUT can reach
20-40l/min
BREATHING FREQUENCY : REST : UNTRAINED
12 - 15 breaths per min
BREATHING FREQUENCY : REST : TRAINED
11 - 12 breaths per min
BREATHING FRQUENCY : MAX : UNTRAINED
40 - 50 breaths per min
BREATHING FREQUENCY : MAX : TRAINED
50 - 60 breaths per min
TIDAL VOLUME : REST : UNTRAINED
0.5 l
TIDAL VOLUME : REST : TRAINED
0.5 l
TIDAL VOLUME : MAX : UNTRAINED
2.5 - 3 l
TIDAL VOLUME : MAX : TRAINED
3 - 3.5 l
MINUTE VENTILATION : REST : UNTRAINED
6 - 7.5 l/min
MINUTE VENTILATION : REST : TRAINED
5.5 - 6 l/min
MINUTE VENTILATION : MAX : UNTRAINED
100 - 150 l/min
MINUTE VENTILATION : MAX : TRAINED
160 - 210 l/min
Describe the structure of arteries/arterioles
- Thick elastic walls
- Small lumen
- Smooth muscle layer
Describe the structure of arteries/arterioles
- Thick elastic walls
- Small lumen
- Smooth muscle layer
Describe the function of arteries/arterioles
- Carry blood away from the heart
- Essential to the redistribution of blood