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Haematology > Pancytopenia > Flashcards

Pancytopenia Flashcards

1
Q

Name 2 drugs can cause bone marrow failure?

A

Chloramphenicol

Chemotherapy drugs

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2
Q

What vitamin deficiencies can cause pancytopenia?

A

B12/folate deficiency

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3
Q

What virus can cause bone marrow failure?

A

HIV

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4
Q

List 5 causes of hypersplenism?

A

Portal hypertension
Congestive cardiac failure
Rheumatoid arthritis
Myelofibrosis

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5
Q

Name an inherited cause of bone marrow failure syndrome?

A

Fanconi’s anaemia

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6
Q

What are the symptoms of anaemia?

A

Fatigue
SOB
Cardiovascular compromise

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7
Q

What are the symptoms of neutropenia?

A

Recurrent infections

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8
Q

What are the symptoms of thrombocytopenia?

A

Purpura

Petechiae

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9
Q

Will the marrow be hypocellular or hypercellular in aplastic anaemia?

A

Hypocellular

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10
Q

Will the marrow be hypocellular or hypercellular in myelodysplatic syndrome?

A

Hypercellual

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11
Q

Will the marrow be hypocellular or hypercellular in B12/folate deficiency?

A

Hypercellular. Problem with maturation

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12
Q

Will the marrow be hypocellular or hypercellular in hypersplenism?

A

Hypercellular

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13
Q

What are the options for supportive treatment in pancytopenia?

A

Red cell Transfusion
Platelet transfusion
Antibiotic prophylaxis (antibacterial) also antifungals and antivirals

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14
Q

How do you treat aplastic anaemia?

A

Immunosuppressive drugs

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15
Q

How do you treat congenital bone marrow failure?

A

Bone marrow transplant

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16
Q

How would you treat pancytopenia caused by HIV?

A

HAART to treat HIV which will correct the pancytopenia

Haematology (21 decks)

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