pancreatin insufficiency

Question 1

what is it

Answer 1

reduced exocrine secretion of pancreatic leads to malnutrition maldigestion and gi symptoms

Question 2

who it effects

Answer 2

CF, coelic , Zollinger Ellison, chronic pancreatitis, pancreatic/ gi resection pancreatic tumours

Question 3

advice

Answer 3

1)avoid reduced fat diets
2) avoid alcohol
3) avoid hard to digests foods i.e. legumes (peas, beans, and lentils, high fibre diet
4) have 3 main meals with fibre across all these and 2-3 snacks

Question 4

treatment

Answer 4

pancreatic (creon 3500)
- pancreatin supplement help with digestion starch , fat protein

Question 5

age for pancreatin

Answer 5

c/I for <15 with CF CAUSE strictures

Question 6

how take pancreatin

Answer 6

take with meals/snacks as it gets inactivated by gastric acid, can take immediately before or after

• if symptoms despite high pancreatic dose, add PPI acid suppressor

Question 7

s/e

Answer 7

1) GI effects common
2) fibrosing colonopathy in high dose pancreatin risks; male, more severe cf, laxative use
3)irritate; perioral skin, buccal mucosa
excessive use: hyperuricaemia, hyperuricosuria, perianal irritate

Question 8

counsel

Answer 8

drink plenty water with high strength prep al times exa nutrizym pancreas HL