Pancreas Flashcards
Initial 48 hrs in acute pancreatitis
CHOBBS Ca 10% O2 5 Base deficit >4 Sequestration >6L
Ransons criteria
GALAW Glucose >200 AST >250 LDH >350 WBC >16000
Most appropriate treatment for acute pancreatitis
Bowel rest NPO
Most appropriate analgesic for patient with acute pancreatitis
Meperidine ( does not cause dysfunction of sphincter of oddi)
Mcc of chronic pancreatitis
Long term alcohol abuse
Strongest environmental influence in Pancreatic adeno ca
Cigarette smoking
Mc location of pancreati adeno ca
Head
True or false
Carcinoma of the body and tail of the pancreas do not impinge on the billiary tract
True
Painless obstructive jaundice
Trosseau sign
Pancreatic carcinoma
Tumor marker for pancreatic ca
CA 19-9
Surgical tx for pancreatic ca
Whipples procedure (pancreaticoduodenectomy)
Can be mistaken for pancreatic ca
Mirrizi syndrome
2 main vascular cells
Endothelial- intima
Smooth muscle - media
Weibel palade bodies
Endothelial cells
TRUE aneurysm
Syphilitic
Atherosclerotic
Congenital aneurysm
Aortic dissection vs false aneurysm
Aortic dissection- blood in single vessel layer
False aneurysm- blood in two vessel layer
Defect at the junction of the communicating branches with the main cerebral vessels (ant communicating artery)
Sudden occipital HA
Berry aneurysm
Asso.w/ tertiary syphilis
Invasion of vasa vasorum of thoracic aorta (obliterative endarteritis)
Aortic valve regurgitation
Syphilitic aneurysm
Invasion of vasa vasorumā> hypoxia and death of tunica media ā> aorta loss elastic recoilā> syphilitic
Dissection of blood between laminar parts of tunica MEDIA
Aortic dissection/dissecting hematoma
Type A and type B in aortic dissection/ dissecting hematoma
Type A - proximal ( ascending or both ascending an d descending)ā> surgery
Type B - distal (begins at distal subclavian artery)
Most frequent pre existing histologic lesion in aortic dissection
Cystic medial degeneration/ necrosis
Mc locations of varicose veins
Superficial saphenous veins
Distal esophagus
Anorectal regions
Left scrotal sac
Varicose vein does not lead to thromboembolism
True
Important clinical finding in aortic dissection
Loss of UPPER extremity pulses
Mc location of phlebothrombosis
Calf deep vein
Vein thrombosis without inflammation
Caused by blood stasis or hypercoagulability
Phlebothrombosis
Orange discoloration and ischemic ulcers around ankles
Phlebothrombosis
Puffiness, cyanosis of head, neck, arm veins
Asso.with Primary lung Ca or mediastinal lymphoma
SVC syndrome
Compression of the neurovascular components of the neck
Spastic anterior scalene muscles
Thoracic outlet syndrome
Hardening of the arteries
Arteriosclerosis
2 types of arteriosclerosis
Hyaline variant ā major charac. Of benign nephrosclerosis
Hyperplastic variant ā (+) concentric hypertrophy
Mc site of atherosclerosis
Abdminal aorta
Complication of atherosclerosis
Superimposed thrombosis
MI, stroke, Small bowel infarction
Criteria for hypertensive heart disease
LVH in absence of cardiac pathology
Earliest manifestation of hypertensive heart disease
Inc.in the transverse diameter of myocytes
P-ANCA
Churg strauss syndrome, microscopic polyangitis
Ab against myeloperoxidase (MPO)
C-ANCA
Wegener granulomatosis
Ab against proteinase 3
Mc form of systemic vasculitis in adults
Temporal (giant cell) arteritis
Artery involve in temporal giant cell arteritis
Temporal artery
Opthalmic artery
Pulseless disease
Takayasu arteritis
Segmental transmural necrotizing inflammation of small to medium sized arteries
More of renal artery
Does not affect the pulmonary arteries
PAN
Young adult
Positive HBsAg
Fatal ā RF but no GN
PAN
Mc acquired heart dsea in children
Coronary artery most often affected
Kawasaki
Treatment of KAWASAKI
ASA, IVIg
Only indication for ASA in children
RF
Kawasaki
Juvenile RA
Allergic granulomatosisa and angitis
Churg strauss syndrome
Triad of Wegener granulomatosis
Necrotizing granuloma
Necrotizing vasculitis
Necrotizing glomerulitis
Cās of wegener
C anca
Cyclophosphamide
Corticosteroid
Cresentricn GN
Resting pain of forefoot
Thromboangitis Obliterans
Normal weight of heart
300-350g (50g less in females)
Inc. BNP
Left sided S3
Inc.BNP
Bat wing configuration
Left sided heart failure
Causes of high output heart failure
Beri beri
Anemia
Hyperthyroidism
AV fistula
Mc congenital disease
VSD, followed by asd, ps, pda, tof
Mc genetic risk for chd
Down syndrome
L to R shunt
Acyanotic
Asd, vsd, pda avsd
Mc cyanotic congenital heart dsea.
TOF
Component of TOF
Pulmonic stenosis
RVH
Overriding of VSD by the aorta
VSD
Tet spells, do squatting
TOF
Boot shaped heart
TOF
Egg shaped cardiac silhouette
Transposition of great vessels
Mc adult chd
ASD
Mc type of ASD?
Secundum
Chd with fixed widely split S2
ASD
Mc CHD
VSD
Chd asso.with congenital rubella
PDA
Machinery murmur
Pda
Death within one hour
Occurs early morning
CAD-90%
Sudden cardiac death
Romano ward syndrome (AD long QT syndrome)
Brugada syndrome
Sudden cardiac death
ST elevation, Q waves
Full thickness, transmural
Early mortality rate
Q wave infarction MI
Partial thickness/subendocardial
ST depression
Inc risk for SCD
Non Q wave MI
Coagulation necrosis in M.I happens at what hour
4-12 hrs
Wavy fibers and myoctolysis
Reperfusion in M.I
6 hrs ā no appreciable reduction in M.I size
Opening snap
Mitral stenosis
Midsystolic click
Mitral valve prolapse
Austin flint murmur
Aortic regurgitation
Graham steel murmur
Pulmo regurgitation