pales, anemia, DSA Flashcards
Causes of microcytic anemia
Fe deficiency
anemia of chronic disease
thalassemia
lead toxicity
cuases of macrocytic anemia
B12 def
folate def
alcoholic liver disease
MDS
causes of normocytic anemia
hemolytic aplastic hypersplenism mixed hemodilution anemia of chronic disease anemia of uremia acute bleeding
ddx for microcytic hypochromic anema
Fe def
lead poisoning
anemia of inflammation
thalassemia
what is TIBC
total iron binding capacity
how many iron binding sites are available (extra binding than already bound)
low ferritin is pathoneumonic of what
Fe deficiency
does normal or high ferritin rule out Fe deficiency
no because it is an acute phase reactant
buzzword thalassemia based on where you are from
arab american
what are RBC and MCV levels in thalassemia
high RBc
low MCV
confirm thalassemia?
Hb electrophoresis and genotypic analysis
how do you know if Fe supplementation is helping with Fe def anemia 1 week later?
reticulocyte count should be increased from before Tx started
what type of def can be caused by gastric bypass
B12 def
quickest way to replace Fe
blood transfusion
RDW goes up when what
more than 2 populations of different size RBC
how do you Dx anemia of chronic disease
elevated or normal ferritin
low TIBC!!!! and Fe