pales, anemia, DSA Flashcards

1
Q

Causes of microcytic anemia

A

Fe deficiency
anemia of chronic disease
thalassemia
lead toxicity

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2
Q

cuases of macrocytic anemia

A

B12 def
folate def
alcoholic liver disease
MDS

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3
Q

causes of normocytic anemia

A
hemolytic
aplastic
hypersplenism
mixed
hemodilution
anemia of chronic disease
anemia of uremia
acute bleeding
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4
Q

ddx for microcytic hypochromic anema

A

Fe def
lead poisoning
anemia of inflammation
thalassemia

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5
Q

what is TIBC

A

total iron binding capacity

how many iron binding sites are available (extra binding than already bound)

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6
Q

low ferritin is pathoneumonic of what

A

Fe deficiency

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7
Q

does normal or high ferritin rule out Fe deficiency

A

no because it is an acute phase reactant

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8
Q

buzzword thalassemia based on where you are from

A

arab american

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9
Q

what are RBC and MCV levels in thalassemia

A

high RBc

low MCV

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10
Q

confirm thalassemia?

A

Hb electrophoresis and genotypic analysis

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11
Q

how do you know if Fe supplementation is helping with Fe def anemia 1 week later?

A

reticulocyte count should be increased from before Tx started

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12
Q

what type of def can be caused by gastric bypass

A

B12 def

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13
Q

quickest way to replace Fe

A

blood transfusion

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14
Q

RDW goes up when what

A

more than 2 populations of different size RBC

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15
Q

how do you Dx anemia of chronic disease

A

elevated or normal ferritin

low TIBC!!!! and Fe

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16
Q

how do you check for hemolytic anemia

A

haptoglobin! (dec if hemolytic anemia)
LDH
unconjugate bilirubin