pales, anemia, DSA

Question 1

Causes of microcytic anemia

Answer 1

Fe deficiency
anemia of chronic disease
thalassemia
lead toxicity

Question 2

cuases of macrocytic anemia

Answer 2

B12 def
folate def
alcoholic liver disease
MDS

Question 3

causes of normocytic anemia

Answer 3

hemolytic
aplastic
hypersplenism
mixed
hemodilution
anemia of chronic disease
anemia of uremia
acute bleeding

Question 4

ddx for microcytic hypochromic anema

Answer 4

Fe def
lead poisoning
anemia of inflammation
thalassemia

Question 5

what is TIBC

Answer 5

total iron binding capacity

how many iron binding sites are available (extra binding than already bound)

Question 6

low ferritin is pathoneumonic of what

Answer 6

Fe deficiency

Question 7

does normal or high ferritin rule out Fe deficiency

Answer 7

no because it is an acute phase reactant

Question 8

buzzword thalassemia based on where you are from

Answer 8

arab american

Question 9

what are RBC and MCV levels in thalassemia

Answer 9

high RBc

low MCV

Question 10

confirm thalassemia?

Answer 10

Hb electrophoresis and genotypic analysis

Question 11

how do you know if Fe supplementation is helping with Fe def anemia 1 week later?

Answer 11

reticulocyte count should be increased from before Tx started

Question 12

what type of def can be caused by gastric bypass

Answer 12

B12 def

Question 13

quickest way to replace Fe

Answer 13

blood transfusion

Question 14

RDW goes up when what

Answer 14

more than 2 populations of different size RBC

Question 15

how do you Dx anemia of chronic disease

Answer 15

elevated or normal ferritin

low TIBC!!!! and Fe

Question 16

how do you check for hemolytic anemia

Answer 16

haptoglobin! (dec if hemolytic anemia)
LDH
unconjugate bilirubin