Pain Flashcards
Physiological process of pain
transduction
transmission
perception
modulation
Nociceptors
sensory neurons that detect painful stimuli
Chemical Mediators causing pain
prostaglandins (tissue cell membrane) histamine (mast cells) bradykinin (liver protein) serotonin (platelets) substance P
Epidemiology of pain in OA
> 50% in community have chronic pain
>80% in nursing homes have chronic pain
Acute Pain
rapid onset
clearly linked to triggering injury/event
short duration
decreases with healing
Chronic Pain
pain lasting >3 months. can last years
can be d/t underlying pathology, injury, medical treatment, inflammation, neuropathic
Pain Theories
gate-control theory
neuromatrix theory
Eudynic pain
normal transduction of pain sensation d/t noxious stimuli
Types of pain
referred
cutaneous
somatic
visceral
Somatic pain
sharp pain localized to an area of injury
Visceral pain
pain that occurs w/i a body cavity (thorax, abdomen, pelvis)
may radiate to other area
caused by: swelling, stretching, hypoxia
Hypoxia
pain caused by decreased availability of oxygen to tissue cells
can occur d/t hypoperfusion or hypoxemia
Nociceptive pain
eudynic pain
normal associated with tissue injury
Neuropathic pain
caused by disease or pathology to the somatosensory system
pain sensation that originates in the PNS/CNS without afferent stimuli
Neuropathic pain exemplars
postherpetic neuralgia diabetic neuropathy phantom pain trigeminal neuralgia post-stroke pain complex regional pain syndrome
Individual Risk Factors
communication barriers
cognitive impairment or developmental barriers
Pain assessment tools
pain scale (numbers or faces)
self-assessment
behavioral pain tools
Analgesic classes
non-opioid
opioid
adjuvant analgesic
Non-Opioid analgesia
acteminophen
NSID
COX-2 selective NSAID
*mild pain. used as an adjunct w/ opioids
Opioid analgesia
hydromorphone oxycodone fentanyl morphine *moderate-severe pain
Adjuvant analgesai
anticonvulsant (gabapentin)
local anesthesia
antidepressant
First Line Treatment for Neuropathic Pain
anticonvulsants (gabapentin)
antidepressants
Somatic Senses
pain
touch
temperature
proprioception
Types of somatic neurons
general - pain, touch, temp. widespread
special somatic - muscles, joints, tendons. proprioception & kinesthesia
general viscera - viscera. fullness & discomfort
Somatosensory pathway
1st order neuron - periphery to CNS
2nd order neuron - reflex/sensory pathway. spinal cord –> thalamus
3rd order neuron - thalamus –> cerebral cortex
Types of somatosensory fibers (peripheral)
A, B, C