Paediatric Dermatology Flashcards
What is eczema?
Itchy, dry inflammatory skin disease
What is the normal gene expression in eczema?
Abnormality in filaggrin expression
What is the function of filaggrin?
Proteins bind keratin filaments together and help maintain moisture
What is the distribution of eczema?
Flexural in older children
Face, neck, hands in infants
Discoid, generalised
What can eczema flares be associated with?
Infections/ viral illness Central heating, cold air Pets Teething Stress
What is seborrheoic dermatitis also known as?
Cradle cap
Where is seborrheoic dermatitis found?
Scalp and face
Flexures- neck, wirst, hands
What is the treatment for seborrheoic dermatitis?
Emollients
Antifungal cream and shampoo
Mild topical steroids
What does discoid eczema look like?
Scattered annular/circular patches
What are the features of pompholyx eczema?
Hand and foot eczema
Vesicles, bullae
Intensely itchy
What is the treatment for pompholyx eczema?
High potency steroid
What type of reaction is allergic eczema?
Type 4 hypersensitivity
How can allergic eczema be tested for?
Patch testing
What can cause irritant eczema?
Water, saliva
Soaps, bubble baths
Irritant foods (citrus, tomatoes)
Chemical irritants
When should a food allergy be suspected?
Angioedema, facial rash Worsening of eczema 24/48 hours after ingestion GI symptoms (vomiting) Failure to thrive Severe eczema unresponsive to treatment Severe generalised itching