Oxygenation Flashcards
Important Concepts
Oxygenation
Respiration
Ventilation
Respirations and ventilations oxygenate the blood
Oxygenation of the blood, and subsequently organs and tissues depends on an adequate ventilation
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Is the exchange of gases oxygen and carbon dioxide in the lungs
Respiration
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Is the movement of air in and out of the lungs through the act of breathing
Ventilation
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Refers to how well the cells in tissues and organs of the body are supplied with oxygen
Oxygenation
Anatomy
Airway
- Moisten
- Warm
- Filter
- Cilia
Upper Airway
- Pharynx
- Trachea
- Epiglottis
Lower Airway
- Trachea
- R&L Bronchi
- Bronchioles
Airway
In addition to allowing air to flow in and out of the lungs, the airway also moistens air - moist mucous membranes add water to the inhaled air
Warms air (body heat is transferred to passageways through blood flow), and filters air - cells secrete sticky mucous whose action is to filter foreign particles
___ - tiny, hair-like projections on the airway walls, that move like a sweeping motion and pick up trapped debris up and out of the airway
Cilia
Upper airway
Nasal passageways
Mouth
Pharynx (throat)
Trachea
___ (flap of tissue that closes off trachea during swallowing to prevent food from entering the trachea and opens during breathing to allow air into lungs)
Epiglottis
Lower airway (STERILE)
Trachea
Bronchi
Bronchioles
Walls of bronchi and bronchioles have ____ which can narrow the airway and obstruct blood flow with ___
layers of smooth muscles
bronchospasm
Lungs
- Are soft, spongy cone-shaped organs separated by the mediastinum
- The right lung has ___ lobes and the left lung has ___ lobes
- The ___ is the upper portion of the lung, usually extends upward above the clavicle
- The base of the lungs is the lower portion of the lungs that rests on the diaphragm
- ___ are tiny little air sacs with thin walls surrounded by a network of capillaries where gas exchange occurs
3; 2
apex
alveoli
Pulmonary System Functions - Pulmonary Ventilation
Ventilation is achieved through cycles of ___ and ___
___ is the expansion of the chest cavity and lungs creating negative pressure inside the lungs causing air to be drawn in through the nose or mouth and airways
___ occurs when the diaphragm and intercostal muscles relax allowing the chest and lungs to return to their normal resting size
inhalation; exhalation
Inhalation
Exhalation
The ___ is the major muscle of breathing
The ___ are small muscles around the ribs
The ___ covers the lungs and lung expansion creates a negative pressure to draw in air
diaphragm
intercostal muscles
pleural membrane

Respiratory rate is how fast you breathe
Respiratory depth is how much your lungs expand to allow room for air
___ occurs with a decreased rate or shallow breathing and it moves only small amounts of air into in and out of the lungs leading to ___ less oxygenated air reaches the alveoli
Hypoventilation
hypoxemia
___ occurs when a person breathes too fast so large amounts of air entered into the lungs causing too much carbon dioxide to be removed from the alveoli
Lung elasticity or lung recoil is the ability of elastic fibers to return to their original position; this allows the lung to inflate easily but inhibits deflation leaving air trapped in the alveoli - similar to the overstretching of an elastic band
Hyperventilation
Lung compliance is the ease of lung inflation - which should inflate easily
Airway resistance is the resistance to air flow within the airways - the larger the diameter of the airflow the easier the air moves through it
Respiration (Gas Exchange)
External - At the level of the ___ (alveoli)
Internal - At the level of the ___ and ___
lungs
tissues & organs
External respiration or alveolar-capillary gas exchange occurs in the alveoli of the lungs
Where oxygen diffuses across the capillary membrane into the blood of the pulmonary capillaries and carbon dioxide diffuses out of the blood and into the alveoli to be exhaled
Rate of diffusion is going to depend on the thickness of the membrane and the total surface of the lung tissue available for that lung exchange
* Conditions that slow diffusion include pleural effusion, pneumothorax, and asthma
If blood is not adequately oxygenated in the alveoli - hypoxemia (low blood oxygen levels) may occur
Internal respirations or capillary-tissue gas exchange occurs in body organs and tissues
So, oxygen diffuses from the blood through the capillary-cellular membrane into the cells where it’s used for metabolism and carbon dioxide (which is a waste product of cellular metabolism) diffuses from the cells through the capillary-cellular membrane into the blood and then it’s transported to the lungs where it’s going to be exhaled

What controls breathing?
Chemoreceptors
* Detect changes in pH, O2, & CO2 (increase or decrease in ventilation)
Lung receptors
* Sensitive to breathing patterns, lung expansion, lung compliance, airway resistance, and respiratory irritants
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Located in the middle of the brainstem, the carotid arteries, and aorta
Detect changes in blood pH, O2, and CO2 levels and send messages to the central respiratory system in the brainstem in response the respiratory system increases or decreases in ventilation to maintain normal blood levels of pH, pO2 and pCO2
Chemoreceptors
High levels of carbon dioxide stimulate breathing to eliminate that excess carbon dioxide - very important to know that blood carbon dioxide levels provide the primary stimulus to breathe; PRIMARY DRIVE TO BREATHE
Low blood oxygen levels stimulate breathing to get more oxygen into the lungs, so hypoxemia is a SECONDARY DRIVE TO BREATHE
___ - PRIMARY DRIVE TO BREATHE
___ - SECONDARY DRIVE TO BREATHE
CO2 blood levels
Hypoxemia
Lung receptors
Are located in the __ and ___
Are sensitive to breathing patterns, lung expansion, lung compliance, airway resistance, and respiratory irritants
For example, if lung receptors sense respiratory irritants like dust, cold, air, or tobacco smoke - that will trigger respiratory centers to constrict the airway and produce a more rapid, shallow pattern of breathing
lung & chest wall
External Factors Influencing Pulmonary Function
- Developmental stage
Changes in pulmonary A&P place OLDER ADULT at HIGHER RISK for RESPIRATORY INFECTIONS
- ↓ lung expansion and less alveolar inflation (d/t costal cartilage calcifications and reduction in chest wall movement during breathing)
- Loss of recoil and alveoli elasticity
- Drier mucus membranes and less cilia
External Factors Influencing Pulmonary Function cont’d
- Exhalation less efficient
- Decline in immune response
- GERD more common (leading to risk for aspiration)
- Slow chemoreceptor response (makes hypoxemia more likely)
All of these changes place the older adult at risk for respiratory infections




















