Fluids, Electrolytes, & Intravenous Therapies Flashcards
Composition of Body Fluid
Water
Gases
Solutes
* Electrolytes
* Nonelectrolytes
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These develop an electrical charge when dissolved in water
e.g. Na+, K+
electrolytes
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These do not conduct electricity within water
e.g. glucose
Nonelectrolytes
The total amount of body fluid varies and is based on age, sex, and amount of adipose tissue present
Function of Body Fluids
- Maintain blood volume
- Regulate body temperature (sweating)
- Transport material to and from cells
Function of Body Fluids cont’d
- Serve as medium for cellular metabolism
- Assist with digestion of food
- Serve as a medium for excreting waste
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Is body fluid that is contained within the cells
Contains ___ (potassium, magnesium) and ___ (phosphate)
Intracellular fluid
cations, anions
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Is body fluid that is found outside of the cells
Contains sodium, chloride, bicarbonate, albumin, transcellular fluids
Extracellular fluid
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Plasma in the blood; main function is to transport blood cells
Intravascular fluid
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Lies in spaces between body cells
edema - is excess fluid within this ___ space
Interstitial fluids
interstitial
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Specialized fluids contained within body spaces
e.g. CSF, peritoneal fluid, digestive secretions
Transcellular fluid
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Occurs where fluid is trapped in another compartment, not within interstitial cells or within the intravascular space
Due to low albumin levels, hypervolemia (fluid overload), decreased sodium levels
Creates a sort of generalized edema; seen in the legs, thighs, abdomen, and face
Third spacing
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Occurs when molecules move across a cellular membrane against a concentration gradient
Requires energy expenditure
Vital for maintaining the composition of both the extracellular and intracellular compartments
Active transport
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In the presence of ATP, actively moves ___ from the cell into the extracellular fluid and ___ from the extracellular fluid into the cell
Sodium-Potassium Pump
sodium; potassium
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Releases from the cell to enable substances to acquire the energy needed to pass through the cell membrane
Adenosine Triphosphate (ATP)
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Is a type of passive transport
Movement of water or other pure solute across a membrane from an area of a less concentrated solution to an area of a more concentrated solution
Solutes can be crystalloids or colloids
Osmosis
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A form of passive transport
Process where solute molecules move through a cell membrane from an area of higher concentration to an area of lower concentration
Movement occurs until the concentrations are equivalent on both sides of the membrane
Diffusion
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Is another type of passive transport
Filtration
What is a major regulator of fluid intake?
Fluids should be non-caffeinated; no sugar added
Thirst
Fluid Intake
Recommended Daily Intake
Men: ___ mL/day
Women: ___ mL/day
Older Adults: ___ to ___ mL/day
3,700
2,700
1,500 - 2,000
Thirst
Increased by excessive fluid loss, excessive sodium intake, and decreased fluid intake
Thirst cont’d
Decreased by high fluid intake, fluid retention, excessive intravenous infusions, and low sodium intake
Fluid Output
Common Sources of Fluid Loss
Urine: ~150 mL/day
Feces: ~100-200 mL/day
Skin: ~600 mL/day
Lungs: ~300 mL/day
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Is fluid loss that we do not easily perceive, not easily measured
e.g. perspiration/sweating/breathing
Insensible Fluid Loss
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Is fluid loss that is measurable and perceived
e.g. urine, diarrhea, ostomy/gastric drainage
Sensible Fluid Loss
Hormones Affecting Fluid Regulation
Antidiuretic Hormone
Renin-Angiotensin System
Aldosterone
Thyroid Hormone
Brain Natriuretic Peptide (BNP)
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Causes the kidneys to retain fluid; based on fluid pressures in the vascular system
Triggered by fever, pain, stressor in response to opioids
Antidiuretic Hormone
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Occurs in response to decreased ECF volume
Glomeruli in kidneys release ___ which converts ___ to ___ which then acts on nephrons to retain Na+ and H2O
Directs adrenal cortex to release aldosterone
Renin-Angiotension System
renin
angiotension
angiotension II
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Stimulates distal tubules of kidneys to reabsorb Na+ and excrete K+; causes a passive reabsorption of H2O
Aldosterone
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Can influence/increase cardiac output which in turn increases glomerular filtration rate and urine output
Thyroid Hormone