Oxygen Transport and Oxyhgb Curve

Question 1

What determines the characteristics of the oxyhemoglobin

(Hbo2) dissociation curve?

Answer 1

The affinity of Hb for O2

Question 2

What is considered having the greatest impact on the affinity of Hb for O2.

Answer 2

pH
temperature
concentration of 2,3-diphosphoglycerate (2,3-DPG)

Question 3

Five variables affect O2 delivery:

Answer 3

(1) Hb concentration
(2) Hb affinity for O2 (P50)
(3) percent O2 saturation of Hb (Sao2)
(4) CO
(5) the amount of O2 dissolved in blood (usually not meaningful amounts).

Question 4

The arterial O2 content (Cao2) is calculated as the:
Ca O2 (Hb 1.39 SaO2 /100) (PaO2 0.0 03)
For example, if Hb is 15 g/dL, Sao2 is 100%, and Pao2 is 100 mm Hg

Answer 4

sum of the O2 bound by Hb and the O2 dissolved in the plasma

Question 5

CaO2 formula is

Answer 5

CaO2 = (Hb x 1.39 x SaO2/100) + (PaO2 x 0.003)

Question 6

Oxygen delivery (DO2) to the tissues is the product of

Answer 6

CO and Cao2.