Oxidation of Pyruvate Flashcards
1
Q
What is the reducing agent in the oxidation process?
A
NAD
2
Q
Where does the oxidation occurs?
A
Mitochondrial Matrix
3
Q
What is the function of the oxidation of pyruvate?
A
It is the preparatory step for the TCA, and forming Acetyl CoA
4
Q
What are the cofactors in the pyruvate dehydrogenase complex?
A
Coenzyme A (CoA) Thiamine pyrophosphate (TPP) NAD+ FAD+ Lipoic Acid
5
Q
Where are these cofactors found in our food supply?
A
.
6
Q
Beriberi is due to deficiency of?
A
Thiamine
7
Q
Pellegra is due to a deficiency of?
A
Niacin
8
Q
The reaction is regulated negatively by?
A
Acetyl CoA and NADH
9
Q
The reaction is regulated positively by?
A
ADP and CA+
