Lipolysis and B-oxidation Flashcards
The complete hydrolysis of triacylglycerol yields?
glycerol & 3 fatty acids
What can glycerol be used for?
Energy for glycolysis and to form glucose via gluconeogenesis
How do fatty acids cross the inner mitochondrial membrane?
Via transporter, canitine
What do CAT I and Cat II do?
Bring fatty acid into the mitochondrion
What is the difference in the B-oxidation of saturated vs unsaturated fatty acids?
In unsaturated fatty acid beta oxidation we already have a double bond that occurs naturally, therefore we surpass step number one, resulting in two less ATP
Is there a difference in calories production from sat vs. unsat fat?
Unsaturated fat has slightly fewer calories than saturated fatty acids.
What is the fate of most of the end product of B-oxidation (in the non-starved state)?
acetyl coa going into the krebs cycle
In odd-numbered carbon fatty acid chains, the end of B-oxidation results in what compound?
propionyl coA (3 carbons) > with help of biotin and b12 > succinyl CoA > krebs cycle
Why are fatty acids a richer source of energy than CHO?
Because Fatty Acids are in a more reduced form than CHO, therefore undergo a greater amount of oxidation on the way to CO2 and H20, yielding more ATP
Why do fats have more cal per gram?
because fats are in more reduced state because of more Hydrogen, so more ATP is produced. More ATP more calls
where does oxidation of fatty acids occur?
mitochondrion
Palmitoyl CoA gives of 2 hydrogens from beta carbon and alpha carbon creating
unsaturated 16 c
