Oxford Clinicals II

Question 1

SLE can be triggered by which virus?

Answer 1

EBV

Question 2

Are females or males more prone to SLE?

Answer 2

Females, typically women of childbearing age

Question 3

Typical patient: A man <30 years old with gradual onset of low back pain, worse at night, with spinal morning stiffness relieved by exercise.
What condition is this?

Answer 3

Ankylosing Spondylitis

Question 4

What is enthesitis?

Give examples of enthesitis.

Answer 4

Enthesitis is inflammation of the site of insertion of tendon or ligament into bone.
Examples include plantar fasciitis, Achilles tendonitis, costochondritis.

Question 5

Which are the 5 conditions that are HLA-B27 positive?

Answer 5

Ankylosing Spondylitis (88% of patients - highest)
Acute anterior uveitis
Reactive arthritis
Enteric arthropathy
Psoriatic arthritis

Question 6

Why will there be decreased thoracic expansion with ankylosing spondylitis?

Answer 6

This is due to progressive loss of spinal movemnet

Question 7

What is the posture characteristic of Ankylosing Spondylitis?

Answer 7

Question-mark posture (hyperextension of neck and kyphosis)

Question 8

What is enteric arthropathy associated with?

After the treatment of -blank-, arthropathy often improves.

Answer 8

Enteric Arthropathy is associated with inflammatory bowel disease, GI bypass, coeliac and Whipple’s disease.
Arthropathy often improves with treatment of bowel symptoms.