Overview of the immune system Flashcards
What four major categories do pathogens fall into?
- Viruses
- Bacteria
- Fungi
- Parasites
what is pathogenesis?
the process by which they induce disease
What are the goals of the immune system?
- Prevent entry of pathogen
- Prevent growth of pathogen
- Kill the pathogen
- Eliminate pathogen and repair damage
- Kill the pathogen and don’t kill the host
What are the functions of the immune response?
- Recognition (self vs non-self)
- Effector function (respond)
- Regulation (control degree)
- Memory (recurrent infection)
How is disease calculated?
What are the two immunities mammals have?
Innate immunity
Adaptive Immunity
Compare Innate vs Adaptive immunity
1. Response time
2. Specificity
3. Response to repeat infection
4. Major Components
When does the innate and the adaptive immunity kick in?
What does the innate immune system use to develop their recognition molecules?
Use germ-line-encoded recognition molecules
What does the adaptive immune system use to develop their recognition molecules?
Humoral and cell-mediated immunity relies on surface receptors, how are these created?
What are the components of the immune system (nonspecific/specific)
How does the innate and adaptive immunity work cooperatively?
What is clonal selection and how does it generate diversity?
- When a B or T cell interacts with its specific antigen, it is selected and becomes activated
- Activation results in a proliferation, producing a large number of clones
- each clone is reactive against the antigen that initially stimulated the original lymphocyte
In what branch of the immune system does memory come into play and how does it work?
What is the function of the microbiome?
What are the two broad categories of a dysfunctional immunity?
