Allergies Flashcards
What are hypersensitive reactions are examples of this reaction type?
Inappropriate or heightened inflammatory response
Initiated during the course of either humoral or cell-mediated response and can cause tissue damage or death
Ex. Hay fever 20%
Asthma ~ 5%
Who are Paul Portier and Charles Richet?
They are credited as the first to identify hypersensitive reactions.
They developed vaccinations to toxins of Jellyfish and the results of boosters in dogs.
They are credited for coining the term anaphylatoxins.
Hypersensitivity reaction overview and types
What are the types of hypersensitivity reactions?
What are the genetic effects on susceptibility to type I hypersensitivity?
Draw the Type I hypersensitivity reaction process.
What antibodies are responsible for type I hypersensitivity reactions?
IgE antibodies are responsible for type I hypersensitivity.
Allergies are initiated by an interaction between an IgE and antibody and a multivalent antigen
Free circulating IgE is usually very, very low in concentration in blood serum.
What allergens elicit Type I response
Common causes of type I reactions