Effector Response Flashcards by Santos Ramirez

Q

How are B cells activated and what do they differentiate into?

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Q

Explain Antibody-Mediated effector functions. What antibody isotopes mediate different effector functions?

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Q

What are the six effector functions of antibodies?

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Q

What are the different parts of an antibody?

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Q

Tell me about the hypervariable region, antibody combining site, complementarity-determining regions, and framework region?

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Q

Tell me about IgM

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Q

Tell me about IgG?

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Q

IgG1

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IgG2

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IgG3

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IgG4

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Q

Tell me about IgA?

Draw it?

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Q

How is IgA made secretory IgA?

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Q

Describe IgE

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Q

Describe IgD

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Q

What different body parts are IgG, monomeric IgA, dimeric IgA, and IgE located?

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Q

What are Fc receptors?

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Q

What is the most diverse group of FcRs?

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Q

What are FceR?

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Q

What are FcaR?

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Q

What are FcuR and FCA/uR

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Q

What is PolyIgR?

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Q

What is FcRn?

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Q

What are chimeric antibodies?

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Q

What are the three subsets of cytotoxic effector cells?

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Q

What are CTLs?

How are the generated?

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Q

How are APC licensed to create CTLs?

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Q

How do cytotoxic T lymphocytes recognize and kill infected or tumor cells?

What are the different types of CTL

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Q

What are the stages in CTL-mediate killing of target cells?

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Q

How do CTLs kill target cells? (2)

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Q

What do NK cells do?

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Q

What is the missing self model and the balanced signal model regarding NK cells?

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Q

How do NK cell mediate apoptosis?

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Q

How are NK cells licensed?

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Q

What’s up with NK cell memory?

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Q

How do NKT cell bridge innate/adaptive immune system?

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