Effector Response Flashcards by Santos Ramirez

Q

How are B cells activated and what do they differentiate into?

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Q

Explain Antibody-Mediated effector functions. What antibody isotopes mediate different effector functions?

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Q

What are the six effector functions of antibodies?

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Q

What are the different parts of an antibody?

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Q

Tell me about the hypervariable region, antibody combining site, complementarity-determining regions, and framework region?

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Q

Tell me about IgM

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Tell me about IgG?

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IgG1

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IgG2

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IgG3

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IgG4

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Q

Tell me about IgA?

Draw it?

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Q

How is IgA made secretory IgA?

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Q

Describe IgE

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Describe IgD

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Q

What different body parts are IgG, monomeric IgA, dimeric IgA, and IgE located?

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What are Fc receptors?

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What is the most diverse group of FcRs?

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What are FceR?

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What are FcaR?

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What are FcuR and FCA/uR

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What is PolyIgR?

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What is FcRn?

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What are chimeric antibodies?

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What are the three subsets of cytotoxic effector cells?

What are CTLs? How are the generated?

How are APC licensed to create CTLs?

How do cytotoxic T lymphocytes recognize and kill infected or tumor cells? What are the different types of CTL

What are the stages in CTL-mediate killing of target cells?

How do CTLs kill target cells? (2)

What do NK cells do?

What is the missing self model and the balanced signal model regarding NK cells?

How do NK cell mediate apoptosis?

How are NK cells licensed?

What's up with NK cell memory?

How do NKT cell bridge innate/adaptive immune system?