Overview of Risk Flashcards
What is “Risk”
likelihood an adverse event will occur
What is risk in public health terms
measure of the probability and severity of adverse health consequences
When is something “safe”
risks are judged to be acceptable
Risk assessment
tool to evaluate, organize, and quantify risk information
Risk management
process of converting risk assessment into public policy for purpose of protecting public health
Risk assessment steps
- Hazard Identification
- Dose response assessment
- Exposure Assessment
- Risk characterization
Hazard identification
is it a hazard?
Review toxicity data
check evidence that has toxic effect
Dose response assessment
What dose ranges does risk occur and how much risk
- assess relevance of studies
- extrapolate
Exposure Assessment
are people exposed and how
Risk characterization
How to explain the risk
develop framework
present assumptions and judgements
diol epoxide
reactive species (oxygen group) formed on benzene ring. like from cigarette smoke
most sensitve part of DNA to damage
double bond
Exposure is
contact with harmful something
Exposure is not
ambient level or dose
Ambient level
how much material is in environment
