Environmental carcinogenesis Flashcards
1
Q
NHEJ
A
Non-homologous end joining
2
Q
HRR
A
homologous recombination repair
3
Q
BER
A
Base excision repair
4
Q
NER
A
Nucleotide excision repair
5
Q
MMR
A
mismatch repair
6
Q
HNPCC
A
Human Non-polyposis Colon Cancer
causes colon cancer
7
Q
HNPCC type of damage
A
mismatch repair
8
Q
Ataxia telangiectasia
A
lymphomas and leukemias
9
Q
Bloom syndrome
A
leukemias, lymphomas, carcinomas
10
Q
Cockayne’s syndrome
A
no known cancer
11
Q
Trichothiodystrophy
A
no known cancer
12
Q
Werner syndrome
A
thyroid cancer, melanoma, sarcoma, osteosarcoma
13
Q
Xeroderma pigmentosum
A
skin cancer
sensitive to UV radiation
7 nucleotide excsion repair genes
14
Q
gorlin syndrome
A
BCC, meduloblastoma
sensitive to IR
PTCH gene
15
Q
pyrimidine dimer formed by
A
254 nm UV
