Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

IMMUNOLOGY AND SEROLOGY :) > OVERVIEW OF IMMUNE SYSTEM > Flashcards

OVERVIEW OF IMMUNE SYSTEM Flashcards

1
Q

Refers primarily to anatomical,
cellular, and humoral defenses that
functions in the early stages of host
defense

A

Innate Immunity/Non-specific Immunity
(1st and 2nd Line of Defense)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Second line of defense:
Enumerate the cellular factors

A
  1. Phagocytes
  2. Basophils & Mast Cells
  3. NK cells
  4. APCs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Second line of defense:
Enumerate the non-cellular factors

A
  1. Complement System
  2. Cytokines
  3. INF
  4. Inflammatory reactions
  5. Acute reactants
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Low ph of stomach and vagina

A

Acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Example of flushing actions

A

blinking of eyelids
peristalsis
urination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Enumerate the Secretion of Factors

A
  1. Interleukin 1
  2. Interleukin 6
  3. Complement
  4. Hydrolytic enzymes
  5. Tumor necrosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

promotes inflammatory response

A

Interleukin 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

promotes innate immunity

A

Interleukin 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

promotes elimination of pathogens
through cell lysis

A

Complement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

promotes inflammatory
response

A

Hydrolytic enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

kills tumor cells

A

Tumor necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Increase rapidly due to infection, injury, or
trauma to the tissues

A

Acute Phase Reactants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acute phase reactants are Produced primarily by

A

hepatocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

(liver parenchymal cells) within 12 to 24 hours
in response to an increase in certain
intercellular signaling polypeptides called

A

cytokinesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Other name for IFN-alpha

A

Leukocyte IFN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Primary producers of IFN alpha

A

Null lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Other name for IFN-beta

A

Epithelial
Fibroblast IFN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Primary producers of IFN beta

A

Fibroblasts, epithelial cells, MACs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Function of IFN beta

A

Anti-viral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Other name for IFN-gamma

A

Immune IFN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Primary producers of IFN-gamma

A

T helper 1 cells, T cytotoxic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Cells that engulf and digest foreign materials

A

Phagocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Examples of phagocytes are

A

Neutrophils (PMNs)
Monocytes
Macrophages
Dendritic cells
Fixed Phagocytes

24
Q

Locations of Macrophages (MACs):
Histocytes

A

Connective tissue

25
Locations of Macrophages (MACs): Alveolar MACs
lungs
26
Locations of Macrophages (MACs): Kupffer cells
liver
27
Locations of Macrophages (MACs): Littoral cell
Spleen
28
Locations of Macrophages (MACs): Mesangial cells
kidney
29
Locations of Macrophages (MACs): Microglia
brain
30
Locations of Macrophages (MACs): Osteoclasts
Bone
31
Locations of Macrophages (MACs): Synovial A cells
Synovial fluid
32
Locations of Macrophages (MACs): Hof-Bauer cells
Placenta
33
Locations of Macrophages (MACs): Langerhans cells
Epidermis
34
Indirect interaction: It is the enhancement of phagocytosis (C3b, IgG1 and IgG3)
Opsonization
35
Direct interaction: Pattern Recognition Receptors (PRRs): phagocytes use their PRRs to recognize and adhere to ______
Pathogen Associater Molecular Patterns (PAMPS)
36
Transcribe PRPs
Pattern Recognition Receptors (PRRs)
37
Ingestion (Engulfment): Vacuole + Pathogen = ________
PHAGOSOME
38
Example of oxygen dependent mechanisms which are toxic reactive oxygen intermediates
Superoxide anion Hydrogen peroxide Hydroxyl radical
39
Example of oxygen dependent mechanisms which are myeloperoxidase
Hypochlorite and highly toxic substances
40
Oxygen Independent Mechanisms: It has an antibiotic like peptides made by phagocytes
Defensins
41
Example of digestive enzymes
Lysozymes and lactoferrin
42
NK cells that Exist in the body at birth
Nonspecific Immunity
43
NK cells that are not produced by immunologic insult
Nonspecific Immunity
43
Transcribe ADCC
Antibody Dependent Cellular Cytotoxicity
44
NK cells Form ______ in Sheep RBC
Rosette
45
NK Cells: Responsible for the NK cell exposed to IL-2 and IFN gamma
Lymphokine Activated Cell (LAK)
46
Transcribe LAK
Lymphokine Activated Cell (LAK)
47
Method of Killing Formation of Pores causing lysis
Perforins
48
Method of Killing Programmed Cell Death
Apoptosis
49
Overall response of the body after tissue damage or invasion infectious agent
Inflammation
50
Inflammation: Rubor
redness
51
Inflammation: Calor
heat
52
Inflammation: Tumor
swelling
53
Inflammation: Dolor
pain
54
Inflammation: Function Laesa
loss of function

IMMUNOLOGY AND SEROLOGY :) (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions