Ovarian cancer Flashcards
1
Q
peak age
A
60 years
2
Q
prognosis
A
poor due to late recognition
3
Q
pathophysiology
A
epithelial in origin 90%
70-80% serous carcinomas
distal end of Fallopian tube I site of origin
4
Q
risk factors
A
FH - BRCA 1 nd 2 gene
Many ovulations
Early menarche
Late menopause
Nulliparity
5
Q
Clinical features
A
abdominal distension and bloating
abdominal and pelvic pain
urinary symptoms e.g. Urgency
early satiety
diarrhoea
6
Q
Ix
A
Ca-125
US
diagnostic laparotomy
7
Q
Mx
A
surgery
platinum based chemotherapy
8
Q
prognosis
A
80% advanced disease presentation
stage 5 survival 46%
