outcomes of inflammation

Question 1

resolution

Answer 1

everyhtig back to normal

Question 2

ideal conditions for resolution

Answer 2

Good regenerative capacity (see lecture 2)
Minimal tissue damage / cell death
Quick elimination of the causative agent
Good vascular drainage to remove fluid and debris

Question 3

suppuration

Answer 3

formaiton of pus mixed with neutrophils, debris, bacteria etc

Question 4

what can happen to suupuration if it gets walled off

Answer 4

can form an abscess

Question 5

organisation

Answer 5

formation of granulation tissue

Question 6

what joins two edges of a wound otgeher in skin healing weakly then strongly

Answer 6

fibrin weakly then epidermal regrowth and ocllagen synthesis makes a stronger join

Question 7

can vascular smooth muscle cells regenerate

Answer 7

yes

Question 8

what is damaged muscle replaced by

Answer 8

scar tissuw

Question 9

how does the cellular exudate change in chronic inflammation

Answer 9

neutrophils are replaced with lymphoytes, plasma cells and macrophages

Question 10

which type of necrosis is likely to develop to chronic

Answer 10

suppurative

Question 11

lymphocytes

Answer 11

small purple dots

Question 12

plasma cells

Answer 12

fried eggs

Question 13

crophages

Answer 13

bigger blobby ones

Question 14

eosinophils

Answer 14

tomatos with sunglasses

Question 15

killer t cells -cd8

Answer 15

recruit other immune cells, cytotoxic function

Question 16

helpter t cells - cd4

Answer 16

activate killer t and plasma cells

Question 17

cytokines

Answer 17

small proteins which enhance cell mediated immunity and enhance antibody response

Question 18

function of cytokines

Answer 18

cell signalling, (interleukins, TNF), promoting chemotaxis (chemokines), anti viral defences (interferons), promote apoptosis (TNF

Question 19

granuloma

Answer 19

collection of histiocytes

Question 20

role of granuloma

Answer 20

trap bacteria and preventit from spreadign

Question 21

type of granulomas in tb

Answer 21

caseating

Question 22

type of granulomas in sarcoidosis

Answer 22

non caseating