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DTMH - Parasitology & Entomology Slides > Other protozoa > Flashcards

Other protozoa Flashcards

Trichomonas, Toxoplasmosis, Free-living amoebae

1
Q
  1. Name this parasite (size: 25 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name on drug used to treat infection with this parasite
  5. Name one common symptom of infection with this parasite
A
  1. Trichomonas vaginalis
  2. Trophozoite
  3. Pear-shaped trophozoite within the size range (7-30 um) for T. vaginalis with anterior (4) and posterior (1) flagella and a single large anterior nucleus containing chromatin granules and a small karyosome
  4. Metronidazole
  5. Vaginitis with purulent discharge
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2
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 33 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Trophozoite
  3. Cystic structure
    * Within the size range (10-25 um) for Acanthamoeba spp
    * Cysts with a wrinkled,porous outer wall and an inner polygonal wall
    * One nucleus and large chromosome
  4. Amphotericin B
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3
Q
  1. What disease is caused by this parasite (size: 3 um)?
  2. Name two possible organisms
  3. What is the lifecycle stage?
  4. State your reasons
  5. Name two drugs to treat this disease
A
  1. Microsporidiosis
  2. Microsporidium sp; Encephalitozoon sp.; Enterocytozoon sp.
  3. Spore
  4. Features:
    * Spores within size range (1-4 um) of organisms that cause microsporidiosis
    * Belt-like stripe in the center of the spore
  5. Albendazole, fumagillin
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4
Q
  1. Name this parasite
  2. State your reasons
  3. State one vector for this parasite to the genus level
  4. Name one intermediate host for the lifecycle of this parasite
  5. Name one drug regimen used to treat infection with this parasite
A
  1. Babesia spp.
  2. Features
    * Pleomorphic trophozoites (rings) that are vacuolated
    * Lack of malaria pigment
    * Extra-erythrocytic parasites
    * Tetrad formations (Maltese cross
    * Lack of malaria pigment
  3. Ixodes spp (Tick)
  4. Peromyscus leucopus (White footed deer mouse)
  5. Treatment
    * Atovaquone PLUS azithromycin; OR
    * Clindamycin PLUS quinine
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5
Q
  1. Name this parasite to the genus level (size: 18 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Cyst
  3. Cystic structure
    * Within the size range (10-25 um) for Acanthamoeba spp
    * Cysts with a wrinkled,porous outer wall and an inner polygonal wall
    * One nucleus and large chromosome
  4. Amphotericin B
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6
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 13 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

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7
Q
  1. Name this parasite (size: 11 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug regimen used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Unsporulated oocyst (singular)
  3. Single spherical unsporulated oocyst within the size range (10-12 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites
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8
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 12 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

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9
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 16 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

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10
Q
  1. Name this parasite to the genus level (size: 24 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Naegleria fowleri
  2. Trophozoite
  3. Ameboid trophozoite
    * Within size range (10-35 um) for N. fowleri trophozoites (usually 10-15 um if rounded)
    * Granular cytoplasm with many vacuoles
    * One nucleus with a large, dense karyosome
  4. Amphotericin B
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11
Q
  1. What disease is caused by this parasite (size: 2 um)?
  2. Name two possible organisms
  3. What is the lifecycle stage?
  4. State your reasons
  5. Name two drugs to treat this disease
A
  1. Microsporidiosis
  2. Microsporidium sp; Encephalitozoon sp.; Enterocytozoon sp.
  3. Spore
  4. Features:
    * Spores within size range (1-4 um) of organisms that cause microsporidiosis
    * Belt-like stripe in the center of the spore
  5. Albendazole, fumagillin
How well did you know this?
1
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12
Q
  1. Name this parasite (size: 11 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Sporulated oocyst
  3. Spherical oocyst containing 2 sporocysts within the size range (10-12 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites
How well did you know this?
1
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13
Q
  1. Name this parasite (size: 12 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name on drug used to treat infection with this parasite
  5. Name one common symptom of infection with this parasite
A
  1. Trichomonas vaginalis
  2. Trophozoite
  3. Pear-shaped trophozoite within the size range (7-30 um) for T. vaginalis with anterior (4) and posterior (1) flagella and a single large anterior nucleus containing chromatin granules and a small karyosome
  4. Metronidazole
  5. Vaginitis with purulent discharge
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14
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 14 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

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15
Q
  1. Name this parasite to the genus level (size: 49 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Trophozoite
  3. Pleomorphic structure
    * Within size range (15-60 um) for B. mandrillaris trophozoites
    * Long pseudopodia (broader than Acanthamoeba)
    * One nucleus with a large karyosome and no peripheral chromatin
  4. Amphotericin B
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16
Q
  1. Name this parasite (size: 20 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name on drug used to treat infection with this parasite
  5. Name one common symptom of infection with this parasite
A
  1. Trichomonas vaginalis
  2. Trophozoite
  3. Pear-shaped trophozoite within the size range (7-30 um) for T. vaginalis with anterior (4) and posterior (1) flagella and a single large anterior nucleus containing chromatin granules and a small karyosome
  4. Metronidazole
  5. Vaginitis with purulent discharge
How well did you know this?
1
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2
3
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5
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17
Q

A section of brain tissue is shown

  1. Name this parasite (size: 21 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Cyst
  3. Spherical cyst within the size range (5-50 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites

N.b Toxoplasma cysts are spherical in brain tissue but more elongated in cardiac and skeletal muscle

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18
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 24 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Cyst
  3. Cystic structure
    * Within the size range (10-25 um) for Acanthamoeba spp
    * Cysts with a wrinkled,porous outer wall and an inner polygonal wall
    * One nucleus and large chromosome
  4. Amphotericin B
How well did you know this?
1
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2
3
4
5
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19
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 13 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Naegleria fowleri
  2. Trophozoite
  3. Ameboid trophozoite
    * Within size range (10-35 um) for N. fowleri trophozoites (usually 10-15 um if rounded)
    * Granular cytoplasm with many vacuoles
    * One nucleus with a large, dense karyosome
  4. Amphotericin B
20
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 17 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

21
Q
  1. Name this parasite (size: 18 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name on drug used to treat infection with this parasite
  5. Name one common symptom of infection with this parasite
A
  1. Trichomonas vaginalis
  2. Trophozoite
  3. Pear-shaped trophozoite within the size range (7-30 um) for T. vaginalis with anterior (4) and posterior (1) flagella and a single large anterior nucleus containing chromatin granules and a small karyosome
  4. Metronidazole
  5. Vaginitis with purulent discharge
22
Q
  1. Name this parasite to the genus level (size: 23 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Naegleria fowleri
  2. Trophozoite
  3. Ameflagellate trophozoite
    * Within size range (10-35 um) for N. fowleri trophozoites (usually 10-15 um if rounded)
    * Granular cytoplasm with many vacuoles
    * One nucleus with a large, dense karyosome
  4. Amphotericin B
23
Q
  1. Name this parasite to the genus level (size: 15 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Naegleria fowleri
  2. Trophozoite
  3. Ameboid trophozoite
    * Within size range (10-35 um) for N. fowleri trophozoites (usually 10-15 um if rounded)
    * Granular cytoplasm with many vacuoles
    * One nucleus with a large, dense karyosome
  4. Amphotericin B
24
Q
  1. Name this parasite
  2. State your reasons
  3. State one vector for this parasite to the genus level
  4. Name one intermediate host for the lifecycle of this parasite
  5. Name one drug regimen used to treat infection with this parasite
A
  1. Babesia spp.
  2. Features
    * Pleomorphic trophozoites (rings) that are vacuolated
    * Lack of malaria pigment
    * Extra-erythrocytic parasites
    * Tetrad formations (Maltese cross
    * Lack of malaria pigment
  3. Ixodes spp (Tick)
  4. Peromyscus leucopus (White footed deer mouse)
  5. Treatment
    * Atovaquone PLUS azithromycin; OR
    * Clindamycin PLUS quinine
25
Q
  1. What disease is caused by this parasite (size: 1 um)?
  2. Name two possible organisms
  3. What is the lifecycle stage?
  4. State your reasons
  5. Name two drugs to treat this disease
A
  1. Microsporidiosis
  2. Microsporidium sp; Encephalitozoon sp.; Enterocytozoon sp.
  3. Spore
  4. Features:
    * Spores within size range (1-4 um) of organisms that cause microsporidiosis
    * Belt-like stripe in the center of the spore
  5. Albendazole, fumagillin
26
Q
  1. Name this parasite (size: 11 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug regimen used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Sporulated oocyst
  3. Spherical oocyst containing 2 sporocysts within the size range (10-12 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites
27
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 23 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Cyst
  3. Cystic structure
    * Within the size range (10-25 um) for Acanthamoeba spp
    * Cysts with a wrinkled,porous outer wall and an inner polygonal wall
    * One nucleus and large chromosome
  4. Amphotericin B
28
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 21 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

29
Q
  1. Name this parasite to the genus level (size: 25 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Trophozoite
  3. Pleomorphic trophozoite
    * Within the size range (15-45 um) for Acanthamoeba spp trophozoites
    * Contain multiple spine-like processes (acanthopodia)
    * One nucleus and large centrally located chromosome
  4. Amphotericin B
30
Q
  1. Name this parasite (size: 7 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug regimen used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Tachyzoites (trophozoites)
  3. Features:
    * Tachyzoites (trophozoites) within the size range (4-8 um) for Toxoplasma gondii
    * Tapered Anterior end
    * Blunt Posterior end
    * Large nucleus
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites
31
Q
  1. Name this parasite (size: 11 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug regimen used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Unsporulated oocyst (singular
  3. Single spherical unsporulated oocyst within the size range (10-12 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites
32
Q
  1. Name this parasite
  2. State your reasons
  3. State one vector for this parasite to the genus level
  4. Name one intermediate host for the lifecycle of this parasite
  5. Name one drug regimen used to treat infection with this parasite
A
  1. Babesia spp.
  2. Features
    * Pleomorphic trophozoites (rings) that are vacuolated
    * Lack of malaria pigment
    * Extra-erythrocytic parasites
    * Tetrad formations (Maltese cross
    * Lack of malaria pigment
  3. Ixodes spp (Tick)
  4. Peromyscus leucopus (White footed deer mouse)
  5. Treatment
    * Atovaquone PLUS azithromycin; OR
    * Clindamycin PLUS quinine
33
Q
  1. Name this parasite to the genus level (size: 17 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Naegleria fowleri
  2. Trophozoite
  3. Ameboid trophozoite
    * Within size range (10-35 um) for N. fowleri trophozoites (usually 10-15 um if rounded)
    * Granular cytoplasm with many vacuoles
    * One nucleus with a large, dense karyosome
  4. Amphotericin B
34
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 24 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

35
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 34 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Trophozoite
  3. Pleomorphic structure
    * Within size range (15-60 um) for B. mandrillaris trophozoites
    * Long pseudopodia (broader than Acanthamoeba)
    * One nucleus with a large karyosome and no peripheral chromatin
  4. Amphotericin B
36
Q
  1. Name this parasite
  2. State your reasons
  3. State one vector for this parasite to the genus level
  4. Name one intermediate host for the lifecycle of this parasite
  5. Name one drug regimen used to treat infection with this parasite
A
  1. Babesia spp.
  2. Features
    * Pleomorphic trophozoites (rings) that are vacuolated
    * Lack of malaria pigment
    * Extra-erythrocytic parasites
    * Tetrad formations (Maltese cross
    * Lack of malaria pigment
  3. Ixodes spp (Tick)
  4. Peromyscus leucopus (White footed deer mouse)
  5. Treatment
    * Atovaquone PLUS azithromycin; OR
    * Clindamycin PLUS quinine
37
Q
  1. Name this parasite (size: 11 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug regimen used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Unsporulated oocyst (singular)
  3. Single spherical unsporulated oocyst within the size range (10-12 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites
38
Q
  1. Name this parasite (size: 19 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name on drug used to treat infection with this parasite
  5. Name one common symptom of infection with this parasite
A
  1. Trichomonas vaginalis
  2. Trophozoite
  3. Pear-shaped trophozoite within the size range (7-30 um) for T. vaginalis with anterior (4) and posterior (1) flagella and a single large anterior nucleus containing chromatin granules and a small karyosome
  4. Metronidazole
  5. Vaginitis with purulent discharge
39
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 22 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Cyst
  3. Cystic structure
    * Within the size range (10-25 um) for Acanthamoeba spp
    * Cysts with a wrinkled,porous outer wall and an inner polygonal wall
    * One nucleus and large chromosome
  4. Amphotericin B
40
Q
  1. Name this parasite (size: 22 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name on drug used to treat infection with this parasite
  5. Name one common symptom of infection with this parasite
A
  1. Trichomonas vaginalis
  2. Trophozoite
  3. Pear-shaped trophozoite within the size range (7-30 um) for T. vaginalis with anterior (4) and posterior (1) flagella and a single large anterior nucleus containing chromatin granules and a small karyosome
  4. Metronidazole
  5. Vaginitis with purulent discharge
41
Q
  1. Name this parasite
  2. State your reasons
  3. State one vector for this parasite to the genus level
  4. Name one intermediate host for the lifecycle of this parasite
  5. Name one drug regimen used to treat infection with this parasite
A
  1. Babesia spp.
  2. Features
    * Pleomorphic trophozoites (rings) that are vacuolated
    * Lack of malaria pigment
    * Extra-erythrocytic parasites
    * Tetrad formations (Maltese cross
    * Lack of malaria pigment
  3. Ixodes spp (Tick)
  4. Peromyscus leucopus (White footed deer mouse)
  5. Treatment
    * Atovaquone PLUS azithromycin; OR
    * Clindamycin PLUS quinine
42
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 25 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Trophozoite
  3. Pleomorphic structure
    * Within size range (15-60 um) for B. mandrillaris trophozoites
    * Long pseudopodia (broader than Acanthamoeba)
    * One nucleus with a large karyosome and no peripheral chromatin
  4. Amphotericin B
43
Q
  1. Name this parasite (size: 33 um)
  2. What is the lifecycle stage
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
  5. Name one definitive host for this parasite
  6. Name one method of transmission for human infection
A
  1. Toxoplasma gondii
  2. Cyst
  3. Spherical cyst within the size range (5-50 um) for T. gondii
  4. Treatment for retinochoiroditis, congenital, and encephalitis
    * Pyramethamine, PLUS
    * Sulfadiazine; PLUS
    * Folinic acid (not folic acid), PLUS
    * Add Prednisone for retinochoiroiditis and congenital infection
  5. Cats (felids)
  6. Consumption of food/water contaminated with sporulated oocysts, through contact with cat feces, or consumption of meat infected with trophozoites

N.b Toxoplasma cysts are spherical in brain tissue but more elongated in cardiac and skeletal muscle

44
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 17 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Balamuthia mandrillaris
  2. Cyst
  3. Cystic structure
    * Within size range (10-25 um) for B. mandrillaris cysts
    * Two walls with wrinkled fibrous outer wall and polygonal inner wall
    * One nucleus with a large karyosome
  4. Amphotericin B

N.b. morphologicall cannot distinguish between Balamuthia and Acanthamoebae cysts

45
Q

A histological section of brain tissue is shown

  1. Name this parasite to the genus level (size: 27 um)
  2. What is the lifecycle stage?
  3. State your reasons
  4. Name one drug used to treat infection with this parasite
A
  1. Acanthamoebae spp.
  2. Trophozoite
  3. Pleomorphic trophozoite
    * Within the size range (15-45 um) for Acanthamoeba spp trophozoites
    * Contain multiple spine-like processes (acanthopodia)
    * One nucleus and large centrally located chromosome
  4. Amphotericin B

DTMH - Parasitology & Entomology Slides (20 decks)

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