Filarial nematodes Flashcards

1
Q
  1. Name this parasite (size: 190 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella perstans
  2. Characteristic microfilaria
    * Within the size range (190-200 um) for stained M. perstans microfilaria
    * Unsheathed
    * Tail is blunt
    * Nuclei extend to the tip of the tail
  3. Culicoides (Midge)
  4. Diethylcarbamazine (21d) and mebendazole (28d)

N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective

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2
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Loa loa
  2. Characteristic microfilaria
    * Within the size range (230-250 um) for stained L. loa microfilaria
    * Presence of a sheath
    * Tail that tapers to a point and nuclei extend to the tip of the tail
  3. Chrysops sp (Deer fly)
  4. Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
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3
Q
  1. Name this parasite (size: 200 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella ozzardi
  2. Characteristic microfilaria
    * Within the size range (160-205 um) for stained M. ozzardi microfilaria
    * Unsheathed
    * Tail tapers to a point (often bent in a hook)
    * Nuclei do not extend to the tip of the tail
  3. Culicoides sp. (Midge), Simulium sp. (Black fly)
  4. Ivermectin (single dose)

N.b. M. ozzardi is only found in New World

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4
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Loa loa
  2. Characteristic microfilaria
    * Within the size range (230-250 um) for stained L. loa microfilaria
    * Presence of a sheath
    * Tail that tapers to a point and nuclei extend to the tip of the tail
  3. Chrysops sp (Deer fly)
  4. Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
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5
Q

A histological section of skin is shown

  1. Name this parasite (size: 312 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Onchocerca volvulus
  2. Characteristic microfilaria
    * Within the size range (300-315 um) for stained O. volvulus microfilaria
    * Unsheathed
    * Tail that tapers to a point (often sharply bent)
    * Nuclei do not extend to the tip of the tail
  3. Simulium sp (Black fly)
  4. Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
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6
Q
  1. Name this parasite (size: 230 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia malayi
  2. Characteristic microfilaria
    * Within the size range (175-230 um) for stained B. malayi microfilaria
    * Sheath that stains
    * Significant gap between terminal and sub-terminal nuclei
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
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7
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Loa loa
  2. Characteristic microfilaria
    * Within the size range (230-250 um) for stained L. loa microfilaria
    * Presence of a sheath
    * Tail that tapers to a point and nuclei extend to the tip of the tail
  3. Chrysops sp (Deer fly)
  4. Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
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8
Q

A histological section of skin is shown

  1. Name this parasite (size: 306 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Onchocerca volvulus
  2. Characteristic microfilaria
    * Within the size range (300-315 um) for stained O. volvulus microfilaria
    * Unsheathed
    * Tail that tapers to a point (often sharply bent)
    * Nuclei do not extend to the tip of the tail
  3. Simulium sp (Black fly)
  4. Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
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9
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Loa loa
  2. Characteristic microfilaria
    * Within the size range (230-250 um) for stained L. loa microfilaria
    * Presence of a sheath
    * Tail that tapers to a point and nuclei extend to the tip of the tail
  3. Chrysops sp (Deer fly)
  4. Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
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10
Q
  1. Name this parasite (size: 200 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella ozzardi
  2. Characteristic microfilaria
    * Within the size range (160-205 um) for stained M. ozzardi microfilaria
    * Unsheathed
    * Tail tapers to a point (often bent in a hook)
    * Nuclei do not extend to the tip of the tail
  3. Culicoides sp. (Midge), Simulium sp. (Black fly)
  4. Ivermectin (single dose)

N.b. M. ozzardi is only found in New World

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11
Q
  1. Name this parasite (size: 309 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Onchocerca volvulus
  2. Characteristic microfilaria
    * Within the size range (300-315 um) for stained O. volvulus microfilaria
    * Unsheathed
    * Tail that tapers to a point (often sharply bent)
    * Nuclei do not extend to the tip of the tail
  3. Simulium sp (Black fly)
  4. Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
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12
Q
  1. Name this parasite (size: 190 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia malayi
  2. Characteristic microfilaria
    * Within the size range (175-230 um) for stained B. malayi microfilaria
    * Sheath that stains
    * Significant gap between terminal and sub-terminal nuclei
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
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13
Q

A histological section of a worm retrieved from a skin nodule is shown

  1. Name this parasite
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Onchocerca volvulus
  2. Characteristic microfilaria
    * Within the size range (300-315 um) for stained O. volvulus microfilaria
    * Unsheathed
    * Tail that tapers to a point (often sharply bent)
    * Nuclei do not extend to the tip of the tail
  3. Simulium sp (Black fly)
  4. Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
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14
Q
  1. Name this parasite (size: 200 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella perstans
  2. Characteristic microfilaria
    * Within the size range (190-200 um) for stained M. perstans microfilaria
    * Unsheathed
    * Tail is blunt
    * Nuclei extend to the tip of the tail
  3. Culicoides (Midge)
  4. Diethylcarbamazine (21d) and mebendazole (28d)

N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective

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15
Q
  1. Name this parasite (size: 198 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella perstans
  2. Characteristic microfilaria
    * Within the size range (190-200 um) for stained M. perstans microfilaria
    * Unsheathed
    * Tail is blunt
    * Nuclei extend to the tip of the tail
  3. Culicoides (Midge)
  4. Diethylcarbamazine (21d) and mebendazole (28d)

N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective

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16
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Wuchereria bancrofti
  2. Characteristic microfilaria
    * Within the size range (240-300 um) for stained W. bancrofti microfilaria
    * *Sheathed *
    * Tail taper to a point
    * Individually visualized cells that do not extend to the tip of the tail
    * Loosely packed nuclear column
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
17
Q
  1. Name this parasite (size: 242 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Wuchereria bancrofti
  2. Characteristic microfilaria
    * Within the size range (240-300 um) for stained W. bancrofti microfilaria
    * *Sheathed *
    * Tail taper to a point
    * Individually visualized cells that do not extend to the tip of the tail
    * Loosely packed nuclear column
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
18
Q
  1. Name this parasite (size: 195 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella perstans
  2. Characteristic microfilaria
    * Within the size range (190-200 um) for stained M. perstans microfilaria
    * Unsheathed
    * Tail is blunt
    * Nuclei extend to the tip of the tail
  3. Culicoides (Midge)
  4. Diethylcarbamazine (21d) and mebendazole (28d)

N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective

19
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Loa loa
  2. Characteristic microfilaria
    * Within the size range (230-250 um) for stained L. loa microfilaria
    * Presence of a sheath
    * Tail that tapers to a point and nuclei extend to the tip of the tail
  3. Chrysops sp (Deer fly)
  4. Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
20
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Wuchereria bancrofti
  2. Characteristic microfilaria
    * Within the size range (240-300 um) for stained W. bancrofti microfilaria
    * *Sheathed *
    * Tail taper to a point
    * Individually visualized cells that do not extend to the tip of the tail
    * Loosely packed nuclear column
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
21
Q
  1. Name this parasite (size: 309 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia timori
  2. Characteristic microfilaria
    * Within the size range (average 310 um) for stained B. timori microfilaria
    * Sheath that does not stain
    * Large number of single file nuclei to the tip of the tail
    * Long cephalic space
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
22
Q

A histological section of skin is shown

  1. Name this parasite (size: 303 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Onchocerca volvulus
  2. Characteristic microfilaria
    * Within the size range (300-315 um) for stained O. volvulus microfilaria
    * Unsheathed
    * Tail that tapers to a point (often sharply bent)
    * Nuclei do not extend to the tip of the tail
  3. Simulium sp (Black fly)
  4. Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
23
Q

A histological section of skin is shown

  1. Name this parasite (size: 305 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Onchocerca volvulus
  2. Characteristic microfilaria
    * Within the size range (300-315 um) for stained O. volvulus microfilaria
    * Unsheathed
    * Tail that tapers to a point (often sharply bent)
    * Nuclei do not extend to the tip of the tail
  3. Simulium sp (Black fly)
  4. Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
24
Q
  1. Name this parasite (size: 200 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella ozzardi
  2. Characteristic microfilaria
    * Within the size range (160-205 um) for stained M. ozzardi microfilaria
    * Unsheathed
    * Tail tapers to a point (often bent in a hook)
    * Nuclei do not extend to the tip of the tail
  3. Culicoides sp. (Midge), Simulium sp. (Black fly)
  4. Ivermectin (single dose)

N.b. M. ozzardi is only found in New World

25
Q
  1. Name this parasite (size: 312 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia timori
  2. Characteristic microfilaria
    * Within the size range (average 310 um) for stained B. timori microfilaria
    * Sheath that does not stain
    * Large number of single file nuclei to the tip of the tail
    * Long cephalic space
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
26
Q
  1. Name this parasite (size: 200 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella streptocerca
  2. Characteristic microfilaria
    * Within the size range (180-240 um) for stained M. streptocerca microfilaria
    * Unsheathed
    * Tail is bent in a hook
    * Nuclei extend to the tip of the tail
  3. Culicoides sp. (Midge)
  4. Diethylcarbamazine, Ivermectin (single dose)
27
Q
  1. Name this parasite (size: 250 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Loa loa
  2. Characteristic microfilaria
    * Within the size range (230-250 um) for stained L. loa microfilaria
    * Presence of a sheath
    * Tail that tapers to a point and nuclei extend to the tip of the tail
  3. Chrysops sp (Deer fly)
  4. Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
28
Q
  1. Name this parasite (size: 310 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia timori
  2. Characteristic microfilaria
    * Within the size range (average 310 um) for stained B. timori microfilaria
    * Sheath that does not stain
    * Large number of single file nuclei to the tip of the tail
    * Long cephalic space
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
29
Q
  1. Name this parasite (size: 210 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia malayi
  2. Characteristic microfilaria
    * Within the size range (175-230 um) for stained B. malayi microfilaria
    * Sheath that stains
    * Significant gap between terminal and sub-terminal nuclei
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
30
Q
  1. Name this parasite (size: 245 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Wuchereria bancrofti
  2. Characteristic microfilaria
    * Within the size range (240-300 um) for stained W. bancrofti microfilaria
    * *Sheathed *
    * Tail taper to a point
    * Individually visualized cells that do not extend to the tip of the tail
    * Loosely packed nuclear column
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
31
Q
  1. Name this parasite (size: 195 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Mansonella streptocerca
  2. Characteristic microfilaria
    * Within the size range (180-240 um) for stained M. streptocerca microfilaria
    * Unsheathed
    * Tail is bent in a hook
    * Nuclei extend to the tip of the tail
  3. Culicoides sp. (Midge)
  4. Diethylcarbamazine, Ivermectin (single dose)
32
Q
  1. Name this parasite (size: 308 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Brugia timori
  2. Characteristic microfilaria
    * Within the size range (average 310 um) for stained B. timori microfilaria
    * Sheath that does not stain
    * Large number of single file nuclei to the tip of the tail
    * Long cephalic space
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin
33
Q
  1. Name this parasite (size: 247 um)
  2. State your reasons
  3. Name one vector for this parasite
  4. Name one drug regimen used to treat infection with this parasite
A
  1. Wuchereria bancrofti
  2. Characteristic microfilaria
    * Within the size range (240-300 um) for stained W. bancrofti microfilaria
    * *Sheathed *
    * Tail taper to a point
    * Individually visualized cells that do not extend to the tip of the tail
    * Loosely packed nuclear column
  3. Anopheles sp, Aedes sp
  4. Albendazole with Diethylcarbamazine; Albendazole with ivermectin