Filarial nematodes Flashcards
- Name this parasite (size: 190 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Mansonella perstans
- Characteristic microfilaria
* Within the size range (190-200 um) for stained M. perstans microfilaria
* Unsheathed
* Tail is blunt
* Nuclei extend to the tip of the tail - Culicoides (Midge)
- Diethylcarbamazine (21d) and mebendazole (28d)
N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective
- Name this parasite (size: 250 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Loa loa
- Characteristic microfilaria
* Within the size range (230-250 um) for stained L. loa microfilaria
* Presence of a sheath
* Tail that tapers to a point and nuclei extend to the tip of the tail - Chrysops sp (Deer fly)
- Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
- Name this parasite (size: 200 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Mansonella ozzardi
- Characteristic microfilaria
* Within the size range (160-205 um) for stained M. ozzardi microfilaria
* Unsheathed
* Tail tapers to a point (often bent in a hook)
* Nuclei do not extend to the tip of the tail - Culicoides sp. (Midge), Simulium sp. (Black fly)
- Ivermectin (single dose)
N.b. M. ozzardi is only found in New World
- Name this parasite (size: 250 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Loa loa
- Characteristic microfilaria
* Within the size range (230-250 um) for stained L. loa microfilaria
* Presence of a sheath
* Tail that tapers to a point and nuclei extend to the tip of the tail - Chrysops sp (Deer fly)
- Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
A histological section of skin is shown
- Name this parasite (size: 312 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Onchocerca volvulus
- Characteristic microfilaria
* Within the size range (300-315 um) for stained O. volvulus microfilaria
* Unsheathed
* Tail that tapers to a point (often sharply bent)
* Nuclei do not extend to the tip of the tail - Simulium sp (Black fly)
- Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
- Name this parasite (size: 230 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Brugia malayi
- Characteristic microfilaria
* Within the size range (175-230 um) for stained B. malayi microfilaria
* Sheath that stains
* Significant gap between terminal and sub-terminal nuclei - Anopheles sp, Aedes sp
- Albendazole with Diethylcarbamazine; Albendazole with ivermectin
- Name this parasite (size: 250 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Loa loa
- Characteristic microfilaria
* Within the size range (230-250 um) for stained L. loa microfilaria
* Presence of a sheath
* Tail that tapers to a point and nuclei extend to the tip of the tail - Chrysops sp (Deer fly)
- Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
A histological section of skin is shown
- Name this parasite (size: 306 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Onchocerca volvulus
- Characteristic microfilaria
* Within the size range (300-315 um) for stained O. volvulus microfilaria
* Unsheathed
* Tail that tapers to a point (often sharply bent)
* Nuclei do not extend to the tip of the tail - Simulium sp (Black fly)
- Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
- Name this parasite (size: 250 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Loa loa
- Characteristic microfilaria
* Within the size range (230-250 um) for stained L. loa microfilaria
* Presence of a sheath
* Tail that tapers to a point and nuclei extend to the tip of the tail - Chrysops sp (Deer fly)
- Diethylcarbamazine if microfilaremia is <8000; If >8000, albendazole to decrease loads followed by Diethylcarbamazine. Ivermectin may also be used prior to DEC if microfilarial loads are low
- Name this parasite (size: 200 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Mansonella ozzardi
- Characteristic microfilaria
* Within the size range (160-205 um) for stained M. ozzardi microfilaria
* Unsheathed
* Tail tapers to a point (often bent in a hook)
* Nuclei do not extend to the tip of the tail - Culicoides sp. (Midge), Simulium sp. (Black fly)
- Ivermectin (single dose)
N.b. M. ozzardi is only found in New World
- Name this parasite (size: 309 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Onchocerca volvulus
- Characteristic microfilaria
* Within the size range (300-315 um) for stained O. volvulus microfilaria
* Unsheathed
* Tail that tapers to a point (often sharply bent)
* Nuclei do not extend to the tip of the tail - Simulium sp (Black fly)
- Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
- Name this parasite (size: 190 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Brugia malayi
- Characteristic microfilaria
* Within the size range (175-230 um) for stained B. malayi microfilaria
* Sheath that stains
* Significant gap between terminal and sub-terminal nuclei - Anopheles sp, Aedes sp
- Albendazole with Diethylcarbamazine; Albendazole with ivermectin
A histological section of a worm retrieved from a skin nodule is shown
- Name this parasite
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Onchocerca volvulus
- Characteristic microfilaria
* Within the size range (300-315 um) for stained O. volvulus microfilaria
* Unsheathed
* Tail that tapers to a point (often sharply bent)
* Nuclei do not extend to the tip of the tail - Simulium sp (Black fly)
- Ivermectin, doxycycline, Moxidectin (similar to ivermectin)
- Name this parasite (size: 200 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Mansonella perstans
- Characteristic microfilaria
* Within the size range (190-200 um) for stained M. perstans microfilaria
* Unsheathed
* Tail is blunt
* Nuclei extend to the tip of the tail - Culicoides (Midge)
- Diethylcarbamazine (21d) and mebendazole (28d)
N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective
- Name this parasite (size: 198 um)
- State your reasons
- Name one vector for this parasite
- Name one drug regimen used to treat infection with this parasite
- Mansonella perstans
- Characteristic microfilaria
* Within the size range (190-200 um) for stained M. perstans microfilaria
* Unsheathed
* Tail is blunt
* Nuclei extend to the tip of the tail - Culicoides (Midge)
- Diethylcarbamazine (21d) and mebendazole (28d)
N.b. no periodicity for M. perstans and adults reside in serous fluids e.g. peritoneal cavities. Single dose clearance regiimens are not effective