OTH: Cancer Flashcards
Etiology (5)
Environmental carcinogens Viral carcinogens Genetic Dietary Chronic stress
Early warning signs:
- Unusual ______/_______
- Lump, _______
- Sore that does not _____
- Change in _____/_____
- A cough that is _____, and ______
- Indigestion and dysphagia
- Change in size/appearance of ______
- Unexplained weight ____
- Bleeding/discharge
- Thickening
- Heal
- Bowel/bladder
- Hoarse and persistent
- Mole
- Loss
Tumor/neoplasm: abnormal growth of ____ ____ that is _______. Competes for vital blood supply and nutrients
New tissue
Nonfunctional
Benign tumor: localized, ___ growing, usually encapsulated. Noninvasive
Slow
Malignant tumor: INVASIVE, _____ growth. And usually mets.
Rapid
5 types of malignant tumors?
Carcinoma Sarcoma Lymphoma Leukemia Myeloma
This tumor originates in the EPITHELIAL tissue (skin, stomach, breast, rectum, colon).
Carcinoma
Carcinoma in situ is a ________ neoplasm that has not invaded basement membrane
Premalignant
The tumor originates in CT and mesodermal tissue (muscle, bone, fat)
Sarcoma
This tumor affects lymphatic system
Lymphoma
These tumors affect blood and blood forming organs
Leukemia
Myeloma
CA staging is based on what 3 factors?
Primary tumor (T) Regional lymph node involvement (N) And mets (M)
Stage 0 is what?
Carcinoma in situ
Stage 1 is what?
Tumor localized
2 cm or less
Not spread to (N)
Stage 2 is what?
Tumor locally advanced
2-5 cm
With or without (n) involvement
Stage 3 is what?
Tumor is locally more advanced Spread to (n)
Stage 4 is what?
Tumor has METS, or spread to other organs
Grade 1 (low grade): CA cells resemble \_\_\_\_\_ cells (well differentiated), \_\_\_ growing
Normal
Slow
Grade 2 (immediate grade): CA cells look more _____ (mod differentiated) and are growing _____ _____
Abn
Slightly faster
Grade 3 (high grade): CA cells are ____ (poorly differentiated)/ spread more _______
Abn
Aggressively
Grade 4 (high grade): CA cells are ____ (undifferentiated)
Abn
Cured means that there is no recurrence within __ years post-tx
5
Medical management includes what?
Surgery
Radiation
Chemo
Immunotherapy - interferons, interleukins, cytokines ; or stem cell transplant
Red Flag: Local and Systemic Effects:
Radiation:
Pain, fatigue, immunosuppression, FIBROSIS, BURNS, _______ wound healing, edema, _____ loss, CNS effects
Delayed
Hair