OTC Products Flashcards
Os-Cal
- SEs
Ca+ carbonate + Vit D3
- Vit D = cholecalciferol = skin makes when exposes to sun. 3x more effective than Vit D2
- SEs: constipation
- Best take with meals
Iron Supplement
- Dose
- Administration
Avoid given with:
Abs is enhanced with: - ADEs
- Dose: 100-200 mg elemental iron QD
- Administration: empty stomach with water = best abs. If become irritated, can take w/ food, but NOT with cereal, milk, tea, coffee, eggs or fibers. Abs is enhance with Vit C.
ADEs
- Constipation, diarrhea
- Heart burn, GI distress
- Black stools
- Oral sol’n can temporary staining of teeth
Tylenol
- Indication
- Dose for children
- Hydrated:
- Dehydrated
- Max
- Liquid Dosage form
- Adult dosing
- Max Dose:
R strength 325mg
Extra strength 500 mg
ER 650mg
Acetaminophen
- Indication: pain/fever, analgesic/antipyretic
Dose for children: Max: 75mg/kg.d
- Well hydrated child: 15mg/kg Q4-6H
- Dehydrated: 10mg/kg Q4-6H
- Dosage form: 160mg/5mL
Adult dosing
- 650 mg PO Q4-6H.
- Max Dose:
R strength 325mg: 3250mg/day
Extra strength 500 mg: 3g/d
ER 650mg: 3900mg/d
NAC
Acetadote
- Indication
- Dosing
- Duration
N-Acetylcysteine
Acetadote: IV form
- Indication: tx tylenol toxicity. Level > 150 indicates tx
Dosing
- 1st dose: NAC 140mg/kg up to 14g
- Subsequent doses: NAC 70mg/kg Q4H x 17 doses
- Duration: Standard course is 72H
ASA
- MOA/Dosing
- ADEs
- CI
- DDI
- Overdose
MOA/Dosing
- Anti-inflammatory effect: 4g/d max
- Analgesic effect: 650-1000mg Q4-6H
- Antipyretic: same as above
- Platelet effects: 81-325mg/d.
ADEs
- GI: PUD/GI bleeding
- CNS: salicylism
- Central respiratory effects: depression or apnea
- Uric acid change
- Asymptomatic hepatitis
- Renal insufficiency
- Hypersensitivity
CI
- Rey’s syndrome
- Gout hypersensitivity of ASA
- Active PUD
- Aspirin induced fetal or neonatal toxicity
DDI
- Ibuprofen: inactivates ASA’s anticoagulation effects => compete for the same preceptor
Overdose
- Activated charcoal
- Na bicarbonate to increase pH
NSAIDs
- MOA
- ADEs
- C/I
- MOA: blocks cyclooxygenase COX 1 and COX2
ADEs
- GI: #1
- Renal adverse events
- Bleeding risk
- HA
- CNS effects
C/I
- PUD
- Renal insufficency
- Bleeding risk
- Hypersensitivity
- Avoid in 3rd trimester (Cat B in 1st and 2nd; Cat C in 3rd)
Meclomen
- Indication
Meclofenamate
- NSAID
Voltaren
Voltaren Gel
Diclofenac
Diclofenac gel
- NSAIDs
Arthrotec
- Indication
- Avoid in
Diclofenac 50mg + Misoprostel 200mcg
- NSAID
- Preg Cat X
Cytotec
- Preg Cat
- Indication
Misoprostel:
- Preg Cat X
Indications:
- Prevention of NSAID-induced gastric ulcers
- Medical termination of pregnancy
Pennsaid
- Form
Diclofenac
- Form: Topical Sol’n
Flector
- Form
- Duration
Diclofenac
- Form: patch Q12H. Apply to most painful area
Maxicam
- Dosing frequency
Isoxicam
- Long half life: QD
- NSAID
Feldene
- Dosing frequency
Piroxicam
- Long half life: QD
- NSAID
Motrin
Ibuprofen
Duexis
Ibuprofen 800mg + famotidine 26.6mg TID
Naprosyn
- Dose
Naproxen
- Dose 500mg Q12H
- Lowest cardiovascular risk
Nalfon
- Indication
Fenoprofen
- OA, RA, mild to moderate pain
Orudis
- Indication
Ketoprofen
- Dysmenorrhea
- OA, RA
Daypro
- Indication
Oxaprozin
- OA, RA
Lodine
- Indication
Etodolac
- Acute pain
- OA, RA
Relafen
Nabumetone
Indocin
Indomethacin
Clinoril
Sulindac