IV Incompatibilities Flashcards
1
Q
Zovirax
- IV infusion length
- Reconstitute
- Sol’n for IV infusion
- Storage
A
Acyclovir
- IV infusion: over 1H to prevent renal damage
- Reconstitute: SW
- Sol’n for IV infusion: D5W, NS, LR
- Storage: do not refrigerate. Store at RT
2
Q
Ampicillin
- Reconstitute:
- Compatible w/:
A
- Reconstitute: SW
- Compatible w/: D5W, NS
3
Q
Cephalosproines
- Compatible w/:
- Storage:
- Renal adj:
- Liver adj:
- No adj:
A
Cefazoline: ancef Cefepime: maxipime Cefoperazone: cefobid Cefotetan: cefotan Cefoxitin: mefoxin Ceftazidime: fortaz Cetriaxone: rocephin Cefuroxime: zinacef
- Compatible w/: D5W, NS
- Storage: fridge
- Renal adj: all except cefoperazone and ceftriaxone
- Liver adj: cefoperazone
- No adj: ceftriaxone
4
Q
Ancef
- Dose
A
Cefazolin
- Usual IV dosage: 500mg to 1g IV Q8H
5
Q
Ceforbid
- Dose
A
Cefoperazone
- Dose: 12g or 4g per day for pts w/ advance liver cirrhosis
6
Q
Cefotan
- Dose
A
Cefotetan
- Dose: 1g Q12H
7
Q
Mefoxin
- Dose
A
Cefoxitin
- Dose: 1g Q6-8H
8
Q
Fortaz
- Dose
A
Ceftazidime
- IV dose: 1g IV Q8-12H
9
Q
Rocephin
- Dose
A
Ceftriaxone
- IV dose: 4g max/day
10
Q
Zinacef
- Dose
A
Cefuroxime
- Dose: 750 to 1.5g IV Q8H
11
Q
Primaxim
- Storage:
- Reconstitute:
A
Imipenem/Cilistatin
- Storage: fridge
- Reconstitute: NS
12
Q
Invanz
- Storage:
- Reconstitute:
A
Ertapenem
- Storage: fridge
- Reconstitute: NS
13
Q
Doribax
- Reconstitute:
A
Doripenem
- Reconstitute: NS, D5W
14
Q
Merrem
- Reconstitute:
A
Meropenem
- Reconstitute: NS, D5W
15
Q
Ciprofloxacin
- Reconstitute
- Storage
A
- Reconstitute: NS, D5W, SW, LR
- Storage: protect from light and RT
16
Q
Levofloxacin
- Reconstitute
- Storage
- Expiration for diluted sol’n
A
- Reconstitute: NS, D5W, SW, LR
- Storage: protect from light and RT
- Expiration for diluted sol’n: 72H RT, 14d fridge
17
Q
Vancomycin
- Compatible
- Expiration for diluted sol’n
A
- Compatible: D5W, NS
- Expiration for diluted sol’n: 24H RT, 14d fridge
18
Q
Cubicin
- Compatible
- Undiluted vial store in:
A
Daptomicin
- Compatible; NS
- Fridge
19
Q
Zyvox
- Compatible:
- Storage:
A
Linezolid
- Compatible: D5W
- Storage: RT
20
Q
Synercid
- Compatible
- Storage for unopened vial
A
Quinupristin/Dalfopristin
- Compatible: D5W
- Storage for unopened vial: fridge
- Do not shake to limit foam
21
Q
Bactrim
- Reconstitute
- Storage
- Dose: usual IV, PCP, UTI
- Dose base on:
- Renal adjust
A
- Reconstitute: D5W
- Storage: 6H RT, protect from light
Dose:
- Usual IV: 8-10mg/kg/d Q6,8,12H
- PCP: 15-20mg/kg/d
- UTI: 1DS tab BID
- Dose base on: Trimethoprim
- Renal adjust: yes when CrCl less than 30
22
Q
Flagyl
- Storage:
- Reconstitute
- Do not use needle contain
A
Metronidazole
- Storage: protect from light. Store in fridge = crystal may form. Dissolve on RT
- Reconstitute: NS
- Do not use needle contain: Aluminum. Cause med to discoloration
23
Q
Rifampin
- Reconstitute:
- Storage
A
- Reconstitute: D5W, NS
- Storage: protect from light
NS: 24H
D5W: 4H
24
Q
Amphotericin B
- Reconstitute:
- In-line filter
- Storage
- Final Concentration
A
- Reconstitute: D5W
- In-line filter for ampho B but not for lipid complex
- Storage: fridge, protect from light
- Final Concentration
- Do not exceed 0.1mg/mL fo peripheral
- Do not exceed 0.25mg/mL for central line
25
Amphotericin B Lipid Complex
- Reconstitute:
- In-line filter
- Storage
- Final Concentration
- Reconstitute: D5W
- In-line filter: No
- Storage: Fridge, protect from light
- Final Concentration: 1mg/mL
26
Candidas
- Reconstitue
- Vials storage
Caspofungin
- Reconstitue: NS
- Vials storage: fridge
27
Nitroglycerin
- Bottle:
- Storage of tab
- Use glass bottle
| - Storage of tab: protect from light
28
Nitroprusside
- Storage
- Reconstitute
- Storage: protect from light
| - Reconstitute: D5W. Use immediately
29
Amrinone
- Indication:
- Reconstitute:
Inamrinone
- Indication:
- Reconstitute: NS or 1/2NS
30
Diltiazem
- Storage
- Storage: fridge
31
Ativan
- Route:
- Storage:
- Reconstitute
- Inline:
Lorazepam
- Route: IV, IM
- Storage: fridge, protect from light
- Reconstitute: D5W, NS
- Inline filter w/ 0.22 micron
32
Amiodarone
- Storage
- Reconstitute
- Bag for infusion
- Dose for IV
- Storage: RT, protect from light
- Reconstitute: D5W (and NS at concentration 1.8-4mg/mL)
- Bag: PVC bag for up to 2H w/ 0.22 micron in-line filter. Rec dilute in glass
Dose:
- 150mg over 10 min
- 360mg over 6H
- 540mg over 18H
33
Gengraf
Neograf
Sandimmune
Restasis
- Indication
- Warning
- Sandimmune Injection
* Storage:
* Ampule:
* Reconstitute:
Cyclosporin
Indication
- Ppx for organ rejection
- Severe, active RA
- Severe, plaque psoriasis
- Increase tear production (Restasis)
Warning
- Nephrotoxicity
- Hepatotoxicity
- Sandimmune Injection
* Storage: RT
* Ampule: protect from light
* Reconstitute: D5W or NS
34
Sandostatin
- Indication:
- Storage for sol'n and suspension:
Octreotide
- Indication: Diarrhea associated with carcinoid tumors
- Storage for sol'n and suspension: Fridge
35
Diprivan
- Indication:
- C/I
- Storage
- Reconstitute
Propofol
- Indication: general anesthetic
- C/I: eggs, soy
- Storage: RT and protect from light
- Reconstitute: D5W
36
Anectine
- Indication
- Storage
Succinylcholine
- Indication: Neuromuscular blocking agent used adjunct to anesthesia to facilitate both rapid and routine endotracheal intubation and to relax skeletal muscle
- Storage: fridge
37
Dilantin
Dilantin Infatabs
Phenytek
Phenytoin Infatabs
- Storage:
- Reconstitute:
- Do not adm through
- Max rate:
Phenytoin
- Storage: RT
- Reconstitute: NS. DO NOT compatible w/ D5W
- Do not adm through PICC lines as it will precipitate and block line
- Max rate: 50mg/min
38
Fosphenytoin
- Storage:
- Reconstitute:
- Storage: fridge
| - Reconstitute: D5W, NS
39
Reopro
- Reconstitute
Abciximab
- Reconstitute: D5W or NS
40
Aggrastat
- Reconstitute
Tirofiban
- Reconstitute: D5W or NS
41
Integrillin
Eptifibatide
- Use directly from vial
42
Levothyroxine
- Storage:
- Reconstitute
- Shelf life after dilution
- Storage: RT, protect from light
- Reconstitute: NS
- Shelf life after dilution: very short therefore use immediately
