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PassNaplexNow - NAPLEX review prep > IV Incompatibilities > Flashcards

IV Incompatibilities Flashcards

1
Q

Zovirax

  • IV infusion length
  • Reconstitute
  • Sol’n for IV infusion
  • Storage
A

Acyclovir

  • IV infusion: over 1H to prevent renal damage
  • Reconstitute: SW
  • Sol’n for IV infusion: D5W, NS, LR
  • Storage: do not refrigerate. Store at RT
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2
Q

Ampicillin

  • Reconstitute:
  • Compatible w/:
A
  • Reconstitute: SW

- Compatible w/: D5W, NS

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3
Q

Cephalosproines

  • Compatible w/:
  • Storage:
  • Renal adj:
  • Liver adj:
  • No adj:
A 
Cefazoline: ancef
Cefepime: maxipime
Cefoperazone: cefobid
Cefotetan: cefotan
Cefoxitin: mefoxin
Ceftazidime: fortaz
Cetriaxone: rocephin
Cefuroxime: zinacef
  • Compatible w/: D5W, NS
  • Storage: fridge
  • Renal adj: all except cefoperazone and ceftriaxone
  • Liver adj: cefoperazone
  • No adj: ceftriaxone
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4
Q

Ancef

  • Dose
A

Cefazolin

  • Usual IV dosage: 500mg to 1g IV Q8H
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5
Q

Ceforbid

  • Dose
A

Cefoperazone

  • Dose: 12g or 4g per day for pts w/ advance liver cirrhosis
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6
Q

Cefotan

  • Dose
A

Cefotetan

  • Dose: 1g Q12H
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7
Q

Mefoxin

  • Dose
A

Cefoxitin

  • Dose: 1g Q6-8H
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8
Q

Fortaz

  • Dose
A

Ceftazidime

  • IV dose: 1g IV Q8-12H
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9
Q

Rocephin

  • Dose
A

Ceftriaxone

  • IV dose: 4g max/day
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10
Q

Zinacef

  • Dose
A

Cefuroxime

  • Dose: 750 to 1.5g IV Q8H
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11
Q

Primaxim

  • Storage:
  • Reconstitute:
A

Imipenem/Cilistatin

  • Storage: fridge
  • Reconstitute: NS
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12
Q

Invanz

  • Storage:
  • Reconstitute:
A

Ertapenem

  • Storage: fridge
  • Reconstitute: NS
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13
Q

Doribax

  • Reconstitute:
A

Doripenem

  • Reconstitute: NS, D5W
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14
Q

Merrem

  • Reconstitute:
A

Meropenem

  • Reconstitute: NS, D5W
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15
Q

Ciprofloxacin

  • Reconstitute
  • Storage
A
  • Reconstitute: NS, D5W, SW, LR

- Storage: protect from light and RT

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16
Q

Levofloxacin

  • Reconstitute
  • Storage
  • Expiration for diluted sol’n
A
  • Reconstitute: NS, D5W, SW, LR
  • Storage: protect from light and RT
  • Expiration for diluted sol’n: 72H RT, 14d fridge
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17
Q

Vancomycin

  • Compatible
  • Expiration for diluted sol’n
A
  • Compatible: D5W, NS

- Expiration for diluted sol’n: 24H RT, 14d fridge

18
Q

Cubicin

  • Compatible
  • Undiluted vial store in:
A

Daptomicin

  • Compatible; NS
  • Fridge
19
Q

Zyvox

  • Compatible:
  • Storage:
A

Linezolid

  • Compatible: D5W
  • Storage: RT
20
Q

Synercid

  • Compatible
  • Storage for unopened vial
A

Quinupristin/Dalfopristin

  • Compatible: D5W
  • Storage for unopened vial: fridge
  • Do not shake to limit foam
21
Q

Bactrim

  • Reconstitute
  • Storage
  • Dose: usual IV, PCP, UTI
  • Dose base on:
  • Renal adjust
A
  • Reconstitute: D5W
  • Storage: 6H RT, protect from light

Dose:

  • Usual IV: 8-10mg/kg/d Q6,8,12H
  • PCP: 15-20mg/kg/d
  • UTI: 1DS tab BID
  • Dose base on: Trimethoprim
  • Renal adjust: yes when CrCl less than 30
22
Q

Flagyl

  • Storage:
  • Reconstitute
  • Do not use needle contain
A

Metronidazole

  • Storage: protect from light. Store in fridge = crystal may form. Dissolve on RT
  • Reconstitute: NS
  • Do not use needle contain: Aluminum. Cause med to discoloration
23
Q

Rifampin

  • Reconstitute:
  • Storage
A
  • Reconstitute: D5W, NS
  • Storage: protect from light
    NS: 24H
    D5W: 4H
24
Q

Amphotericin B

  • Reconstitute:
  • In-line filter
  • Storage
  • Final Concentration
A
  • Reconstitute: D5W
  • In-line filter for ampho B but not for lipid complex
  • Storage: fridge, protect from light
  • Final Concentration
    • Do not exceed 0.1mg/mL fo peripheral
    • Do not exceed 0.25mg/mL for central line
25
Q

Amphotericin B Lipid Complex

  • Reconstitute:
  • In-line filter
  • Storage
  • Final Concentration
A
  • Reconstitute: D5W
  • In-line filter: No
  • Storage: Fridge, protect from light
  • Final Concentration: 1mg/mL
26
Q

Candidas

  • Reconstitue
  • Vials storage
A

Caspofungin

  • Reconstitue: NS
  • Vials storage: fridge
27
Q

Nitroglycerin

  • Bottle:
  • Storage of tab
A
  • Use glass bottle

- Storage of tab: protect from light

28
Q

Nitroprusside

  • Storage
  • Reconstitute
A
  • Storage: protect from light

- Reconstitute: D5W. Use immediately

29
Q

Amrinone

  • Indication:
  • Reconstitute:
A

Inamrinone

  • Indication:
  • Reconstitute: NS or 1/2NS
30
Q

Diltiazem

  • Storage
A
  • Storage: fridge
31
Q

Ativan

  • Route:
  • Storage:
  • Reconstitute
  • Inline:
A

Lorazepam

  • Route: IV, IM
  • Storage: fridge, protect from light
  • Reconstitute: D5W, NS
  • Inline filter w/ 0.22 micron
32
Q

Amiodarone

  • Storage
  • Reconstitute
  • Bag for infusion
  • Dose for IV
A
  • Storage: RT, protect from light
  • Reconstitute: D5W (and NS at concentration 1.8-4mg/mL)
  • Bag: PVC bag for up to 2H w/ 0.22 micron in-line filter. Rec dilute in glass

Dose:

  • 150mg over 10 min
  • 360mg over 6H
  • 540mg over 18H
33
Q

Gengraf
Neograf
Sandimmune
Restasis

  • Indication
  • Warning
  • Sandimmune Injection
    • Storage:
    • Ampule:
    • Reconstitute:
A

Cyclosporin

Indication

  • Ppx for organ rejection
  • Severe, active RA
  • Severe, plaque psoriasis
  • Increase tear production (Restasis)

Warning

  • Nephrotoxicity
  • Hepatotoxicity
  • Sandimmune Injection
    • Storage: RT
    • Ampule: protect from light
    • Reconstitute: D5W or NS
34
Q

Sandostatin

  • Indication:
  • Storage for sol’n and suspension:
A

Octreotide

  • Indication: Diarrhea associated with carcinoid tumors
  • Storage for sol’n and suspension: Fridge
35
Q

Diprivan

  • Indication:
  • C/I
  • Storage
  • Reconstitute
A

Propofol

  • Indication: general anesthetic
  • C/I: eggs, soy
  • Storage: RT and protect from light
  • Reconstitute: D5W
36
Q

Anectine

  • Indication
  • Storage
A

Succinylcholine

  • Indication: Neuromuscular blocking agent used adjunct to anesthesia to facilitate both rapid and routine endotracheal intubation and to relax skeletal muscle
  • Storage: fridge
37
Q

Dilantin
Dilantin Infatabs
Phenytek
Phenytoin Infatabs

  • Storage:
  • Reconstitute:
  • Do not adm through
  • Max rate:
A

Phenytoin

  • Storage: RT
  • Reconstitute: NS. DO NOT compatible w/ D5W
  • Do not adm through PICC lines as it will precipitate and block line
  • Max rate: 50mg/min
38
Q

Fosphenytoin

  • Storage:
  • Reconstitute:
A
  • Storage: fridge

- Reconstitute: D5W, NS

39
Q

Reopro

  • Reconstitute
A

Abciximab

  • Reconstitute: D5W or NS
40
Q

Aggrastat

  • Reconstitute
A

Tirofiban

  • Reconstitute: D5W or NS
41
Q

Integrillin

A

Eptifibatide

  • Use directly from vial
42
Q

Levothyroxine

  • Storage:
  • Reconstitute
  • Shelf life after dilution
A
  • Storage: RT, protect from light
  • Reconstitute: NS
  • Shelf life after dilution: very short therefore use immediately

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