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PassNaplexNow - NAPLEX review prep > Compounding > Flashcards

Compounding Flashcards

1
Q

advantage of a satellite pharmacy?

A

advantage is that the pharmacist is able to interact with other healthcare professionals and patients.

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2
Q

levigating agents/wetting agents for creams and ointments MUST BE….

A

compatible/miscible with the base

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3
Q

Levigation

A

“wet grinding’

process of reducing particle size of a solid (powder) by mixing it with a small amount of non-soluble liquid (this is the levigating agent)

consistency of putty/paste

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4
Q

Excessive heat defined as

A

> 40 C

(104 F)

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5
Q

What kind of compounding agent is:

Benzalkonium Cl

A

PRESERVATIVE

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6
Q

CARBOWAX is a name for

A

PEG

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7
Q

What kind of compounding agent is:

Cresol

A

PRESERVATIVE

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8
Q

What kind of compounding agent is:

SPAN 20, 40, 60

(sorbitan monolurate)

A

emulsifying agent

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9
Q

bulk balance/counter balance sensitivity

A

100mg

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10
Q

polyethylene monooleate is also known as?

A

PEG 400

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11
Q

What kind of compounding agent is:

Sodium Oleate

A

emulsifying agent

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12
Q

What kind of compounding agent is:

Sorbitan Stearate

A

emulsifying agent

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13
Q

What kind of compounding agent is:

Glycerol Monostearate

A

emulsifying agent

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14
Q

What kind of compounding agent is:

Polyglyceryl Oleate

A

emulsifying agent

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15
Q

What kind of compounding agent is:

Benzoic acid

A

PRESERVATIVE

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16
Q

What kind of compounding agent is:

Glycerol Monostearate

A

EMULSIFYING AGENT

(GMS)

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17
Q

Hydrocolloids are what type of agent?

A

Suspending agent

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18
Q

What kind of compounding agent is:

Benzethonium Cl

A

PRESERVATIVE

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19
Q

Freezer temp

A

-25 C to -10 C

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20
Q

The levigating agent must be _____ with the ointment base**

A

miscible

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21
Q

Parabens are?

A

Preservatives

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22
Q

What kind of compounding agent is:

Sodium Lauryl Sulfate

A

emulsifying agent

most H20 soluble

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23
Q

Which types of products need a “shake before use” auxillary label?

A
  1. suspensions
  2. lotions
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24
Q

What kind of compounding agent is:

Benzoic Acid

A

PRESERVATIVE

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25
Polyoxyethylene Sorbitan
TWEEN
26
Carbomers are
*gelling agents!*
27
What kind of compounding agent is: TWEEN
emulsifying agent
28
USP Regulation enforceable by the FDA apply to (6)
1. Ingredient Standards 2. Documentation and Record Keeping 3. Packaging and Storage 4. Facilities & Equipment 5. Quality Assurance & Quality Control 6. Personnel
29
polysorbate is
TWEEN
30
what's a satellite pharmacy?
a pharmacy that is located in a patient care area and where the medications for patients are prepared nearby away from the main (central) pharmacy location in a hospital. must be staffed by @ least _1 pharmacist_
31
A Class A or III prescription balance: maximum capacity
120 GRAMS
32
levigation is the mos commonly used method when
incorporating solids into an ointment or cream
33
A Class A or III prescription balance: Sensitivy requirement or readibility\*\*\*
must be ***at least 6 mg*** **(\<5% of 120 mg** - 120 mg being the max weight) this means: no less than 120 mg may be weighed on the balance to maintain an _error of \< 5%_ also means as much as 6 mg could be added to/removed from the pan before the balance marker will move 1 division
34
PEC (Primary Engineering Controls) devices include (3)\*
1. Laminar horizontal airflow work-benches (LAFWs) 2. Biological Safety Cabinets (BSCs) 3. Compounding aseptic isolators (CAIs) *aka. "glove box"*
35
batch preparation is considered ___ risk ISO requirements?
medium ex. multiple-dose vials of vanco used for bath prep of several IV admixtures made in **ISO 5** _laminar airflow hood_ that's located in an **ISO 7** _clean room_ and an **ISO 8** _ante room_
36
What's the sensitiviity of an analytical balance
electronic, single pan sensitivity of **0.1 mg** more accurate than bulk/counter balance
37
Sorbitol can be used as a
plasticizer/thickening agent
38
Ascorbic acid is a?
PRESERVATIVE
39
**_Magnesium stearate_** is a ? what is it most commonly used for?
insoluble FILLER the most commonly used "lubricant" diluent to prevent sticking to machinery
40
What kind of compounding agent is: Lecithin
emulsifying agent
41
Cetylpyridinium Cl is a?
PRESERVATIVE
42
Thimerosal is a? it's used in?
Preservative used in _vaccines_
43
A Class A or III prescription balance: minimum weight
120 mg
44
Glass mortar and pestles are preferred for mixing
liquids creams lotions *and for chemical that leave an oily residue or stain*
45
Emulsifiers are (2)
**Surfactants** **"wetting agents"**
46
What are the semi-synthetic hydrocolloids?
ethylcellulose ## Footnote **methylcellulose\***
47
What kind of compounding agent is: Sodium Benzoate
PRESERVATIVE
48
Refrigerator Temperature\*\*
2 C - 8 C | (35.6 F to 46.4 F)
49
What can you do to a wedgewood mortar prior
fill in the crevices w/ Lactose
50
Controlled room temp
20 C to 25 C
51
low-risk CSP prepared in a laminar flow hood (ISO class 5 PEC, that *cannot* be located within an ISO Class 7 buffer area) what's the BUD: Room temp? Refrigerated?
**12 hours for both** low risk non hazardous preparations only
52
Documentaiton and Record keeping inlcudes (4)
Formulation Record Compounding Record SOPs SDS/Material Safety Data Sheets (MSDSs)
53
Which emulsifying agents are also _thickeners?_
Agar Carageenan Gelatin Sorbitol
54
What is a **Suspending Agent**
a substance that _thickens_ liquids and helps **insoluble solids become evenly dispersed** in a liquid so that the **particles don't settle too quickly**
55
_Benzyl alcohol_ is used as a ___ and \_\_\_
**solvent & antimicrobial (**preservative)
56
Standard Operating Procedures (SOPs) include?
1. equipment maintenance 2. equipment calibration 3. handling 4. disposal of supplies
57
Chorhexidine gluconate is a?
PRESERVATIVE
58
bulk balance/counter balance weight limit
5 kg ## Footnote the 5 sort of looks like ***bottom of #5***
59
What are teh synthetic hydrocolloids?
Carbomers (Carbopol) poloxamers (Pluronic)
60
What kind of compounding agent is: PEG 400
emulsifying agent
61
What kind of compounding agent is: Phenyl mercuric acetate
PRESERVATIVE
62
What kind of compounding agent is: Nitromersal
PRESERVATIVE
63
What are the natural hydrocolloids
acacia alginic acid gelatin tragacanth xanthan gum
64
What kind of compounding agent is: EtOH (ethanol)
PRESERVATIVE
65
porcelain is ___ than wedgewood best for blending \_\_\_\_
smoother powders
66
an electronic balance is also known as a
**analytical balance**
67
GMS
Glycerol Monostearate emulsifying agent
68
69
Collagenase Ointments are for ....
debridement of skin wounds.
70
Glycerin Propylene Glycol Polyethylene Glycol 80 (PEG80) are they o/w OR w/o *levigating agents*
**o/w**
71
BUD for medium risk stored at room temp

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