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PassNaplexNow - NAPLEX review prep > Compounding > Flashcards

Compounding Flashcards

1
Q

advantage of a satellite pharmacy?

A

advantage is that the pharmacist is able to interact with other healthcare professionals and patients.

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2
Q

levigating agents/wetting agents for creams and ointments MUST BE….

A

compatible/miscible with the base

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3
Q

Levigation

A

“wet grinding’

process of reducing particle size of a solid (powder) by mixing it with a small amount of non-soluble liquid (this is the levigating agent)

consistency of putty/paste

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4
Q

Excessive heat defined as

A

> 40 C

(104 F)

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5
Q

What kind of compounding agent is:

Benzalkonium Cl

A

PRESERVATIVE

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6
Q

CARBOWAX is a name for

A

PEG

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7
Q

What kind of compounding agent is:

Cresol

A

PRESERVATIVE

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8
Q

What kind of compounding agent is:

SPAN 20, 40, 60

(sorbitan monolurate)

A

emulsifying agent

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9
Q

bulk balance/counter balance sensitivity

A

100mg

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10
Q

polyethylene monooleate is also known as?

A

PEG 400

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11
Q

What kind of compounding agent is:

Sodium Oleate

A

emulsifying agent

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12
Q

What kind of compounding agent is:

Sorbitan Stearate

A

emulsifying agent

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13
Q

What kind of compounding agent is:

Glycerol Monostearate

A

emulsifying agent

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14
Q

What kind of compounding agent is:

Polyglyceryl Oleate

A

emulsifying agent

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15
Q

What kind of compounding agent is:

Benzoic acid

A

PRESERVATIVE

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16
Q

What kind of compounding agent is:

Glycerol Monostearate

A

EMULSIFYING AGENT

(GMS)

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17
Q

Hydrocolloids are what type of agent?

A

Suspending agent

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18
Q

What kind of compounding agent is:

Benzethonium Cl

A

PRESERVATIVE

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19
Q

Freezer temp

A

-25 C to -10 C

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20
Q

The levigating agent must be _____ with the ointment base**

A

miscible

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21
Q

Parabens are?

A

Preservatives

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22
Q

What kind of compounding agent is:

Sodium Lauryl Sulfate

A

emulsifying agent

most H20 soluble

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23
Q

Which types of products need a “shake before use” auxillary label?

A
  1. suspensions
  2. lotions
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24
Q

What kind of compounding agent is:

Benzoic Acid

A

PRESERVATIVE

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25
Q

Polyoxyethylene Sorbitan

A

TWEEN

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26
Q

Carbomers are

A

gelling agents!

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27
Q

What kind of compounding agent is:

TWEEN

A

emulsifying agent

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28
Q

USP Regulation enforceable by the FDA apply to

(6)

A
  1. Ingredient Standards
  2. Documentation and Record Keeping
  3. Packaging and Storage
  4. Facilities & Equipment
  5. Quality Assurance & Quality Control
  6. Personnel
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29
Q

polysorbate is

30
Q

what’s a satellite pharmacy?

A

a pharmacy that is located in a patient care area and where the medications for patients are prepared nearby

away from the main (central) pharmacy location in a hospital.

must be staffed by @ least 1 pharmacist

31
Q

A Class A or III prescription balance:

maximum capacity

32
Q

levigation is the mos commonly used method when

A

incorporating solids into an ointment or cream

33
Q

A Class A or III prescription balance:

Sensitivy requirement or readibility***

A

must be at least 6 mg

(<5% of 120 mg - 120 mg being the max weight)

this means: no less than 120 mg may be weighed on the balance to maintain an error of < 5%

also means as much as 6 mg could be added to/removed from the pan before the balance marker will move 1 division

34
Q

PEC (Primary Engineering Controls) devices include (3)*

A
  1. Laminar horizontal airflow work-benches (LAFWs)
  2. Biological Safety Cabinets (BSCs)
  3. Compounding aseptic isolators (CAIs) aka. “glove box”
35
Q

batch preparation is considered ___ risk

ISO requirements?

A

medium

ex. multiple-dose vials of vanco used for bath prep of several IV admixtures

made in ISO 5 laminar airflow hood that’s located in an ISO 7 clean room and an ISO 8 ante room

36
Q

What’s the sensitiviity of an analytical balance

A

electronic, single pan

sensitivity of 0.1 mg

more accurate than bulk/counter balance

37
Q

Sorbitol can be used as a

A

plasticizer/thickening agent

38
Q

Ascorbic acid is a?

A

PRESERVATIVE

39
Q

Magnesium stearate is a ?

what is it most commonly used for?

A

insoluble FILLER

the most commonly used “lubricant” diluent to prevent sticking to machinery

40
Q

What kind of compounding agent is:

Lecithin

A

emulsifying agent

41
Q

Cetylpyridinium Cl is a?

A

PRESERVATIVE

42
Q

Thimerosal is a?

it’s used in?

A

Preservative

used in vaccines

43
Q

A Class A or III prescription balance:

minimum weight

44
Q

Glass mortar and pestles are preferred for mixing

A

liquids

creams

lotions

and for chemical that leave an oily residue or stain

45
Q

Emulsifiers are (2)

A

Surfactants

“wetting agents”

46
Q

What are the semi-synthetic hydrocolloids?

A

ethylcellulose

methylcellulose*

47
Q

What kind of compounding agent is:

Sodium Benzoate

A

PRESERVATIVE

48
Q

Refrigerator Temperature**

A

2 C - 8 C

(35.6 F to 46.4 F)

49
Q

What can you do to a wedgewood mortar prior

A

fill in the crevices w/ Lactose

50
Q

Controlled room temp

A

20 C to 25 C

51
Q

low-risk CSP prepared in a laminar flow hood (ISO class 5 PEC, that cannot be located within an ISO Class 7 buffer area)

what’s the BUD:

Room temp?

Refrigerated?

A

12 hours for both

low risk non hazardous preparations only

52
Q

Documentaiton and Record keeping inlcudes

(4)

A

Formulation Record

Compounding Record

SOPs

SDS/Material Safety Data Sheets (MSDSs)

53
Q

Which emulsifying agents are also thickeners?

A

Agar

Carageenan

Gelatin

Sorbitol

54
Q

What is a Suspending Agent

A

a substance that thickens liquids and helps insoluble solids become evenly dispersed in a liquid so that the particles don’t settle too quickly

55
Q

Benzyl alcohol is used as a ___ and ___

A

solvent & antimicrobial (preservative)

56
Q

Standard Operating Procedures (SOPs) include?

A
  1. equipment maintenance
  2. equipment calibration
  3. handling
  4. disposal of supplies
57
Q

Chorhexidine gluconate is a?

A

PRESERVATIVE

58
Q

bulk balance/counter balance weight limit

A

5 kg

the 5 sort of looks like bottom of #5

59
Q

What are teh synthetic hydrocolloids?

A

Carbomers (Carbopol)

poloxamers (Pluronic)

60
Q

What kind of compounding agent is:

PEG 400

A

emulsifying agent

61
Q

What kind of compounding agent is:

Phenyl mercuric acetate

A

PRESERVATIVE

62
Q

What kind of compounding agent is:

Nitromersal

A

PRESERVATIVE

63
Q

What are the natural hydrocolloids

A

acacia

alginic acid

gelatin

tragacanth

xanthan gum

64
Q

What kind of compounding agent is:

EtOH (ethanol)

A

PRESERVATIVE

65
Q

porcelain is ___ than wedgewood

best for blending ____

A

smoother

powders

66
Q

an electronic balance is also known as a

A

analytical balance

67
Q

GMS

A

Glycerol Monostearate

emulsifying agent

69
Q

Collagenase Ointments are for ….

A

debridement of skin wounds.

70
Q

Glycerin

Propylene Glycol

Polyethylene Glycol 80 (PEG80)

are they o/w OR w/o levigating agents

71
Q

BUD for medium risk stored at room temp

PassNaplexNow - NAPLEX review prep (41 decks)

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