CNS Stimulant Flashcards
1
Q
Ritalin IR Ritalin LA Methylin Concerta OROS Metadate CD
- MOA
- SEs
- DDIs
- DOC
- Indication:
- Other stimulants
A
Methylphenidate
- Ritalin IR: BID-TID b/4 meal. Max 20mg TID. Rapid abs
- Ritalin LA: Can open n sprinkled on applesauce
- Methylin: chewable tabs n oral sol’n
- Concerta OROS: osmotic system
Come in: 18, 27, 36, 54 mg ER - Metadate CD: 30% IR n 70% ER
- MOA: Increase dopamine and NE. Stimulants
- SEs: delayed onset of sleep, HA, decreased appetite = wt loss, slow growth, may exacerbate bipolar or psychotic condition. Heart problems pt, see cardiologist before.
Tics (most common with patch)
DDIs:
- MOA inhibitors
- Foods high in tyramine content
- TCAs
- Antihypertensive agents
- Sympathomimetics
- Warfarin
- Diamox: inc amphetamine [ ]
DOC
- School age children: amphetamine/methylphenidate
- Atomoxetine: use if fx object to tx with controlled sub
- Alpha-2 adrenergic: helpful when used combined
Indication: ADHD
2
Q
Quillivant
- Age
- Dose
- Indication
A
Methylphenidate XR oral sol’n
- Age: > 6 y.o
- Dose: 20mg PO QAM. Shake bottle for 10s. Require pharmacist to reconstitution.
- Indication: ADHD
3
Q
Daytrana
- Form
- Frequency
- Common SEs
- Indication
A
Methylphenidate Patch
- Transdermal patch. Worn daily 9hrs. Patch replaced QAM
- Tics (most common with patch)
- Indication: ADHD
4
Q
Focalin
- Frequency: IR/ER
- Indication
A
Dexmethylphenidate
- IR: BID
- ER: QD in AM. May sprinked over applesauce
- Indication: ADHD
5
Q
Dexedrine
- Indication
A
Dextroamphetamine
-Indication: Narcolepsy
6
Q
Vyvanse
- CS
- MOA
- Indication
- Dose
A
Lisdexamfetamine SR/IR
- CS: II = Abuse. IV or intranasal is less abuse
- MOA: stimulant
- Indication: ADHD
- Dose: 30mg PO QAM. Max 70mg/d
7
Q
Adderall IR/XR
- Indication
- Frequency: IR/XR
A
Dextroamphentamine + Amphetamine
- Indication ADHD, Narcolepsy
- IR: QD-BID given 1st thing in AM
- XR: QD
8
Q
Provigil
- Indication
- Warnings
A
MODafinil
- Indication: narcolepsy and shift work sleep disorder
Warnings
- Psychiatric problems: anxiety, hallucinations, suicidal ideations
- Serious allergic rxn (SJS): similar to lamictal
9
Q
Nuvigil
- Indication
A
ARModafinil
- Indication: Narcolepsy
10
Q
Strattera
- MOA
- Indication
- Adv
- Dose
- Warning
A
Atomoxetine = not CS
- MOA: selective NE reuptake inhibitor
- Indication: ADHD
- Adv: good for pets with anxiety, insomnia, or substance abuse disorders
- Dose: max 100mg
- Warning: severe liver injury and failure, priapism
11
Q
Intuniv
Tenex
- MOA
- Indication
- Dose
- SEs
A
Guanfacine = not CS
- MOA: non-stimulant. Stimulate alpha-2a adrenoreceptors
- Indication: ADHD (Tenex: tx high BP)
- Dose: QD tx for children age 6-17 y.o
- SEs: somnolence, HA, fatigue, abdominal pain.
12
Q
Kapvay
- MOA
- Indication
- Dose
A
Clonidine ER Tab
- MOA: Alpha 2 agonist
- Indication: the 1st and only therapy approved for use with stimulant med for the tx of ADHD.
Can use a mono therapy - Dose: start 0.1mg QD => titrate to BID
13
Q
Adipex-P
- CS
- Indication
A
Phentermine
- CS IV
- Indication: weight loss
14
Q
TENuate
- CS
- Indication
A
DIEThylpropion
- CS IV
- Indication: weight loss
15
Q
Didrex
- CS
- Indication
A
Benzphetamine
- CS III
- Indication: weight loss
16
Q
BONtril
- CS
- Indication
A
PhendiMETrazine
- CS III
- Indication: weight loss
17
Q
Xenical
- MOA:
- CS
- Indication
- Dose
- Counseling points
- SEs
A
Orlistat
- MOA: gastric and pancreatic lipases inhibitors: inhibiting dietary fat absorption by 30%. Decrease TG and TC abs
- CS: none
- Indication: weight loss
- Dose: 60-120 mg TID w/ or up to 1H after meals.
Xenical (Rx): 120mg capsule
=> if a meal is missed or has no fat, skip the dose
SEs
- GI: flatus with discharge. Oily stool w/ spotting. Fecal urgency and inconinence
- Malabsorption of fat soluble carotenoid
- Malabsorption of fat sol it: ADEK
18
Q
Belviq
- MOA
- CS Cat:
- Indication
- Dose
- Caution
A
Lorcaserin
- MOA: Selective 5-HT2C receptor agonist
- CS IV
- Indication: weight loss
- Dose: 10mg BID
- Caution: monitor for suicidal thought. Advise men to seek medical help for erection > 4H
19
Q
Qsymia
- Indication
- CS Cat
A
Phentermine + topiramate ER capsule
- Indication: weight loss
- CS IV => Phentamine
20
Q
Suprenza
- Form
- CS Cat
- Indication
A
Phentermine
- Form: ODT
- CS Cat: CS IV
- Indication: weight loss
21
Q
Regimex
- Indication
- CS Category
A
Benzphetamine
- I: Weight loss
- CS III
22
Q
Alli
- Dose
A
Orlistat
- (OTC): 60mg cap
23
Q
Contrave
- Indication
A
Naltrexone and Bupropion
- Indication: Weight loss
24
Q
Saxenda
A
Liraglutide
25
Dextrostat
- Indication
Dextroamphetamine
-Indication: Narcolepsy
