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Wrap-Up Block > OTC drugs > Flashcards

OTC drugs Flashcards

1
Q

3 general types of drugs that are particularly problematic for OTC drugs

A

EtOH
anti-coag
CNS therapy

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2
Q

What are Oxymetazoline and Xylometazoline

A

topical long-acting decongestants similar to Sympathomimetics

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3
Q

drugs that interact with acetominophen and cause liver damage

A

CYP inducers (phenytoin, carbamazine, rifampin, phenobarbitol)
Azoles
Macrolides
Warfarin

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4
Q

ADE NSAIDs

A

Tinnitus + Gastritis/GI Bleeding + Renal Failure

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5
Q

DDI w/ NSAIDs

A 
Warfarin 
Antihypertensive Rx (ARB + ACE-I / ɑ + β blockers) * all from PG interactions
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6
Q

conditions in which NSAID use should be cautioned

A 
Renal Failure
Gout (inhib Uric Acid elimination) 
Asthma (↑AA ---> Leukotrienes) 
CHF 
Elderly
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7
Q

OTC used for motion sickness

A

1st Generation anti-histamine [Diphenhydramine]

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8
Q

3 major components of Coricidin

A

Chlorpheniramine (Anti-Histamine) + Pseudoephedrine (Decongestant) + Dextromethorphan (Antitissuve)

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9
Q

Rhinitis Medicamentosa and Turbinate Hyperplasia are assc w./

A

prolonged use of topical decongestants (ex: affin and neosynephrine)

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10
Q

high dose causes: ↑warm feeling, ↑HR, ↑Dry Mouth/Throat, ↓Concentration

even higher dose causes PCP like effects : out-of-body + disorientation —> Addiction

A

dextromethorphan

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11
Q

how have manufacturers tried to prevent dextromethorphan abuse

A

formulated with /Guaifenesin (↑GI ADE to ↓dose) or Chlorpheniramine (↑toxicity)

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12
Q

where in the CNS does dextromethorphan work

A

medulla oblangata

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13
Q

instead of dextromethorphan what are mothers supposed to use for cough suppressant. whats the biggest concern

A

honey (not pasteurized –> botulism)

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14
Q

OTCs that affect BP

A

PEE comes out the TIP =

Phenylephrine, Ephedrine, Epi + Theophylline, Ibuprofen, Pseudoephedrine

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15
Q

OTC w/ ADE kidney stones

A

antacids (Inc Ca)

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16
Q

may cause anticoagulant probs + infectious diarrhea

A

Bismuth Subsalicylate [Pepto]

*↑salicylate toxicity from absorption of salicylate

17
Q

ADE: paralytic ileus

A

loperamide

18
Q

worry about chelation of other Rx + neutralize pH —> DDI

A

Magnesium Hydroxide/Sulfate

19
Q

intox with 1st gen anti-histamines may cause

A

Hallucinations + Euphoria + anti-cholinergic effects

20
Q

may cause cirrhosis + infectious diarrhea

A

loperamide

21
Q

cause of death in huffing

A

Arrhythmia + Suffocation (Vomit Aspirate)

22
Q

specific effect/toxicity seen in huffing

A

peroral/perinasal dermatitis

23
Q

OTC DOC for analgesia in kids

A

acetaminophen

24
Q

at what age are OTCs safe for use in kids

A

> 6 yo

25
Q

OTCs that worsen glaucoma + ↓urinary retention in elderly

A

Decongestants [Pseudoephedrine]

26
Q

OTCs that may lead to falls/fracturesin elderly

A

1st Generation Antihistamines

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