Anti-Other Parasites

Question 1

Which antihelmintic agent is active against both trematodes and cestodes

Answer 1

Praziquantel

Question 2

Which of the drugs for trypanosomiasis is an arsenical agent that enters the CNS

Answer 2

Melarsoprol

Question 3

MICROTUBULE INHIBITOR

Answer 3

MEBENDAZOLE

Question 4

inc Ca++ ENTRY –> PARALYSIS

Answer 4

PRAZIQUANTEL

Question 5

INHIBITS ELECTRON TRANSPORT

Answer 5

ATOVAQUONE

Question 6

DOC: African trypanosomiasis (before CNS involvement)

Answer 6

Suramin

Question 7

DOC for For a hepatic abscess or other extraintestinal disease

Answer 7

metronidazole or tinidazole

Question 8

used off- label for scabies, lice, and enterobiasis (pinworms)

Answer 8

Ivermectin

Question 9

DOC giardiasis, trichomoniasis, and amebiasis.

Answer 9

metronidazole or tinidazole

Question 10

s available OTC and is primarily used for the treatment of enterobiasis, commonly called pinworms (Enterobius vermicularis).

Answer 10

pyrantel

Question 11

is at least as efficacious as mebendazole for the treatment of many helminth infections.

Answer 11

Albendazole

Question 12

FA2012: Metallic Taste + Disulfiram Reaction (DDI EtOH) + Discolored Urine

Answer 12

Metronidazole

Question 13

chemical pancreatitis + bone marrow suppression

Answer 13

Sodium Stibogluconate

Question 14

binds nicotinic receptors —> depolarizing neuromusclar blockade —> spastic paralysis of worm muscle

Answer 14

Pyrantel Pamoate

Question 15

alter fliaria —> ↑phagocytosis

Answer 15

Diethylcarbamazine

Question 16

Anaerobes: un-ionized form take up —> reduce to active form —> cidal effects

Answer 16

Metronidazole

Question 17

↑delivery w/fatty meal

Answer 17

Atovaquone