Osteoarthritis (Week 12)

Question 1

what is the most common joint disease?

Answer 1

OA

Question 2

what is one of the leading causes of disability in the US?

Answer 2

OA

Question 3

before age 50, more (males/females) have more OA

Answer 3

males

Question 4

after age 70, more (males/females) have OA

Answer 4

females

Question 5

what factors cause OA

Answer 5

genetic predisposition & joint injury history

Question 6

what joints will obese people typically experience OA in

Answer 6

hip

knee

Question 7

how strong is the genetic factor in OA

Answer 7

accounts for 39-70%

seems to require more than one gene

Question 8

what happens in OA

Answer 8

• erosion and loss of articular cartilage in involved joint
• thickening and hardening (sclerosis) of bone beneath articular cartilage
• formation of osteophytes

Question 9

what will you see on an x-ray that indicates loss of cartilage

Answer 9

narrowing of joint space

Question 10

progression of OA

Answer 10

1. collagen flakes off surface of articular cartilage
2. deeper layers of cartilage form vertical fissures (fibrillation)
3. bone beneath deteriorating cartilage becomes dense and hard (sclerotic)
4. cartilage covered osteophytes grow outward from joint

Question 11

fibrillation

Answer 11

vertical fissures in deeper layers of cartilage

Question 12

symptoms of OA

Answer 12

1st- pain in joint with load bearing
pain
stiffness
limited AROM
limited PROM eventually
muscle wasting

Question 13

pseudoparesis

Answer 13

pain inhibition of muscle activity; leads to muscle becoming less able to contract
-leads to muscle wasting

Question 14

what age to symptoms of OA typically appear

Answer 14

40s and 50s

Question 15

how can pain onset help differentiate between RA and OA

Answer 15

in OA- pain subsides with rest

in RA-pain does not subside with rest

Question 16

joints most commonly affected by OA

Answer 16

hands
wrists
knees
feet
lower cervical
lumbar spine
shoulders
hips

Question 17

tx of OA

Answer 17

NSAIDs
rest
ROM to prevent loss of AROM
increase strength and flexibility around joint
weight loss
use of cane if LE

Question 18

types of surgical interventions for OA

Answer 18

releases
TKR
THR
last resort