OSCC Flashcards
1
Q
Prevalence of OSCC worldwide
A
1-2%
2
Q
Patients affected
A
80% are over 40
2M:F
50%+ will die of disease
3
Q
Risk factors for OSCC
A
Tobacco smokers are 4 times more likely than non smokers
Alcohol drinks are twice as likely. Related to dose
UV or sunlight exposure
Betel quid
Malnutrition
Infections - Candida, syphillis, HPV
Immunosuppression
4
Q
Where are the commonest sites for OSCC?
A
Tongue
Floor of mouth
Lower gum including retromolar pad
The sump
5
Q
What % of OSCC metastasise?
A
30-50%
6
Q
What is the three year survival of early and late stage disease?
A
Early 80%
Late 50%
7
Q
What factors influence prognosis of OSCC?
A
Site Age (over 80) Co morbidity Stage especially LN metastasis Surgical clearance, if margins more than 2mm 33% chance, if margins less than or equal to 2 m 66% of recurrence Dysplasia
8
Q
Treatment for OSCC
A
Surgery
Radiotherapy
Chemotherapy
None of the above