ORUC ET AL (1997) RESULTS/CONCLUSIONS

Question 1

Can you summarise the main result of the study?

Answer 1

• No significant association was found between having bipolar disorder and the polymorphisms in the 5HTR2A and 5HTR2C genes.
• Similarly, there was no significant association between having a family history of mood disorders and the polymorphisms in these genes.

Question 2

Can you summarise the gender related results of the study?

Answer 2

• Females with bipolar disorder were more likely to have polymorphisms in these serotonin receptor genes, suggesting a potential genetic risk factor for bipolar disorder specifically in women.