Orthopaedics 🦴 Flashcards
What is osteosarcoma
Malignant bone tumour found at metaphysis of distal femur or proximal tibia
Sx osteosarcoma
Dull bone pain worse at night
Localised mass
Soft tissue mass and swelling
Mx of osteosarcoma
Surgical resection and chemotherapy
Ix for osteosarcoma
X ray
Shows sunburst appearance
What is the most common primary malignancy of bone in children and adolescents
Osteosarcoma
What is Paget’s disease of bone
Increased bone turnover
Initially starts with increased osteoclastic activity then followed by increased osteoblast activity
Leads to bone deformities
What bones does Paget’s disease affect mainly
Commonly affects skull, spine, pelvis and long bones of lower extremities
Sx of Paget’s disease
Usually asx
But sx can include :
Constant achy bone pain
Warmness of bone
Hearing loss
Heart failure
Ix for Paget’s disease and their findings
Blood tests show raised ALP and normal calcium and phosphate
X RAY show osteolysis in early disease
Mx of Paget’s disease
only if symptomatic :
Bisphosphonates e.g IV pamidronate
Risk factors for Paget’s disease
Male sex
Increasing age
Anglo-Saxon descent
Family history
What is osteomyelitis
Infection of the bone
What causes osteomyelitis
Most common is staph aureus
Sx of osteomyelitis
Constant bone pain
Recent trauma
Redness and swelling
Fever
Mx of osteomyelitis
Abx
Flucloaxicillin for adults for 6 weeks
Cefazolin for children
Diagnostic imaging for osteomyelitis
MRI
What are the two ways of osteomyelitis occurring
Haemotagenous spread and non haemotagneous spread
Risk factors for haematogenous osteomyelitis
Endocarditis
IV drug use
Hickman line
Immunosuppression
Risk factors for non-haematogenous osteomyelitis
Skin ulcers
Trauma
Surgery