Orientation Week Flashcards

1
Q

Peripheral Vascular Symptoms

A
  • Diseases that involve arteries, veins, lymphatic

- Can be assessed via pulses

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2
Q

Peripheral venous Insufficiency

A
  • The body can’t get blood from the extremities back to the heart (DVT).
  • Stasis ulceration, painless, occurs at ankle area or lower leg just above the medial malleolus
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3
Q

Peripheral arterial insufficiency

A
  • Intermittent claudication
  • Decreased or absent pulses
  • Pale color when elevated, red when lowered, cool temp.
  • No or mild edema, thin shiny , loss hair over foot/toes, nail thickening.
  • Ulceration on toes or areas of trauma on feet, painful ulcers, gangrene may develop, compression not used
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4
Q

Asymptomatic Arterial Narrowing

A
  • Asymptomatic
  • Not presenting with any clinical problems
  • May suffer from atherosclerotic plaques etc
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5
Q

Symptomatic Arterial narrowing

A
  • Predictable

- Relieved by rest

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6
Q

Intermittent Claudication

A
  • Pain in the leg muscles that occurs during exercise and is relieved by rest.
  • Especially calf but if issue more proximal also thigh.
  • Condition seen in peripheral arterial disease
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7
Q

Critical Limb Ischaemia

A
  • Increasingly severe symptoms
  • Onset of symptoms with less exertion
  • Pain at rest
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8
Q

Claudication Distance

A

Distance pt can walk before onset of symptoms

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9
Q

Acute Limb Ischaemia

A
  • Complete Arterial Occlusion

- Present with 6 Ps

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10
Q

What are the 6 P’s?

A
  1. pale
  2. pulseless
  3. painful
  4. paralysed
  5. paraesthetic
  6. perishing with cold
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11
Q

Clarifying Symptoms

A
  • Speed of onset
  • Duration and frequency of symptoms
  • Severity (1-10)
  • Character of pain.
  • How do they experience pain
  • Radiation (where does pain go to)
  • Has pain changed
  • Associated symptoms (vomiting, collapsing, shortness of breath)
  • Aggravating and relieving symptoms
  • Effect on QofL (impact on family life, employment etc)
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12
Q

Non-modifiable risk factors

A
  1. Age
  2. Ethnicity
  3. Sex
  4. Personal/Family History of CVD
  5. Low Birth Weight
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13
Q

Modifiable risk factors

A
  1. Hypertension
  2. Hyperlipidaemia
  3. Diabetes
  4. Obesity
  5. Smoking
  6. Sedentary lifestyle
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14
Q

Past Medical History

A
  • Medical conditions
  • Visits to the Dr
  • Investigations
  • Procedures
  • Operations
  • Any problems On-going/fully-resolved/managed by medication
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15
Q

Diabetes

A
  • Managing blood sugar is not everything, will only marginally lower CVD risk.
  • Also have to look at cholesterol etc.
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16
Q

What is the most common cause of secondary hypertension?

A

Renal Disease

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17
Q

What is Hypertension?

A
  • Abnormally high blood pressure
  • Asymptomatic
  • Affects heart, kidneys and other organs
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18
Q

Primary hypertension

A
  • No known cause

- Most common

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19
Q

Secondary hypertension

A

High blood pressure caused by the effects of another disease (e.g., kidney disease)

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20
Q

Hyperthyroidism

A
  • A disorder caused by a thyroid gland that is faster than normal and overly productive
  • Results in a rapid pulse, nervousness, and loss of weight
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21
Q

Hypercholesterolaemia

A

Too much cholesterol in blood can lead to atherosclerosis

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22
Q

What is a True allergy?

A

Any med that causes a rash, itching, swelling, or difficulty breathing, otherwise it is an adverse reaction

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23
Q

List 5 Chest Pain Causes?

A
  1. Cardiovascular
  2. Respiratory - cancer, embolus
  3. Upper GI - oesophageal disease
  4. Musculoskeletal - trauma (broken rib)
  5. Other - Herpes Zoster
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24
Q

Stable angina

A
  • Chest pain or pressure precipitated by activities such as exercise or emotional stress which increase myocardial oxygen demand
  • NOT an acute coronary syndrome
  • Predictable in onset
  • Reproducible
  • Relieved by rest/GTN
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25
Q

Examples of Acute Coronary Syndromes

A
  • Unstable Angina

- Acute MI (NSTEMI & STEMI)

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26
Q

Coronary Artery Spasm

A
  • Variant Angina

- Occurs during rest, often at night

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27
Q

Costochondritis

A

An inflammation of the cartilage that connects a rib to the sternum

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28
Q

Angina

A

Narrowing of coronary arteries so that when heart rate increases there is not enough blood flow to meet the O2 demands of heart muscle

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29
Q

GTN

A
  • Glyceryl Trinitrate Spray

- Used as vasodilator for treatment of angina

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30
Q

Acute Myocardial Infarct

A
  • Can differentiate from unstable angina through tests
  • Blood test will show troponin release
  • ECG have to look at ST elevation
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31
Q

Pericarditis

A
  • Inflammation of pericardium
  • Viral/MI/TB/uraemia/malignany etc
  • Sharp/retrosternal pain
  • Relieved by sitting forwards
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32
Q

Aortic Dissection

A
  • Sudden and severe
  • Tearing of the inside of the aorta causing deep pain
  • Radiates to left shoulder/back
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33
Q

Dyspnoea

A
  • Shortness of breath
  • Acute, chronic or acute-on-chronic
  • 2 types in cardiac failure: orthopnoea/PND
  • Venous return is higher when lying down so get leaky pulmonary vessels resulting in fluid build up in lung tissues.
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34
Q

Orthopnoea

A
  • Shortness of breath (dyspnea) from lying flat.

- Relieved by patient being propped up in bed or sitting in a chair.

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35
Q

Paroxysmal Nocturnal dyspnoea

A
  • Awakening from sleep with dyspnoea and needing to be upright to achieve comfort.
  • Feel like they’re suffocating.
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36
Q

Palpitations

A
  • Feeling a heart-racing, pounding, or fluttering sensation in the chest
  • Uncomfortable sensations in the chest related to cardiac arrhythmias, such as premature ventricular contractions (PVCs)
  • Ask the pt to tap it out
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37
Q

Arrhythmia

A
  • Abnormal heart rhythm

- NOT all pts experience palpitations!

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38
Q

Extrasystoles

A
  • Extra beats of the heart
  • Ventricular or atrial
  • Heart jumps or ‘flutters’
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39
Q

Atrial fibrillation

A
  • May be unnoticed
  • Heart jumping about or racing
  • Associated breathlessness
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40
Q

Supraventricular Tachycardia

A
  • Heart racing or fluttering

- Associated polyuria

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41
Q

Ventricular Tachycardia

A
  • Heart racing or fluttering
  • Associated breathlessness
  • May be present as syncope rather than palpitations
  • A very rapid heartbeat that begins within the ventricles
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42
Q

Dizziness and Syncope

A
  • Postural hypotension
  • Neurocardiogenic (vasovagal)
  • Micturition syncope
  • Cardiac arrhythmias
  • Mechanical obstruction to cardiac output
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43
Q

Oedema

A
  • Abnormal accumulation of fluid in interstitial spaces

- Uni/Bilateral

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44
Q

Pitting oedema

A

Oedema thats demonstrated by applying pressure to the skin causing a lasting indentation.

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45
Q

Fatigue

A
  • Lots of different causes

- Side effect of beta blockers

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46
Q

Axillary Nodes

A
  • Lymphatic drainage of breast and other structures superficial to the thoracic wall
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47
Q

Pec Major

A
  • Clavicle, costal cartilage and sternum to intertubercular groove of humerus
  • Shoulder flexion and adduction
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48
Q

Pec Minor

A
  • Ribs 3, 4, 5 to the coracoid process
  • Stabilises scapula
  • Landmark for axillary artery and brachial plexus
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49
Q

Latissimus Dorsi

A
  • Iliac Crest, lower thoracic and lumbar vertebral spines to humerus
  • Shoulder extension and adduction
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50
Q

Serratus anterior

A
  • Upper 8 ribs to medial border of scapula

- Scapular protraction and rotation in shoulder abduction

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51
Q

Breast

A
  • Mammary gland in females
  • Glandular tissue in fibro-fatty stroma
  • 16 or so ducts converging on nipple
  • Lie opposite to ribs 2-6
  • Tail extending into axilla
  • Blood supply from axillary and internal thoracic arteries
  • Lymph drainage to axillary and internal thoracic nodes
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52
Q

Tumour Spread

A
- Breast lymph drainage described in 3 levels of severity for tumour spread into the axillary nodes
Level 1: anterior or pectoral group
Level 2: central group
Level 3: Apical group 
- Can also spread to internal nodes
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53
Q

Functions of thoracic wall

A
  • Respiratory movements: ribs, costal cartilages and intercostal movements, diaphragm
  • Protects major organs
  • Connects neck to upper limbs and abdomen
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54
Q

Pump Handle Inspiration

A

Rib elevation to push the sternum up and forward to increase thoracic anteriorposterior diameter

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55
Q

Bucket Handle inspiration

A

When additional increase in lateral diameter by rib eversion is required during enforced inspiration

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56
Q

Intercostal Muscles

A
  • Between ribs
  • Raise the ribs in inspiration but some may act in forced expiration to help lower the ribs
  • Intercostal neurovascular bundle at the lower edge of the rib (important for chest drain insertion)
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57
Q

Thoracic Inlet

A
  • T1, 1st ribs and costal cartilages and manubrium

- Slopes antero-inferiorly

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58
Q

Apex of lung

A

Extends upwards to the level of T1 and neck of 1st rib

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59
Q

Structures that cross 1st rib

A
  • Brachial plexus

- Subclavian artery and vein

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60
Q

Structures that pass through the thoracic inlet?

A
Pass between the thorax and the upper limb
From anterior to posterior:
-Subclavian vein
(scalenus anterior)
-Subclavian artery
-Inferior trunk of the brachial plexus

Pass between the thorax and neck

  • Vessels that supply and drain the head and neck
  • Trachea
  • Oesophagus
  • Nerves (right and left vagus, recurrent laryngeal, right and left phrenic nerves)
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61
Q

Thoracic outlet syndrome

A
  • Compression of the neurovascular bundle as it exits the thoracic outlet
  • Clincians call inlet the outlet as vessels move out of it
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62
Q

Dysplastic first rib

A
  • Can cause chronic trauma to the subclavian artery resulting in dissection and aneurysm
  • Trauma can then cause embolisation to the forearm
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63
Q

Thoracic Outlet

A
  • Closed by diaphragm
  • T12
  • 12th and 11th ribs
  • Costal cartilages of ribs 10, 9, 8 ,7
  • Xiphoid cartilage
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64
Q

Structures passing through diaphragm

A
"I ATE 10 eggs at 12"
T8 caval opening:
-IVC
-Right phrenic nerve
T10 oesophageal opening:
-Oesophagus
-Vagal trunks
-Left gastric vessels
T12 aortic hiatus:
-Aorta
-Azygos vein
-Thoracic duct
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65
Q

Body Cavitities

A

Lined by serous membranes with miniscule layer of fluid, lubricated potential space, friction free
Parietal and visceral layer
Thorax:
- lungs and chest wall lined by pleura
- Heart surrounded by pericardium
Abdomen and pelvis lined by peritoneum
Allows movement, expansion, contraction of organs

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66
Q

Pleura

A
  • Subdivided into mediastinal, diaphragmatic, costal and apex
  • Extends all the way down to 10th rib
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67
Q

Costodiaphragmatic recess

A
  • The lower area of the pleural cavity into which the lung expands on inspiration
  • Potential space between lung and diaphragm
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68
Q

What happens when Pleura ‘Turns the corner’?

A

Pleura turns the corner and reflects in relation to the rib landmarks 2, 4, 6, 8, 10, 12

69
Q

4 corners of the heart

A

3rd Right Costal cartilage
2nd Left Costal Cartilage
6th Right Costal Cartilage
5th Left Interspace (apex)

70
Q

Mediastinum

A
  • Central compartment of the thoracic cavity.
  • Structures in the midline of the thorax, between the left and right pleural cavitities.
  • It contains the heart, the great vessels of the heart, esophagus, trachea, phrenic nerve, cardiac nerve, thoracic duct, thymus, and lymph nodes of the central chest.
71
Q

Superior Mediastinum

A
  • Lies between the inlet and the plane between the sternal angle and T4/5, behind manubrium
  • Bifurcation of the pulmonary trunk is just inferior to the superior mediastinum
72
Q

Inferior Mediastinum

A
  • Lies inferior to the plane between the sternal angle and T4/5 and the thoracic outlet
  • Has 2 subdivisions within:
    1. Middle Mediastinum - contents of pericardium
    2. Posterior Mediastinum - aorta, oesophagus, thoracic duct, azygos veins
  • Sometimes the thymus in anterior mediastinum is counted as 3rd division
73
Q

Anterior Mediastinum

A

Lies behind the manubrium and sternum, anterior to the superior mediastinum and the upper part of the inferior mediastinum
Contains the thymus, which is active in children and atrophies with age leaving fatty remnant

74
Q

Middle Mediastinum

A

The pericardium and its contents

75
Q

Posterior Mediastinum

A

Structures behind the heart and pericardium

  • Azygos vein
  • Thoracic duct
  • Descending aorta
  • Oesophagus
76
Q

Pericardium

A
  • Fibrous and serous layers
  • Surround the heart so that it can move, expand and contract
  • Supports and stabilises
  • Double-layered serous membrane surrounding the heart
    Fibrous pericardium is fused with diaphragm
77
Q

Reflection

A

Turning point where visceral layer becomes parietal layer of pericardium

78
Q

Middle mediastinum

A

Consists of the pericardium and heart

79
Q

Fibrous Pericardium

A
  • Defines the middle mediastinum
  • Surrounds the heart and great vessels
  • Closed sac (fixed volume) attached superiorly to the roots of the great vessels (apex).
  • Attached inferiorly to the central tendon of the diaphragm (base of pericardium, not heart).
  • The phrenic nerves lie on either side of the sac and provides its sensory innervation (referred pain to shoulder tip)
80
Q

Cardiac Tamponade

A
  • Acute compression of the heart caused by fluid accumulation in the pericardial cavity
  • Can be due to pericarditis as inflammation can cause oedema or can bleed into sac causing excess fluid in the pericardial sac.
81
Q

Serous Pericardium

A
  • Parietal layer attached firmly to the internal surface of the fibrous layer.
  • Visceral layer attached firmly to the surface of the heart.
  • Both layers are continuous around the roots of the great vessels
  • Small film of lubricating fluid between the visceral and parietal layers.
82
Q

Pericardial sinuses (folds)

A
  • Subdivisions of the Pericardial Sac formed by reflections of the serous pericardium around the Great Vessels
  • Oblique and transverse
83
Q

Oblique sinus

A
  • Lies posterior to the heart
  • Potential space behind the left atrium
  • Venous end of cardiac tube has a number of branches which seperate and stretch out during development, dragging with it the pericardium.
84
Q

Transverse Sinus

A
  • Separates the great arteries and veins
  • Between arterial (anterior) and venous (posterior) ends
    Anterior - aorta and pulmonary trunk
    Posterior - SVC and left auricular appendage of left atrium
85
Q

Pulmonary circulation

A
  • Right heart pumps deoxygenated blood to the lungs

- Low pressure 12-16 mmHg

86
Q

Systemic Circulation

A
  • Left heart pumps oxygenated blood throughout the body systems
  • High pressure 70-120 mmHg
87
Q

Valve sequence

A
  1. Beginning of diastole. Aortic and pulmonary valves closed. Blood flows into
  2. Opening of atrio-ventricular (tricuspid and mitral) valves during early moments of diastole
  3. Atrial contraction during final moments of diastole
  4. Closure of atrioventricular valves (tricuspid and mitral) very soon after systole begins
  5. Opening of aortic and pulmonary valves during systole
88
Q

Route of blood

A
  1. Into right atrium
  2. Through tricuspid valve
  3. Into right ventricle
  4. Through Pulmonary valve
  5. Into pulmonary trunk to lung
  6. From lungs into left atrium
  7. Through mitral valve to left ventricle
  8. Through aortic valve to aorta and systemic circulation
89
Q

Chambers of the heart

A
  • Right side receives deoxygenated blood from IVC and SVC

- Left side receives oxygenated blood from the pulmonary veins

90
Q

Heart position

A

Lies against posterior structures, passes obliquely to anterior

91
Q

Heart Surfaces and Borders

A
  1. Anterior - sternocostal
  2. Inferior - Diaphragmatic
  3. Base - posterior surface
  4. Right border
  5. Left border
  6. Apex
92
Q

What makes up the Sternocostal surface?

A
  • Anterior
  • Right ventricle
  • Also slightly right atrium and auricle and left ventricle and auricle
93
Q

What makes up the Diaphragmatic surface?

A
  • Inferior

- Left and Right Ventricle

94
Q

What makes up the Base?

A
  • Posterior

- Left Atrium

95
Q

What makes up the Right Border?

A

Right atrium

96
Q

What makes up the Left Border?

A

Left ventricle and left auricle

97
Q

What makes up the Apex?

A
  • Formed by the left ventricle

- Palpable in the 5th left intercostal space, mid-clavicular line

98
Q

Surface markings

A

4 corners of the heart
Lies slightly obliquely with apex to the left
- 3rd Right CC
- 2nd Left CC
- 6th Right CC
- 5th Intercostal space, mid-clavicular line

99
Q

Cardiac and pericardial relations

A
  • Pleura, lungs and phrenic nerves on either side

- Oesphagus and descending thoracic aorta behind the base of the heart

100
Q

Right of the mediastinum

A
  • Related to the RA and veins
  • Arch of the azygos vein joins the SVC
  • Right phrenic follows path of SVC
  • SVC, Arch of Azygos, RA, IVC
101
Q

Left of the Mediastinum

A
  • Related to the LV and arteries
  • Left common carotid artery
  • Left Subclavian artery
  • Arch of aorta
  • Thoracic aorta
  • LV
  • Left phrenic
102
Q

Phrenic Nerves

A
  • Arise from cervical nerves C3, 4, 5 (keeps the diaphragm alive)
  • Enter the superior mediastinum between the venous and the arterial planes (posterior to the Brachiocephalic veins)
  • Pass between the fibrous pericardium and the parietal pleura
  • Both pass anterior to the hilum of each lung
103
Q

Right phrenic nerve

A
  • Related to veins
  • Passes to the right side of the SVC
  • Right atrium is anterior to the lung root
  • Right side of IVC to underside of diaphragm (T8)
  • Runs on the lateral side of the great veins (brachiocephalic, superior/inferior vena cava)
104
Q

Left Phrenic Nerve

A
  • Related to arteries, between Left common carotid and Left subclavian.
  • Arch of aorta is anterior (and lateral) to vagus
  • Anterior to the left lung root on pericardium over left ventricle
  • Pierces left dome of diaphragm near the apex of the heart
105
Q

Referred pain

A
  • Right and left phrenic nerves refer pain to the shoulder tip
  • Sole motor supply to the diaphragm
  • Sensory from the central tendon of the diaphragm and its parietal pleura and underlying peritoneum.
  • Sensory from the mediastinal parietal pleura
  • Sensory from the pericardium
106
Q

Lateral supraclavicular

A
  • C3, 4
  • Nerve supplies skin over shoulder, which is the C4 dermatome
  • Therefore structures with a sensory supply via the phrenic may refer pain to the should tip
107
Q

Pericardial Nerve Supply

A
  • Phrenic nerves are branches of the cervical plexus
  • Sensory supply to the fibrous and parietal pericardium, adjacent parietal pleura and motor supply to the whole diaphragm
  • Pain from pericardium may be referred to skin over the shoulder tip
108
Q

Myocardium

A
  • Thick middle muscle layer of the heart

- Syncitium is an organ where muscles work as a single unit

109
Q

Myogenic contraction

A

A contraction of the heart without external stimulation from a nerve.

110
Q

Endocardium

A
  • Endothelium
  • Lines chambers and valves
  • Inner lining of the heart
111
Q

Pericardium

A
  • Simple squamous epithelium secretes serous fluid

- A double-layered serous membrane that surrounds the heart

112
Q

Blood route

A
  • Right atrium receives deoxygenated blood from the body, sends it to the right ventricles and then to the lungs for oxygenation (pulmonary)
  • Left atrium receives oxygenated blood from the lungs, sends it to the left ventricle and then to the body (systematic)
113
Q

Right Atrium

A
  • Receives deoxygenated blood from SVC, IVC, coronary sinus
  • Blood leaves via the Tricuspid valve to the RV.
  • Anterior wall is trabeculated.
  • Posterior wall smooth
114
Q

Coronary Sinus

A

Drains blood from heart muscle itself

115
Q

Where is the Right Atrium Trabeculated?

A

Anterior wall trabeculated by musculi pectinati and crista terminalis

116
Q

Where/ What is the Interatrial septum?

A
  • Located on smooth posterior wall.

- Fossa ovalis and limbus fossa ovalis located here

117
Q

Nodes

A
  • Sinu-atrial node close to the opening of the SVC

- Atrioventricular node on septum between opening of coronary sinus and tricuspid valve

118
Q

Crista Terminalis

A
  • Vertical ridge that separates the smooth and rough right atrium.
  • Musculi pectinali and auricle arise from it
119
Q

Musculi Pectinati

A
  • Muscular ridges that modify the interior of both auricles and a portion of the right atrial wall.
  • Pass from the crista terminalis to the auricle.
  • Provide some power of contraction without majorly thickening the cardiac wall
120
Q

Fossa Ovalis

A
  • Site of what was the foramen ovale in the embryo

- Ridge surrounding the is the limbus fossa ovalis

121
Q

Foramen ovale

A

Opening from the right to left atrium that allowed oxygenated blood coming from the mother to by-pass the non-functioning foetal lungs

122
Q

Tricuspid valve

A
  • Tricuspid faces anteriorly and medially.
  • Opens to the right ventricle.
  • Inflow tract is forwards and medially through tricuspid valve.
  • Opens and closes due to blood pressure differences.
123
Q

Right Ventricle

A
  • Deoxygenated blood enters through tricuspid valve from right atrium.
  • Passes out through the infundibulum and pulmonary trunk.
  • Forms most of the sternocostal surface and some of the inferior surface
  • Walls are trabeculated
124
Q

Infundibulum

A
  • Entrance from right ventricle to pulmonary trunk. Wall is smooth.
  • Outflow tract upwards and backwards via smooth (laminar flow) infundibulum to pulmonary valve and trunk.
125
Q

Right Ventricle trabeculated

A
  • Trabeculae carneae
  • 3 papillary muscles with chordae tendineae
  • Septomarginal trabecula
126
Q

Trabeculae Carneae

A
  • Muscular ridges on the internal surface of the ventricles.
  • Give power of contraction without taking up space.
  • Give rise to papillary muscles
127
Q

Chordae tendineae

A

Strands of fibrous connective tissue that extend from the papillary muscle to the flaps of the right and left AV valves just before the ventricles contract, the papillary muscles contract and these to pull against the flaps of the valves allowing them to close but preventing inversion

128
Q

Papillary muscle

A
  • Cone-like projections on the ventricular walls, to which the chordae tendineae are attached.
  • 3 papillary muscles for 3 cusps in tricuspid valve. Only two in left ventricle.
  • Each papillary sends chordae tendoneae to 2 cusps
129
Q

Laminar flow

A
  • Smooth steady flow

- Promoted by smooth muscle (Infundibulum) at exit/outflow of ventricle

130
Q

Active Competence

A
  • Papillary muscles and chordae tendineae prevent cusp eversion during systole.
  • Tricuspid valve
131
Q

3 Cusps of tricuspid

A
  • Anterior, posterior, septal
  • Attached to the fibrous ring which is part of the fibrous skeleton of the heart
  • Closes during ventricular contraction (systole) prevents back flow to the atrium
132
Q

3 “watch-pocket” of Pulmonary Valve

A
  • Right, left, anterior
  • Opens during systole, Closes in diastole
  • Due to blood pressure differences
  • Passive competence
  • Attached to fibrous ring which is part of the skeleton of the heart
133
Q

Passive competence

A

No muscle contracting, its purely elastic recoil and blood pressure enabling the valves

134
Q

Pulmonary Trunk

A
  • Lies inferior to arch of aorta
  • Linked to aorta via ligamentum arteriosum
  • Divides to become left and right pulmonary arteries
135
Q

Left Atrium

A
  • Forms the base of the heart
  • Oxygenated blood from the lungs enters via the upper and lower, right and left pulmonary veins (4)
  • Outflow via bicuspid (mitral) valve
  • Interarterial wall smooth, can have slight depression = fossa ovalis
  • Long, tubular auricle visible on left cardiac border
  • Posterior to left atrium are the oesophagus and descending thoracic aorta
136
Q

Left Ventricle

A
  • Thick walled, systemic pressure (70-120 mmHg)
  • Left border
  • Apex beat
  • Inflow tract anteriorly through mitral valve towards the apex
  • Outflow tract upwards and backwards, posterior to the pulmonary valve and trunk
  • Circular in cross section because the interventricular wall bulges towards the right.
137
Q

Where does the Aortic valve lie in relation to pulmonary valve?

A

Lies posterior to pulmonary valve

138
Q

Aortic vestibule

A

Smooth upper walled part of the left ventricle; inferior to aortic valve

139
Q

Mitral/Bicuspid Valve

A
  • Closes during ventricular contraction (systole)
  • Prevents backflow to left atrium
  • 2 cusps (anterior, posterior) attached to the fibrous ring which is part of the skeleton of the heart
  • Active competance
140
Q

Aortic Valve

A
  • 3 Semi-lunar cusps at the apex of the aortic vestibule (right, left and posterior)
  • Attached to the fibrous ring which is part of the skeleton of the heart
  • Closes during ventricular relaxation (diastole), prevents backflow from aorta to left ventricle
  • Passive competance as no papillary muscles of chordae tendineae
141
Q

Coronary Arteries

A
  • During diastole the aortic valve is close allowing blood to arteries.
  • When valve is open in systole, blocks coronary arteries so no blood exits.
142
Q

Cardiac (fibrous) skeleton

A
  • Supports valves and myocardium.
  • Electrically separates atria and ventricles
  • Atrioventricular bundle of his should be the only conduction and connection between them.
  • Provides complete separation between atria and ventricles.
143
Q

Systole

A
  • Atria relax and fill with blood
  • Ventricle contract forcing blood upwards and backwards
  • Simultaneously the mitral and tricuspid valves close.
  • This is the 1st heart sound at the start of systole.
  • Forces blood through the aortic and pulmonary valves
144
Q

Diastole

A
  • Atrium contracts forcing blood through the mitral and tricuspid valves
  • Ventricles relax and fill with blood
  • Aortic and pulmonary valves closed by pressure of blood trying to come back under elastic recoil - 2nd heart sound at end of systole.
  • Aortic sinuses fill and blood enters coronary arteries
145
Q

Auscultation of valves

A
  1. Tricuspid, flow anteriorly and medially, ie towards the left. Listen at 4th/5th intercostal space just left of sternum
  2. Mitral, flow anteriorly and inferiorly towards the apex - listen at apex
  3. Aortic, flow superiorly and to the right - listen at right 2nd intercostal space
  4. Pulmonary, flow superiorly and towards the left - listen at left, 2nd intercostal space
146
Q

Valves

A
  • Lie in a line behind the sternum

- Cant hear through the sternum though so clinically listen at auscultation points

147
Q

Functions of CVS

A
  • Delivery system
  • Enables the bulk flow of materials
  • Temperature regulation
  • Homeostasis
  • Host defence (immune system)
  • Reproduction - blood inherent in male response
148
Q

Pressure

A
  • If central pressure of CVS drops, cant provide tissue with adequate blood flow.
  • It is a self-contained system of fluid so have to keep blood level topped up to maintain pressure to ensure demand is met
149
Q

Regulation and integration

A
  • CNS integrate overall activity of CVS with the activity and functions of the respiratory and renal systems
  • CNS controls autonomic nerves and hormones etc
  • Sympathetic nervous system effects blood vessels and blood pressure/volume
  • Both CNS and PNS can affect heart
  • Kidneys are a primary way that we can regulate blood volume
150
Q

Cardiovascular system

A
  • Right hand side pumps blood through the pulmonary circulation
  • Left hand side pumps blood though systemic circulation
  • Same volume of blood is pumped around each system in the same amount of time
151
Q

Describe the Heart Muscle?

A
  • The wall of the left ventricle is more muscular than the right as is pumping blood all around a higher pressure system.
  • Right hand side is pumping around a much smaller pulmonary system so less resistance from vessels
152
Q

What is Microcirculation?

A

The flow of blood through the arerioles, capillaries, and venules that is the site of exchange of gases, nutrients, and waste products with the cells.

153
Q

Parallel arrangement

A
  • Allows the independent regulation of blood flow to different organs
  • Adapts to the metabolic demands of the tissue
  • Balancing act, make sure can redirect to an area that needs it more ie muscles when excercising, whilst ensuring that all the other areas still have an adequate supply.
154
Q

High capacity system

A

Majority of the blood in systemic is held in the veins

155
Q

High pressure system

A

The arterial system is regulatory and a resistance generator. The real function of systemic circulation occurs here - the delivery of nutrients

156
Q

Normal path of blood flow

A
  • Pulmonary and systemic circulation are individual but need to be linked
  • Blood vessels vary in composition but all are lined by endothelial cells
157
Q

Rate of blood

A

At rest there are 5 litres per minute flowing around each system

158
Q

Blood vessels

A
  • All have ability to expand to expand to accommodate increase in volume.
  • All but the capillaries and venules have smooth muscle which gives them the ability to contract
159
Q

Describe Arterioles?

A

Smallest diameter muscular walled arteries

160
Q

Describe Precapillary sphincters?

A

Rings of smooth muscle which control entry of blood from arteriole into each capillary

161
Q

Describe Capillaries?

A
  • Smallest diameter blood vessel: simple tube, one cell thick, of flattened endothelial cells
  • Allows for diffusion of nutrients, waste etc in/out tissues
162
Q

Describe Venules?

A

Smallest diameter vessels which drain blood back to the larger true veins

163
Q

What does the heart pump have to overcome?

A

Generate enough pressure in ventricle to overcome the pressure in the aorta for blood to exit into systemic circulation

164
Q

What do Valves do?

A
  • Open passively - no open/close mechanism
  • All to do with pressures that flow across them
  • Prevent backflow of blood
165
Q

Describe Atrioventricular (cuspid) valves?

A
  • Tricuspid valve between right atrium and right ventricle
  • Bicuspid (mitral) valve between left atrium and left ventricle
  • Fairly flimsy
  • Attached to chordae tendineae
166
Q

Describe Semilunar valves?

A
  • Aortic valve between left ventricle and aorta
  • Pulmonary valve between right ventricle and pulmonary trunk
  • Both tricuspid
  • More heavy duty as have to deal with more stress and heavy abrasion
  • Smaller opening, higher pressure therefore more stress and abrasion
  • Greater pressure means dont need chordae tendoneae to keep them closed
167
Q

What is a Echocardiology?

A
  • Procedure studying heart motion

- Use ultrasound technology, or high-frequency sound waves, to create a visual image of a patient’s heart

168
Q

Describe Cardiac muscle?

A
  • Branched cells
  • Connected by desmosomes at the junction between cells (intercalated discs) which are strong cell-to-cell adhesion molecules
  • Striated (actin and mysoin filaments)
  • Smaller fibres with individual nucles (uninucleate)
  • Electrical connection through gap junctions - allow passage of ions, so action potential can spread
169
Q

Describe Intercalated discs?

A
  • Attachment sites between the transverse lines between cardiac muscle cells by desmosomes.
  • These allow impulses to move from one cell to another and securely fasten the cells together
  • Also contain gap junction that connect the cytoplasm to allow easy transfer of ions between cells